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Show Me the Science [Critique of Intelligent Design, by Daniel Dennett
New York Times ^ | August 28, 2005 | Daniel C. Dennett

Posted on 08/28/2005 2:14:36 PM PDT by AZLiberty

...

Is "intelligent design" a legitimate school of scientific thought? Is there something to it, or have these people been taken in by one of the most ingenious hoaxes in the history of science? Wouldn't such a hoax be impossible? No. Here's how it has been done.

...

(Excerpt) Read more at nytimes.com ...


TOPICS: Culture/Society; Philosophy; Technical
KEYWORDS: allcrevoallthetime; crevolist; crevorepublic; enoughalready; evolution; id; intelligentdesign; science; secularworry; walltowallcrevo; youmadeyourpointojay
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To: killermosquito
"If a person loses an eye why don't they grow a new one? Some lizzards can grow new tails so it would seem that the most evolved species should be able to grow new body parts if the need arises.

Why?

"Why do people need glasses? Why hasn't TOE eliminated the need for glasses?"

Because the ToE is a theory that explains how evolution works.

Your understanding of evolution has major holes in it. It also puts the cart before the horse. Evolution does not anticipate need, nor aim for absolute improvement.
Any 'improvements' come after a change in environment as a response to the change and are only improvements in the sense that the organism is enabled by the changes to have more offspring than those organisms without the change.

221 posted on 08/28/2005 8:10:52 PM PDT by b_sharp (Science adjusts theories to fit evidence, creationism distorts evidence to fit the Bible.)
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To: ml1954

True, TOE does not say that but life had to start somewhere and it wasn't by chance.


222 posted on 08/28/2005 8:11:05 PM PDT by killermosquito (Buffalo is what you get when liberalism runs its course.)
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To: plain talk

"Speciation is at the boundary between microevolution and macroevolution. Microevolution is a change over the genetics in a population's allele frequencies, mainly by genetic drift and natural selection. ...Yet the cumulative change during millions of speciation episodes over vast tracts of time must account for macroevolution, the level of change that is evident over the time scale of the fossil record."

This is not stating a "theory" of "microevolution". It is differentiating between evolutionary mechanisms that result in new species and those that don't. That is simply classification within a single theory, not a new theory.

I repeat, Darwin did not theorize a theory of "micro" evolution and a theory of "macro" evolution.

223 posted on 08/28/2005 8:12:30 PM PDT by ml1954
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To: killermosquito
True, TOE does not say that but life had to start somewhere and it wasn't by chance.

How do you know it wasn't by chance?

224 posted on 08/28/2005 8:12:52 PM PDT by WildTurkey (When will CBS Retract and Apologize?)
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To: killermosquito

but life had to start somewhere and it wasn't by chance.

How do you know?

225 posted on 08/28/2005 8:13:40 PM PDT by ml1954
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To: DCMB; 2ndreconmarine
Sheesh, how come everyone gets so touchy? I don't even go to church regularly :-). I just watched Privileged Planet and have read some really good articles that got me thinking. 'Scuse me if I offended anyone...

People are intense because this is a serious subject. The CS/ID folks are using a lie (i.e., that ID is not religiously based) to wedge (and mandate) the study of the bible into public schools (e.g., Kansas).

Folks who have devoted their lives to science are watching the equivalent of witchcraft, flat earth theory, and astrology being forced into schools.

This is why people are touchy.

I would say its the same on the other side, but it is the CS/ID folks who started this war with their efforts to teach ID in schools.

226 posted on 08/28/2005 8:14:45 PM PDT by Coyoteman (Is this a good tagline?)
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To: WildTurkey

According to you "thinking persons" believe that life and the complexity within it occured by random chance.

I have all the evidence I need and wear my creationist badge with pride.


227 posted on 08/28/2005 8:17:33 PM PDT by killermosquito (Buffalo is what you get when liberalism runs its course.)
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To: WildTurkey

How do you know it was?


228 posted on 08/28/2005 8:19:11 PM PDT by killermosquito (Buffalo is what you get when liberalism runs its course.)
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To: killermosquito

You might appreciate this. Please note the part about the mutated mosquitos.




The Mosquito Killerdownload pdf

homeblinkthe tipping pointthe new yorker archiveetc.

July 2, 2001
ANNALS OF PUBLIC HEALTH

Millions of people owe their lives to Fred Soper.
Why isn't he a hero?


1.

In the late nineteen-thirties, a chemist who worked for the J.R. Geigy company, in Switzerland, began experimenting with an odorless white crystalline powder called dichloro-diphenyl-trichloroethane. The chemist, Paul Müller, wanted to find a way to protect woollens against moths, and his research technique was to coat the inside of a glass box with whatever chemical he was testing, and then fill it with houseflies. To his dismay, the flies seemed unaffected by the new powder. But, in one of those chance decisions on which scientific discovery so often turns, he continued his experiment overnight--and in the morning all the flies were dead. He emptied the box, and put in a fresh batch of flies. By the next morning, they, too, were dead. He added more flies, and then a handful of other insects. They all died. He scrubbed the box with an acetone solvent, and repeated the experiment with a number of closely related compounds that he had been working with. The flies kept dying. Now he was excited: had he come up with a whole line of potent new insecticides? As it turned out, he hadn't. The new candidate chemicals were actually useless. To his amazement, what was killing the flies in the box were scant traces of the first compound, dichloro-diphenyl-trichloroethane--or, as it would come to be known, DDT.

In 1942, Geigy sent a hundred kilograms of the miracle powder to its New York office. The package lay around, undisturbed, until another chemist, Victor Froelicher, happened to translate the extraordinary claims for DDT into English, and then passed on a sample to the Department of Agriculture, which in turn passed it on to its entomology research station, in Orlando, Florida. The Orlando laboratory had been charged by the Army to develop new pesticides, because the military, by this point in the war, was desperate for a better way to protect its troops against insect-borne disease. Typhus--the lethal fever spread by lice--had killed millions of people during and after the First World War and was lurking throughout the war zones. Worse, in almost every theatre of operations, malaria-carrying mosquitoes were causing havoc. As Robert Rice recounted in this magazine almost fifty years ago, the First Marine Division had to be pulled from combat in 1942 and sent to Melbourne to recuperate because, out of seventeen thousand men, ten thousand were incapacitated with malarial headaches, fevers, and chills. Malaria hit eighty-five per cent of the men holding onto Bataan. In fact, at any one time in the early stages of the war, according to General Douglas MacArthur, two-thirds of his troops in the South Pacific were sick with malaria. Unless something was done, MacArthur complained to the malariologist Paul Russell, it was going to be "a long war." Thousands of candidate insecticides were tested at Orlando, and DDT was by far the best.

To gauge a chemical's potential against insects, the Orlando researchers filled a sleeve with lice and a candidate insecticide, slipped the sleeve over a subject's arm, and taped it down at both ends. After twenty-four hours, the dead lice were removed and fresh lice were added. A single application of DDT turned out to kill lice for a month, almost four times longer than the next-best insecticide. As Rice described it, researchers filled twelve beakers with mosquito larvae, and placed descending amounts of DDT in each receptacle--with the last beaker DDT free. The idea was to see how much chemical was needed to kill the mosquitoes. The mosquito larvae in every beaker died. Why? Because just the few specks of chemical that floated through the air and happened to land in the last beaker while the experiment was being set up were enough to kill the mosquitoes. Quickly, a field test was scheduled. Two duck ponds were chosen, several miles apart. One was treated with DDT. One was not. Spraying was done on a day when the wind could not carry the DDT from the treated to the untreated pond. The mosquito larvae in the first pond soon died. But a week later mosquito larvae in the untreated pond also died: when ducks from the first pond visited the second pond, there was enough DDT residue on their feathers to kill mosquitoes there as well.

The new compound was administered to rabbits and cats. Rice tells how human volunteers slathered themselves with it, and sat in vaults for hours, inhaling the fumes. Tests were done to see how best to apply it. "It was put in solution or suspension, depending on what we were trying to do," Geoffrey Jeffery, who worked on DDT at the Tennessee Valley Authority, recalls. "Sometimes we'd use some sort of petroleum-based carrier, even diesel oil, or add water to a paste or concentration and apply it on the wall with a Hudson sprayer." Under conditions of great secrecy, factories were set up, to manufacture the new chemical by the ton. It was rushed to every Allied theatre. In Naples, in 1944, the Army averted a catastrophic typhus epidemic by "dusting" more than a million people with DDT powder. The Army Air Force built DDT "bombs," attaching six-hundred-and-twenty-five-gallon tanks to the underside of the wings of B-25s and C-47s, and began spraying Pacific beachheads in advance of troop arrivals. In Saipan, invading marines were overtaken by dengue, a debilitating fever borne by the Aedes variety of mosquito. Five hundred men were falling sick every day, each incapacitated for four to five weeks. The medical officer called in a DDT air strike that saturated the surrounding twenty-five square miles with nearly nine thousand gallons of five-per-cent DDT solution. The dengue passed. The marines took Saipan.

It is hard to overestimate the impact that DDT's early success had on the world of public health. In the nineteen-forties, there was still malaria in the American South. There was malaria throughout Europe, Asia, and the Caribbean. In India alone, malaria killed eight hundred thousand people a year. When, in 1920, William Gorgas, the man who cleansed the Panama Canal Zone of malaria, fell mortally ill during a trip through England, he was knighted on his deathbed by King George V and given an official state funeral at St. Paul's Cathedral--and this for an American who just happened to be in town when he died. That is what it meant to be a malaria fighter in the first half of the last century. And now there was a chemical--the first successful synthetic pesticide--that seemed to have an almost magical ability to kill mosquitoes. In 1948, Müller won the Nobel Prize for his work with DDT, and over the next twenty years his discovery became the centerpiece of the most ambitious public-health campaign in history.

Today, of course, DDT is a symbol of all that is dangerous about man's attempts to interfere with nature. Rachel Carson, in her landmark 1962 book, "Silent Spring," wrote memorably of the chemical's environmental consequences, how its unusual persistence and toxicity had laid waste to wildlife and aquatic ecosystems. Only two countries--India and China--continue to manufacture the substance, and only a few dozen more still use it. In May, at the Stockholm Convention on Persistent Organic Pollutants, more than ninety countries signed a treaty, placing DDT on a restricted-use list, and asking all those still using the chemical to develop plans for phasing it out entirely. On the eve of its burial, however--and at a time when the threat of insect-borne disease around the world seems to be resurgent--it is worth remembering that people once felt very differently about DDT, and that between the end of the Second World War and the beginning of the nineteen-sixties it was considered not a dangerous pollutant but a lifesaver. The chief proponent of that view was a largely forgotten man named Fred Soper, who ranks as one of the unsung heroes of the twentieth century. With DDT as his weapon, Soper almost saved the world from one of its most lethal afflictions. Had he succeeded, we would not today be writing DDT's obituary. We would view it in the same heroic light as penicillin and the polio vaccine.

2.

Fred Soper was a physically imposing man. He wore a suit, it was said, like a uniform. His hair was swept straight back from his forehead. His eyes were narrow. He had large wire-rimmed glasses, and a fastidiously maintained David Niven mustache. Soper was born in Kansas in 1893, received a doctorate from the Johns Hopkins School of Public Health, and spent the better part of his career working for the Rockefeller Foundation, which in the years before the Second World War--before the establishment of the United Nations and the World Health Organization--functioned as the world's unofficial public-health directorate, using its enormous resources to fight everything from yellow fever in Colombia to hookworm in Thailand.

In those years, malaria warriors fell into one of two camps. The first held that the real enemy was the malaria parasite--the protozoan that mosquitoes pick up from the blood of an infected person and transmit to others. The best way to break the chain of infection, this group argued, was to treat the sick with antimalarial drugs, to kill the protozoan so there was nothing for mosquitoes to transmit. The second camp held, to the contrary, that the mosquito was the real enemy, since people would not get malaria in the first place if there were no mosquitoes around to bite them. Soper belonged to the latter group, and his special contribution was to raise the killing of mosquitoes to an art. Gorgas, Soper's legendary predecessor, said that in order to fight malaria you had to learn to think like a mosquito. Soper disagreed. Fighting malaria, he said, had very little to do with the intricacies of science and biology. The key was learning to think like the men he hired to go door-to-door and stream-to-stream, killing mosquitoes. His method was to apply motivation, discipline, organization, and zeal, in understanding human nature. Fred Soper was the General Patton of entomology.

While working in South America in 1930, Soper had enforced a rigorous protocol for inspecting houses for mosquito infestation, which involved checking cisterns and climbing along roof gutters. (He pushed himself so hard perfecting the system in the field that he lost twenty-seven pounds in three months.) He would map an area to be cleansed of mosquitoes, give each house a number, and then assign each number to a sector. A sector, in turn, would be assigned to an inspector, armed with the crude pesticides then available; the inspector's schedule for each day was planned to the minute, in advance, and his work double-checked by a supervisor. If a supervisor found a mosquito that the inspector had missed, he received a bonus. And if the supervisor found that the inspector had deviated by more than ten minutes from his preassigned schedule the inspector was docked a day's pay. Once, in the state of Rio de Janeiro, a large ammunition dump--the Niterói Arsenal--blew up. Soper, it was said, heard the explosion in his office, checked the location of the arsenal on one of his maps, verified by the master schedule that an inspector was at the dump at the time of the accident, and immediately sent condolences and a check to the widow. The next day, the inspector showed up for work, and Soper fired him on the spot--for being alive. Soper, in one memorable description, "seemed equally capable of browbeating man or mosquito." He did not engage in small talk. In 1973, at Soper's eightieth-birthday party, a former colleague recounted how much weight he had lost working for Soper; another told a story of how Soper looked at him uncomprehendingly when he asked to go home to visit his ailing wife; a third spoke of Soper's betting prowess. "He was very cold and very formal," remembers Andrew Spielman, a senior investigator in tropical disease at the Harvard School of Public Health and the author, with Michael D'Antonio, of the marvellous new book "Mosquito: A Natural History of Our Most Persistent and Deadly Foe." "He always wore a suit and tie. With that thin little mustache and big long upper lip, he scared the hell out of me."

One of Soper's greatest early victories came in Brazil, in the late nineteen-thirties, when he took on a particularly vicious strain of mosquito known as Anopheles gambiae. There are about twenty-five hundred species of mosquito in the world, each with its own habits and idiosyncrasies--some like running water, some like standing water, some bite around the ankles, some bite on the arms, some bite indoors, some bite outdoors--but only mosquitoes of the genus Anopheles are capable of carrying the human malaria parasite. And, of the sixty species of Anopheles that can transmit malaria, gambiae is the variety best adapted to spreading the disease. In California, there is a strain of Anopheles known as freeborni, which is capable of delivering a larger dose of malaria parasite than gambiae ever could. But freeborni is not a good malaria vector, because it prefers animals to people. Gambiae, by contrast, bites humans ninety-five per cent of the time. It has long legs and yellow-and-black spotted wings. It likes to breed in muddy pools of water, even in a water-filled footprint. And, unlike many mosquitoes, it is long-lived, meaning that once it has picked up the malaria parasite it can spread the protozoan to many others. Gambiae gathers in neighborhoods in the evenings, slips into houses at dusk, bites quietly and efficiently during the night, digests its "blood meal" while resting on the walls of the house, and then slips away in the morning. In epidemiology, there is a concept known as the "basic reproduction number," or BRN, which refers to the number of people one person can infect with a contagious disease. The number for H.I.V., which is relatively difficult to transmit, is just above one. For measles, the BRN is between twelve and fourteen. But with a vector like gambiae in the picture the BRN for malaria can be more than a hundred, meaning that just one malarious person can be solely responsible for making a hundred additional people sick. The short answer to the question of why malaria is such an overwhelming problem in Africa is that gambiae is an African mosquito.

In March, 1930, a Rockefeller Foundation entomologist named Raymond Shannon was walking across tidal flats to the Potengi River, in Natal, Brazil, when he noticed, to his astonishment, two thousand gambiae larvae in a pool of water, thousands of miles from their homeland. Less than a kilometre away was a port where French destroyers brought mail across the Atlantic from Africa, and Shannon guessed that the mosquito larvae had come over, fairly recently, aboard one of the mail ships. He notified Soper, who was his boss, and Soper told Brazilian officials to open the dykes damming the tidal flats, because salt water from the ocean would destroy the gambiae breeding spots. The government refused. Over the next few years, there were a number of small yet worrisome outbreaks of malaria, followed by a few years of drought, which kept the problem in check. Then, in 1938, the worst malaria epidemic in the history of the Americas broke out. Gambiae had spread a hundred and fifty miles along the coast and inland, infecting a hundred thousand people and killing as many as twenty thousand. Soper was called in. This was several years before the arrival of DDT, so he brought with him the only tools malariologists had in those years: diesel oil and an arsenic-based mixture called Paris green, both of which were spread on the pools of water where gambiae larvae bred; and pyrethrum, a natural pesticide made from a variety of chrysanthemum, which was used to fumigate buildings. Four thousand men were put at his disposal. He drew maps and divided up his troops. The men wore uniforms, and carried flags to mark where they were working, and they left detailed written records of their actions, to be reviewed later by supervisors. When Soper discovered twelve gambiae in a car leaving an infected area, he set up thirty de-insectization posts along the roads, spraying the interiors of cars and trucks; seven more posts on the rail lines; and defumigation posts at the ports and airports. In Soper's personal notes, now housed at the National Library of Medicine, in Bethesda, there is a cue card, on which is typed a quotation from a veteran of the Rockefeller Foundation's efforts, in the early twentieth century, to eradicate hookworm. "Experience proved that the best way to popularize a movement so foreign to the customs of the people . . . was to prosecute it as though it were the only thing in the universe left undone." It is not hard to imagine the card tacked above Soper's desk in Rio for inspiration: his goal was not merely to cripple the population of gambiae, since that would simply mean that they would return, to kill again. His goal was to eliminate gambiae from every inch of the region of Brazil that they had colonized--an area covering some eighteen thousand square miles. It was an impossible task. Soper did it in twenty-two months.

3.

While DDT was being tested in Orlando, Soper was in North Africa with the United States Typhus Commission, charged with preventing the kind of louse-spread typhus epidemics that were so devastating during the First World War. His tool of choice was a delousing powder called MYL. Lice live in the folds of clothing, and a previous technique had been to treat the clothing after people had disrobed. But that was clearly not feasible in Muslim cities like Cairo and Algiers, nor was it practical for large-scale use. So Soper devised a new technique. He had people tie their garments at the ankles and wrists, and then he put the powder inside a dust gun, of the sort used in gardening, and blew it down the collar, creating a balloon effect. "We were in Algiers, waiting for Patton to get through Sicily," Thomas Aitken, an entomologist who worked with Soper in those years, remembers. "We were dusting people out in the countryside. This particular day, a little old Arab man, only about so high, came along with his donkey and stopped to talk to us. We told him what we were doing, and we dusted him. The next day, he comes by again and says that that had been the first time in his life that he had ever been able to sleep through the night."

In December of 1943, the typhus team was dispatched to Naples, where in the wake of the departing German Army the beginnings of a typhus epidemic had been detected. The rituals of Cairo were repeated, only this time the typhus fighters, instead of relying on MYL (which easily lost its potency), were using DDT. Men with dusters careered through the narrow cobblestoned streets of the town, amid the wreckage of the war, delousing the apartment buildings of typhus victims. Neapolitans were dusted as they came out of the railway stations in the morning, and dusted in the streets, and dusted in the crowded grottoes that served as bomb shelters beneath the city streets. In the first month, more than 1.3 million people were dusted, saving countless lives.

Soper's diary records a growing fascination with this new weapon. July 25, 1943: "Lunch with L.L. Williams and Justin Andrews. L.L. reports that he has ordered 10,000 lbs of Neocid [DDT]and that Barber reports it to be far superior to [Paris Green]for mosquitoes." February 25, 1944: "Knipling visits laboratory. Malaria results [for DDT]ARE FANTASTIC." When Rome fell, in mid-1944, Soper declared that he wanted to test DDT in Sardinia, the most malarious part of Italy. In 1947, he got his wish. He pulled out his old organization charts from Brazil. The island--a rocky, mountainous region the size of New Hampshire, with few roads--was mapped and divided up hierarchically, the smallest unit being the area that could be covered by a sprayer in a week. Thirty-three thousand people were hired. More than two hundred and eighty-six tons of DDT were acquired. Three hundred and thirty-seven thousand buildings were sprayed. The target Anopheles was labranchiae, which flourishes not just in open water but also in the thick weeds that surround the streams and ponds and marshes of Sardinia. Vegetation was cut back, and a hundred thousand acres of swampland were drained. Labranchiae larvae were painstakingly collected and counted and shipped to a central laboratory, where precise records were kept of the status of the target vector. In 1946, before the campaign started, there were seventy-five thousand malaria cases on the island. In 1951, after the campaign finished, there were nine.

"The locals regarded this as the best thing that had ever happened to them," Thomas Aitken says. He had signed on with the Rockefeller Foundation after the war, and was one of the leaders of the Sardinian effort. "The fact that malaria was gone was welcome," he went on. "But also the DDT got rid of the houseflies. Sardinian houses were made of stone. The wires for the lights ran along the walls near the ceiling. And if you looked up at the wires they were black with housefly droppings from over the years. And suddenly the flies disappeared." Five years ago, Aitken says, he was invited back to Sardinia for a celebration to mark the forty-fifth anniversary of malaria's eradication from the island. "There was a big meeting at our hotel. The public was invited, as well as a whole bunch of island and city officials, the mayor of Cagliari, and representatives of the Italian government. We all sat on a dais, at the side of the room, and I gave a speech there, in Italian, and when I finished everybody got up and clapped their hands and was shouting. It was very embarrassing. I started crying. I couldn't help it. Just reminiscing now . . ."

Aitken is a handsome, courtly man of eighty-eight, lean and patrician in appearance. He lives outside New Haven, in an apartment filled with art and furniture from his time in Sardinia. As he thought back to those years, there were tears in his eyes, and at that moment it was possible to appreciate the excitement that gripped malariologists in the wake of the Second World War. The old-school mosquito men called themselves mud-hen malariologists, because they did their job in swamps and ditches and stagnant pools of water. Paris green and pyrethrum were crude insecticides that had to be applied repeatedly; pyrethrum killed only those mosquitoes that happened to be in the room when you were spraying. But here, seemingly, was a clean, pure, perfectly modern weapon. You could spray a tiny amount on a wall, and that single application would kill virtually every mosquito landing on that surface for the next six months. Who needed a standing army of inspectors anymore? Who needed to slog through swamps? This was an age of heroics in medicine. Sabin and Salk were working on polio vaccines with an eye to driving that disease to extinction. Penicillin was brand new, and so effective that epidemiologists were dreaming of an America without venereal disease. The extinction of smallpox, that oldest of scourges, seemed possible. All the things that we find sinister about DDT today--the fact that it killed everything it touched, and kept on killing everything it touched--were precisely what made it so inspiring at the time. "The public-health service didn't pay us a lot," says McWilson Warren, who spent the early part of his career fighting malaria in the Malaysian jungle. "So why were we there? Because there was something so wonderful about being involved with people who thought they were doing something more important than themselves." In the middle of the war, Soper had gone to Egypt, and warned the government that it had an incipient invasion of gambiae. The government ignored him, and the next year the country was hit with an epidemic that left more than a hundred thousand dead. In his diary, Soper wrote of his subsequent trip to Egypt, "In the afternoon to the Palace where Mr. Jacobs presents me to His Majesty King Faruk. The King says that he is sorry to know that measures I suggested last year were not taken at that time." Soper had triumphed over gambiae in Brazil, driven lice from Cairo and Naples, and had a weapon, DDT, that seemed like a gift from God--and now kings were apologizing to him. Soper started to dream big: Why not try to drive malaria from the entire world?

4.

Fred Soper's big idea came to be known as the Global Malaria Eradication Programme. In the early nineteen-fifties, Soper had been instrumental in getting the Brazilian malariologist Marcolino Candau--whom he had hired during the anti-gambiae campaign of the nineteen-thirties--elected as director-general of the World Health Organization, and, in 1955, with Candau's help, Soper pushed through a program calling on all member nations to begin a rigorous assault on any malaria within their borders. Congress was lobbied, and John Kennedy, then a senator, became an enthusiastic backer. Beginning in 1958, the United States government pledged the equivalent of billions in today's dollars for malaria eradication--one of the biggest commitments that a single country has ever made to international health. The appeal of the eradication strategy was its precision. The idea was not to kill every Anopheles mosquito in a given area, as Soper had done with gambiae in Brazil. That was unnecessary. The idea was to use DDT to kill only those mosquitoes which were directly connected to the spread of malaria--only those which had just picked up the malaria parasite from an infected person and were about to fly off and infect someone else. When DDTis used for this purpose, Spielman writes in "Mosquito," "it is applied close to where people sleep, on the inside walls of houses. After biting, the mosquitoes generally fly to the nearest vertical surface and remain standing there for about an hour, anus down, while they drain the water from their gut contents and excrete it in a copious, pink-tinged stream. If the surfaces the mosquitoes repair to are coated by a poison that is soluble in the wax that covers all insects' bodies, the mosquitoes will acquire a lethal dose." Soper pointed out that people who get malaria, and survive, generally clear their bodies of the parasite after three years. If you could use spraying to create a hiatus during which minimal transmission occurred--and during which anyone carrying the parasite had a chance to defeat it--you could potentially eradicate malaria. You could stop spraying and welcome the mosquitoes back, because there would be no more malaria around for them to transmit. Soper was under no illusions about how difficult this task would be. But, according to his calculations, it was technically possible, if he and his team achieved eighty-per-cent coverage--if they sprayed eight out of every ten houses in infected areas.

Beginning in the late fifties, DDT was shipped out by the ton. Training institutes were opened. In India alone, a hundred and fifty thousand people were hired. By 1960, sixty-six nations had signed up. "What we all had was a handheld pressure sprayer of three-gallon capacity," Jesse Hobbs, who helped run the eradication effort in Jamaica in the early sixties, recalls. "Generally, we used a formulation that was water wettable, meaning you had powder you mixed with water. Then you pressurized the tank. The squad chief would usually have notified the household some days before. The instructions were to take the pictures off the wall, pull everything away from the wall. Take the food and eating utensils out of the house. The spray man would spray with an up-and-down movement--at a certain speed, according to a pattern. You started at a certain point and sprayed the walls and ceiling, then went outside to spray the eaves of the roof. A spray man could cover ten to twelve houses a day. You were using about two hundred milligrams per square foot of DDT, which isn't very much, and it was formulated in a way that you could see where you sprayed. When it dried, it left a deposit, like chalk. It had a bit of a chlorine smell. It's not perfume. It's kind of like swimming-pool water. People were told to wait half an hour for the spray to dry, then they could go back." The results were dramatic. In Taiwan, much of the Caribbean, the Balkans, parts of northern Africa, the northern region of Australia, and a large swath of the South Pacific, malaria was eliminated. Sri Lanka saw its cases drop to about a dozen every year. In India, where malaria infected an estimated seventy-five million and killed eight hundred thousand every year, fatalities had dropped to zero by the early sixties. Between 1945 and 1965, DDT saved millions--even tens of millions--of lives around the world, perhaps more than any other man-made drug or chemical before or since.

What DDT could not do, however, was eradicate malaria entirely. How could you effectively spray eighty per cent of homes in the Amazonian jungle, where communities are spread over hundreds of thousands of highly treacherous acres? Sub-Saharan Africa, the most malarious place on earth, presented such a daunting logistical challenge that the eradication campaign never really got under way there. And, even in countries that seemed highly amenable to spraying, problems arose. "The rich had houses that they didn't want to be sprayed, and they were giving bribes," says Socrates Litsios, who was a scientist with the W.H.O. for many years and is now a historian of the period. "The inspectors would try to double their spraying in the morning so they wouldn't have to carry around the heavy tanks all day, and as a result houses in the afternoon would get less coverage. And there were many instances of corruption with insecticides, because they were worth so much on the black market. People would apply diluted sprays even when they knew they were worthless." Typical of the logistical difficulties is what happened to the campaign in Malaysia. In Malaysian villages, the roofs of the houses were a thatch of palm fronds called atap. They were expensive to construct, and usually lasted five years. But within two years of DDT spraying the roofs started to fall down. As it happened, the atap is eaten by caterpillar larvae, which in turn are normally kept in check by parasitic wasps. But the DDT repelled the wasps, leaving the larvae free to devour the atap. "Then the Malaysians started to complain about bedbugs, and it turns out what normally happens is that ants like to eat bedbug larvae," McWilson Warren said. "But the ants were being killed by the DDT and the bedbugs weren't--they were pretty resistant to it. So now you had a bedbug problem." He went on, "The DDT spray teams would go into villages, and no one would be at home and the doors would be locked and you couldn't spray the house. And, understand, for that campaign to work almost every house had to be sprayed. You had to have eighty-per-cent coverage. I remember there was a malaria meeting in '62 in Saigon, and the Malaysians were saying that they could not eradicate malaria. It was not possible. And everyone was arguing with them, and they were saying, 'Look, it's not going to work.' And if Malaysia couldn't do it--and Malaysia was one of the most sophisticated places in the region--who could?"

At the same time, in certain areas DDT began to lose its potency. DDT kills by attacking a mosquito's nervous system, affecting the nerve cells so that they keep firing and the insect goes into a spasm, lurching, shuddering, and twitching before it dies. But in every population of mosquitoes there are a handful with a random genetic mutation that renders DDT nontoxic--that prevents it from binding to nerve endings. When mass spraying starts, those genetic outliers are too rare to matter. But, as time goes on, they are the only mosquitoes still breeding, and entire new generations of insects become resistant. In Greece, in the late nineteen-forties, for example, a malariologist noticed Anopheles sacharovi mosquitoes flying around a room that had been sprayed with DDT. In time, resistance began to emerge in areas where spraying was heaviest. To the malaria warriors, it was a shock. "Why should they have known?" Janet Hemingway, an expert in DDT resistance at the University of Wales in Cardiff, says. "It was the first synthetic insecticide. They just assumed that it would keep on working, and that the insects couldn't do much about it." Soper and the malariologist Paul Russell, who was his great ally, responded by pushing for an all-out war on malaria. We had to use DDT, they argued, or lose it. "If countries, due to lack of funds, have to proceed slowly, resistance is almost certain to appear and eradication will become economically impossible," Russell wrote in a 1956 report. "TIME IS OF THE ESSENCE because DDT resistance has appeared in six or seven years." But, with the administrative and logistical problems posed by the goal of eighty-per-cent coverage, that deadline proved impossible to meet.

5.

In 1963, the money from Congress ran out. Countries that had been told they could wipe out malaria in four years--and had diverted much of their health budgets to that effort--grew disillusioned as the years dragged on and eradication never materialized. Soon, they put their money back into areas that seemed equally pressing, like maternal and child health. Spraying programs were scaled back. In those countries where the disease had not been completely eliminated, malaria rates began to inch upward. In 1969, the World Health Organization formally abandoned global eradication, and in the ensuing years it proved impossible to muster any great enthusiasm from donors to fund antimalaria efforts. The W.H.O. now recommends that countries treat the disease largely through the health-care system--through elimination of the parasite--but many anti-malarial drugs are no longer effective. In the past thirty years, there have been outbreaks in India, Sri Lanka, Brazil, and South Korea, among other places. "Our troubles with mosquitoes are getting worse," Spielman concludes in "Mosquito," "making more people sick and claiming more lives, millions of lives, every year."

For Soper, the unravelling of his dream was pure torture. In 1959, he toured Asia to check on the eradication campaigns of Thailand, the Philippines, Ceylon, and India, and came back appalled at what he had seen. Again and again, he found, countries were executing his strategy improperly. They weren't spraying for long enough. They didn't realize that unless malaria was ground into submission it would come roaring back. But what could he do? He had prevailed against gambiae in Brazil in the nineteen-thirties because he had been in charge; he had worked with the country's dictator to make it illegal to prevent an inspector from entering a house, and illegal to prevent the inspector from treating any open container of water. Jesse Hobbs tells of running into Soper one day in Trinidad, after driving all day in an open jeep through the tropical heat. Soper drove up in a car and asked Hobbs to get in; Hobbs demurred, gesturing at his sweaty shirt. "Son," Soper responded, "we used to go out in a day like this in Brazil and if we found a sector chief whose shirt was not wet we'd fire him." Killing mosquitoes, Soper always said, was not a matter of knowledge and academic understanding; it was a matter of administration and discipline. "He used to say that if you have a democracy you can't have eradication," Litsios says. "When Soper was looking for a job at Johns Hopkins--this would have been '46--he told a friend that 'they turned me down because they said I was a fascist.'" Johns Hopkins was right, of course: he was a fascist--a disease fascist--because he believed a malaria warrior had to be. But now roofs were falling down in Malaysia, and inspectors were taking bribes, and local health officials did not understand the basic principles of eradication--and his critics had the audacity to blame his ideas, rather than their own weakness.

It was in this same period that Rachel Carson published "Silent Spring," taking aim at the environmental consequences of DDT. "The world has heard much of the triumphant war against disease through the control of insect vectors of infection," she wrote, alluding to the efforts of men like Soper, "but it has heard little of the other side of the story--the defeats, the short-lived triumphs that now strongly support the alarming view that the insect enemy has been made actually stronger by our efforts." There had already been "warnings," she wrote, of the problems created by pesticides:

On Nissan Island in the South Pacific, for example, spraying had been carried on intensively during the Second World War, but was stopped when hostilities came to an end. Soon swarms of a malaria-carrying mosquito reinvaded the island. All of its predators had been killed off and there had not been time for new populations to become established. The way was therefore clear for a tremendous population explosion. Marshall Laird, who had described this incident, compares chemical control to a treadmill; once we have set foot on it we are unable to stop for fear of the consequences.

It is hard to read that passage and not feel the heat of Soper's indignation. He was familiar with "Silent Spring"--everyone in the malaria world was--and what was Carson saying?Of course the mosquitoes came back when DDT spraying stopped. The question was whether the mosquitoes were gone long enough to disrupt the cycle of malaria transmission. The whole point of eradication, to his mind, was that it got you off the treadmill: DDT was so effective that if you used it properly you could stop spraying and not fear the consequences. Hadn't that happened in places like Taiwan and Jamaica and Sardinia?

"Silent Spring" was concerned principally with the indiscriminate use of DDT for agricultural purposes; in the nineteen-fifties, it was being sprayed like water in the Western countryside, in an attempt to control pests like the gypsy moth and the spruce budworm. Not all of Carson's concerns about the health effects of DDT have stood the test of time--it has yet to be conclusively linked to human illness--but her larger point was justified: DDT was being used without concern for its environmental consequences. It must have galled Soper, however, to see how Carson effectively lumped the malaria warriors with those who used DDT for economic gain. Nowhere in "Silent Spring" did Carson acknowledge that the chemical she was excoriating as a menace had, in the two previous decades, been used by malariologists to save somewhere in the vicinity of ten million lives. Nor did she make it clear how judiciously the public-health community was using the chemical. By the late fifties, health experts weren't drenching fields and streams and poisoning groundwater and killing fish. They were leaving a microscopic film on the inside walls of houses; spraying every house in a country the size of Guyana, for example, requires no more DDT in a year than a large cotton farm does. Carson quoted a housewife from Hinsdale, Illinois, who wrote about the damage left by several years of DDT spraying against bark beetles: "The town is almost devoid of robins and starlings; chickadees have not been on my shelf for two years, and this year the cardinals are gone too; the nesting population in the neighborhood seems to consist of one dove pair and perhaps one catbird family. . . . 'Will they ever come back?' [the children]ask, and I do not have the answer." Carson then quoted a bird-lover from Alabama:"There was not a sound of the song of a bird. It was eerie, terrifying. What was man doing to our perfect and beautiful world?" But to Soper the world was neither perfect nor beautiful, and the question of what man could do to nature was less critical than what nature, unimpeded, could do to man. Here, from a well-thumbed page inserted in Soper's diaries, is a description of a town in Egypt during that country's gambiae invasion of 1943--a village in the grip of its own, very different, unnatural silence:

Most houses are without roofs. They are just a square of dirty earth. In those courtyards and behind the doors of these hovels were found whole families lying on the floor; some were just too weakened by illness to get up and others were lying doubled up shaking from head to foot with their teeth chattering and their violently trembling hands trying in vain to draw some dirty rags around them for warmth. They were in the middle of the malaria crisis. There was illness in every house. There was hardly a house which had not had its dead and those who were left were living skeletons, their old clothing in rags, their limbs swollen from undernourishment and too weak to go into the fields to work or even to get food.

It must have seemed to Soper that the ground had shifted beneath his feet--that the absolutes that governed his life, that countenanced even the most extreme of measures in the fight against disease, had suddenly and bewilderingly been set aside. "I was on several groups who evaluated malaria-eradication programs in some of the Central American countries and elsewhere," Geoffrey Jeffery recalls. "Several times we came back with the answer that with the present technology and effort it wasn't going to work. Well, that didn't suit Soper very much. He harangued us. We shouldn't be saying things like that!" Wilbur Downs, a physician who worked for the Rockefeller Foundation in Mexico in the fifties, used to tell of a meeting with Soper and officials of the Mexican government about the eradication of malaria in that country. Soper had come down from Washington, and amid excited talk of ending malaria forever Downs pointed out that there were serious obstacles to eradication--among them the hastened decomposition and absorption of DDT by the clays forming adobe walls. It was all too much for Soper. This was the kind of talk that was impeding eradication--the doubting, the equivocation, the incompetence, the elevation of songbirds over human life. In the middle of the meeting, Soper--ramrod straight, eyes afire--strode over to Downs, put both his hands around his neck, and began to shake.

6.

Fred Soper ran up against the great moral of the late twentieth century--that even the best-intentioned efforts have perverse consequences, that benefits are inevitably offset by risks. This was the lesson of "Silent Spring," and it was the lesson, too, that malariologists would take from the experience with global eradication. DDT, Spielman argues, ought to be used as selectively as possible, to quell major outbreaks. "They should have had a strong rule against spraying the same villages again and again," he says. "But that went against their doctrine. They wanted eighty-per-cent coverage. They wanted eight out of ten houses year after year after year, and that's a sure formula for resistance." Soper and Russell once argued about whether, in addition to house spraying, malaria fighters should continue to drain swamps. Russell said yes; Soper said no, that it would be an unnecessary distraction. Russell was right: it made no sense to use only one weapon against malaria. Spielman points out that malaria transmission in sub-Saharan Africa is powerfully affected by the fact that so many people live in mud huts. The walls of that kind of house need to be constantly replastered, and to do that villagers dig mud holes around their huts. But a mud hole is a prime breeding spot for gambiae. If economic aid were directed at helping villagers build houses out of brick, Spielman argues, malaria could be dealt a blow. Similarly, the Princeton University malariologist Burton Singer says that since the forties it has been well known that mosquito larvae that hatch in rice fields--a major breeding site in southeast Asia--can be killed if the water level in the fields is intermittently drained, a practice that has the additional effect of raising rice yields. Are these perfect measures? No. But, under the right circumstances, they are sustainable. In a speech Soper presented on eradication, he quoted Louis Pasteur: "It is within the power of man to rid himself of every parasitic disease." The key phrase, for Soper, was "within the power." Soper believed that the responsibility of the public-health professional was to make an obligation out of what was possible. He never understood that concessions had to be made to what was practical. "This is the fundamental difference between those of us in public health who have an epidemiological perspective, and people, like Soper, with more of a medical approach," Spielman says. "We deal with populations over time, populations of individuals. They deal with individuals at a moment in time. Their best outcome is total elimination of the condition in the shortest possible period. Our first goal is to cause no outbreaks, no epidemics, to manage, to contain the infection." Bringing the absolutist attitudes of medicine to a malarious village, Spielman says, "is a good way to do a bad thing." The Fred Soper that we needed, in retrospect, was a man of more modest ambitions.

But, of course, Fred Soper with modest ambitions would not be Fred Soper; his epic achievements arose from his fanaticism, his absolutism, his commitment to saving as many lives as possible in the shortest period of time. For all the talk of his misplaced ambition, there are few people in history to whom so many owe their lives. The Global Malaria Eradication Programme helped eliminate the disease from the developed world, and from many parts of the developing world. In a number of cases where the disease returned, it came back at a lower level than it had been in the prewar years, and even in those places where eradication made little headway the campaign sometimes left in place a public infrastructure that had not existed before. The problem was that Soper had raised expectations too high. He had said that the only acceptable outcome for Global Eradication was global eradication, and when that did not happen he was judged--and, most important, he judged himself--a failure. But isn't the urgency Soper felt just what is lacking in the reasonableness of our contemporary attitude--in our caution and thoughtfulness and restraint? In the wake of the failure of eradication, it was popular to say that truly effective malaria control would have to await the development of a public-health infrastructure in poorer countries. Soper's response was, invariably: What about now? In a letter to a friend, he snapped, "The delay in handling malaria until it can be done by local health units is needlessly sacrificing the generation now living." There is something to admire in that attitude; it is hard to look at the devastation wrought by H.I.V. and malaria and countless other diseases in the Third World and not conclude that what we need, more than anything, is someone who will marshal the troops, send them house to house, monitor their every movement, direct their every success, and, should a day of indifference leave their shirts unsullied, send them packing. Toward the end of his life, Soper, who died in 1975, met with an old colleague, M. A. Farid, with whom he had fought gambiae in Egypt years before. "How do things go?" Soper began. "Bad!" Farid replied, for this was in the years when everyone had turned against Soper's vision. "Who will be our ally?" Soper asked. And Farid said simply, "Malaria," and Soper, he remembered, almost hugged him, because it was clear what Farid meant: Someday, when DDT is dead and buried, and the West wakes up to a world engulfed by malaria, we will think back on Fred Soper and wish we had another to take his place.


229 posted on 08/28/2005 8:19:32 PM PDT by WildTurkey (When will CBS Retract and Apologize?)
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To: ml1954

How do you know it was?


230 posted on 08/28/2005 8:20:05 PM PDT by killermosquito (Buffalo is what you get when liberalism runs its course.)
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To: Coyoteman
People are intense because this is a serious subject. The CS/ID folks are using a lie (i.e., that ID is not religiously based) to wedge (and mandate) the study of the bible into public schools (e.g., Kansas).

The validity of a theory does not depend one iota on the motivations of its proponents. It depends only on the facts.

The claim that ID is false because it is "religiously based" is as nonsensical as the claim that the Theory of Evolution is false because it is "athiestically based."

Like so many arrogant evolutionists, you don't know nearly as much as you think you do about how science is supposed to work.

231 posted on 08/28/2005 8:20:59 PM PDT by RussP
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To: killermosquito

You made a statement of fact and now you can't back it up. Typical. About the 25 time a creo has posted a 'fact' and when asked to prove their fact, they come back with some obtuse retort.


232 posted on 08/28/2005 8:21:32 PM PDT by WildTurkey (When will CBS Retract and Apologize?)
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To: RussP
The claim that ID is false because it is "religiously based" is as nonsensical as the claim that the Theory of Evolution is false because it is "athiestically based." Like so many arrogant evolutionists, you don't know nearly as much as you think you do about how science is supposed to work.

Who claims ID is false because it is "religiously based"? Please cite.

233 posted on 08/28/2005 8:24:01 PM PDT by WildTurkey (When will CBS Retract and Apologize?)
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To: killermosquito
I have all the evidence I need and wear my creationist badge with pride.
234 posted on 08/28/2005 8:26:43 PM PDT by WildTurkey (When will CBS Retract and Apologize?)
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To: ml1954

Macro evolution is an extension of micro evolution and is at the center of the evolution debate. I never said it was a separate theory. Not sure how you arrived at that.


235 posted on 08/28/2005 8:27:14 PM PDT by plain talk
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To: RussP
Like so many arrogant evolutionists, you don't know nearly as much as you think you do about how science is supposed to work.

Fact: ID is not based on science.

Fact: ID is being used by creationists in an effort to discredit evolutionary theory.

Fact: creos post dumb posts.

236 posted on 08/28/2005 8:28:20 PM PDT by WildTurkey (When will CBS Retract and Apologize?)
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To: Oztrich Boy
Dr. George Wald, "Nobel Prize winner in Biology" never said it.

It gets worse: there is no "Nobel Prize .... in Biology."

That's the problem with anti-Evo quote fabrication; the Devil is in the details!

237 posted on 08/28/2005 8:28:24 PM PDT by longshadow
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To: killermosquito

How do you know it was?

I didn't say it was. I say I don't know. You made an unequivocal statement that it wasn't by chance.

So I repeat, how do you know?

238 posted on 08/28/2005 8:28:36 PM PDT by ml1954
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To: killermosquito
How do you know it was?

I didn't say it was. I say I don't know. You made an unequivocal statement that it wasn't by chance.

So I repeat, how do you know?

239 posted on 08/28/2005 8:30:53 PM PDT by WildTurkey (When will CBS Retract and Apologize?)
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To: WildTurkey

Fact: claiming something to be a fact does not make it a fact.

Fact: many evos don't seem to understand that fact.


240 posted on 08/28/2005 8:35:34 PM PDT by RussP
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