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Darwin's greatest challenge tackled
European Molecular Biology Laboratory ^ | 10/28/2004 | EMBL

Posted on 11/03/2004 5:11:47 PM PST by general_re

Darwin's greatest challenge tackled
The mystery of eye evolution

Researchers provide concrete evidence about how the human eye evolved

When Darwin's skeptics attack his theory of evolution, they often focus on the eye. Darwin himself confessed that it was 'absurd' to propose that the human eye, an 'organ of extreme perfection and complication' evolved through spontaneous mutation and natural selection. But he also reasoned that "if numerous gradations from a simple and imperfect eye to one complex and perfect can be shown to exist" then this difficulty should be overcome. Scientists at the European Molecular Biology Laboratory [EMBL] have now tackled Darwin's major challenge in an evolutionary study published this week in the journal Science. They have elucidated the evolutionary origin of the human eye.

Researchers in the laboratories of Detlev Arendt and Jochen Wittbrodt have discovered that the light-sensitive cells of our eyes, the rods and cones, are of unexpected evolutionary origin ­ they come from an ancient population of light-sensitive cells that were initially located in the brain.

"It is not surprising that cells of human eyes come from the brain. We still have light-sensitive cells in our brains today which detect light and influence our daily rhythms of activity," explains Wittbrodt. "Quite possibly, the human eye has originated from light-sensitive cells in the brain. Only later in evolution would such brain cells have relocated into an eye and gained the potential to confer vision."

The scientists discovered that two types of light-sensitive cells existed in our early animal ancestors: rhabdomeric and ciliary. In most animals, rhabdomeric cells became part of the eyes, and ciliary cells remained embedded in the brain. But the evolution of the human eye is peculiar ­ it is the ciliary cells that were recruited for vision which eventually gave rise to the rods and cones of the retina.

So how did EMBL researchers finally trace the evolution of the eye?

By studying a 'living fossil,' Platynereis dumerilii, a marine worm that still resembles early ancestors that lived up to 600 million years ago. Arendt had seen pictures of this worm's brain taken by researcher Adriaan Dorresteijn [University of Mainz, Germany]. "When I saw these pictures, I noticed that the shape of the cells in the worm’s brain resembled the rods and cones in the human eye. I was immediately intrigued by the idea that both of these light-sensitive cells may have the same evolutionary origin."

To test this hypothesis, Arendt and Wittbrodt used a new tool for today’s evolutionary biologists – 'molecular fingerprints'. Such a fingerprint is a unique combination of molecules that is found in a specific cell. He explains that if cells between species have matching molecular fingerprints, then the cells are very likely to share a common ancestor cell.

Scientist Kristin Tessmar-Raible provided the crucial evidence to support Arendt's hypothesis. With the help of EMBL researcher Heidi Snyman, she determined the molecular fingerprint of the cells in the worm's brain. She found an opsin, a light-sensitive molecule, in the worm that strikingly resembled the opsin in the vertebrate rods and cones. "When I saw this vertebrate-type molecule active in the cells of the Playtnereis brain – it was clear that these cells and the vertebrate rods and cones shared a molecular fingerprint. This was concrete evidence of common evolutionary origin. We had finally solved one of the big mysteries in human eye evolution."

Source Article
Ciliary photoreceptors with vertebrate-type opsins in an invertebrate brain.
D. Arendt, K. Tessmar-Raible, Snyman, Dorresteijn, J. Wittbrodt
Science. October 29, 2004.


TOPICS: Culture/Society; News/Current Events; Philosophy
KEYWORDS: crevolist; darwin; evolution; eye; sight
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To: Texas Songwriter
Mr. Dimensio, in rereading your remarks I focused on the phrase "rational thought". I wonder, can you explain to me from a scientific reference point, of course, what is thought

Thought is the perceived end-result of various chemical reactions within the brain.

how do you measure it?

The reactions themselves can be observed, though I'm not sure that a unit of measurement can apply to them.

where does it reside,,does it exist?

Within the brain. I pontificate, can thought be "rational"? Yes.

What has this to do with the fact that nothing that you presented is a logical argument, and some of it is in fact an attempt to distract from the fact that I was exposing logical fallacies?
121 posted on 11/07/2004 8:16:42 PM PST by Dimensio (Join the Monthly Internet Flash Mob: http://www.aa419.org)
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To: Dimensio
Jesus Christ offers the gift of eternal salvation and has stated that He is the way, the truth and the life, and that no man can come to God the Father except by Him (Jesus Christ). If you have difficulty with the God-Man, Jesus Christ, then you must take it up with Him. If you deny Him, He says that He will deny you before the Father.

Is there empirical evidence to explain it all? Yes. Jesus Christ is the evidence of things not seen. He transcended space and time in order to save us. All he wants is for us to accept the gift of salvation He offers. In order to accept Him as our Savior and Lord, we must first recognize that we are not the center of the universe, He is. Coming to grips with our own mortality and finiteness is impossible without His aid.

Jesus Christ said to Saul of Tarsus, "Saul, Saul, why persecutest thou me? it is hard for thee to kick against the pricks." Acts 26:14

All of my preaching is worthless, because I was not converted by preaching but by Jesus Christ's love for me. Seek Him out with all sincerity and He will reveal Himself to you. He loves you so much that He died for You. He wants to share His kingdom with You. I may sound like a nut, but what have you to lose by just seeking Him out?

I offer you a challenge. Tonight, before you go to sleep, kneel next to your bed, or in a closet, or wherever and with your eyes closed just call on the name of Jesus Christ and ask Him to reveal Himself to you. I am not saying He will appear in your presence, although He may (I don't know anyone living who has had such an experience), but the real work He accomplishes is on the inside of us. We are much more than flesh and bone, and it is the inner man who lives inside this coat of flesh that He wants to change. What have you to lose? And if the words of Jesus Christ are true, think what you have to gain.

122 posted on 11/07/2004 8:21:21 PM PST by O.C. - Old Cracker (When the cracker gets old, you wind up with Old Cracker. - O.C.)
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To: Dimensio

Did you say the brain perceives neurochemical reactions in the brain? That is not an adequet explaination. I do not measure it. They can be observed...I assume you refer to electroencephalography and the various types of wave forms that exist. I still do not know this to be thought. Could you explain this to me please. And no, it was just an after thought. I origianally asked to be your student and have you instruct me as to origins and the laws of thermodynamics, scientific facts which I feel both you and I can stipulate are observable and reproducible scientific dictums. I was not trying to distract you.


123 posted on 11/07/2004 8:23:31 PM PST by Texas Songwriter (Texas Songwriter)
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To: general_re

Is the solar system a closed system? How about the Milky Way? How about this constellation? How about the universe?


124 posted on 11/07/2004 8:25:21 PM PST by Texas Songwriter (Texas Songwriter)
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To: Dimensio
How do you know that the Bible is accurate.

The reliability of the Bible

Another historical test.

Clemson link

125 posted on 11/07/2004 8:26:51 PM PST by Tribune7
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To: general_re

Where did that big hot thing in sky come from?


126 posted on 11/07/2004 8:29:29 PM PST by Texas Songwriter (Texas Songwriter)
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To: Texas Songwriter
Is the solar system a closed system?

No, though the overall energy input into the system is so small that it can be reasonably approximated to one.

How about the Milky Way?

Same as the solar system. How about this constellation?

What constellation? Do you even understand the subject?

How about the universe?

As far as can be determined, the universe is a truly closed system.

None of this has anything to do with the fact that evolution does not violate the second law of thermodynamics.
127 posted on 11/07/2004 8:30:39 PM PST by Dimensio (Join the Monthly Internet Flash Mob: http://www.aa419.org)
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To: O.C. - Old Cracker
I offer you a challenge. Tonight, before you go to sleep, kneel next to your bed, or in a closet, or wherever and with your eyes closed just call on the name of Jesus Christ and ask Him to reveal Himself to you.

I've been offered this challenge before. It didn't do anything then, and I suspect that it won't do anything now, but I'll humour you and try it.

Nothing that you said amounts to anything beyond assertion. You haven't given me any reason why I should take your word regarding the nature of the divine over that of a Hindu.
128 posted on 11/07/2004 8:32:43 PM PST by Dimensio (Join the Monthly Internet Flash Mob: http://www.aa419.org)
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To: general_re

Here's a bit of evolutionary history about Darwin. Englishmen evolved from a piece French mold.


129 posted on 11/07/2004 8:37:51 PM PST by pypo (I support our troops' Commander-in-Chief)
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To: Dimensio

Please explain what was going on before life began on earth. Go back, I believe you say 5.5 billion years, and take me back from there. Before organic evolution began. I am confused as you can see.


130 posted on 11/07/2004 8:39:03 PM PST by Texas Songwriter (Texas Songwriter)
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To: eleni121
Radiometric Dating A Christian Perspective
131 posted on 11/07/2004 8:42:28 PM PST by Doctor Stochastic (Vegetabilisch = chaotisch is der Charakter der Modernen. - Friedrich Schlegel)
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To: Texas Songwriter
How about the universe?

Technically, that's the only one you listed that is a closed system. Of course, nothing precludes local decreases in entropy even in closed systems.

Where did that big hot thing in sky come from?

Here you go...

132 posted on 11/07/2004 8:42:50 PM PST by general_re (Drive offensively - the life you save may be your own.)
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To: general_re

So we agree that the 1st law of thermodynamics is truth. But then you just made an exception to the fact of the law of entropy. I simply adhere to observable science and you adjust you "facts" which are not observable nor reproducible. That is faith. You are so entitled to your faith, but you are not entitled to dispose of the 1st and 2nd laws of thermodynamics apart from your faith or metaphysics.


133 posted on 11/07/2004 8:47:39 PM PST by Texas Songwriter (Texas Songwriter)
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To: Texas Songwriter
But then you just made an exception to the fact of the law of entropy.

No, he didn't. Your understanding is faulty.
134 posted on 11/07/2004 8:50:36 PM PST by Dimensio (Join the Monthly Internet Flash Mob: http://www.aa419.org)
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To: general_re; Ships of Wood, Men of Iron

Bump

Thought you might find this interesting.


135 posted on 11/07/2004 8:50:42 PM PST by NYTexan
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To: Dimensio

He is not required to give you evidence of his assertion. He asserts he takes his belief on faith, evidence not seen. You,however, have risen above these lowly levels to assert the holy grail of science, which we all agree require evidence. So please spell it out scientifically for Mr. Ole Cracker and me. We are not as enlightened as you. We await your reply.


136 posted on 11/07/2004 8:52:19 PM PST by Texas Songwriter (Texas Songwriter)
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To: Texas Songwriter
So we agree that the 1st law of thermodynamics is truth.

Ummm, well, I was talking about the second law, not the first - the first law merely states that energy is conserved, and doesn't directly implicate entropy. Did you want to take a moment to review before continuing?

137 posted on 11/07/2004 8:52:38 PM PST by general_re (Drive offensively - the life you save may be your own.)
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To: Dimensio

I believe he stated that the universe was the only closed system. He then stated the Law of entropy did not apply universally to it. That is an exception to the rule or to the law of entropy.


138 posted on 11/07/2004 8:55:10 PM PST by Texas Songwriter (Texas Songwriter)
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To: general_re

You are correct. I incorrectly prescribed the 1st law and meant to say the 2nd law (entropy). Thank you. See we can be nice.


139 posted on 11/07/2004 8:57:20 PM PST by Texas Songwriter (Texas Songwriter)
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To: Texas Songwriter
So you're saying that you're exempt from providing evidence because you're discussing religion? That you get to make all of the assertions that you want and they are to be accepted without evidence simply because you say so?

Sorry. You're trying to redefine the terms to suit a dishonest agenda. You merely spelled out why Ole Cracker's point was totally unconvincing.
140 posted on 11/07/2004 9:00:47 PM PST by Dimensio (Join the Monthly Internet Flash Mob: http://www.aa419.org)
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