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Mo'Nique Breaks Down in Tears Warning Fans About GLP-1 Weight-Loss Drugs: 'What Are the Long-Term Effects?'
OK Magazine ^ | Feb. 23 2026 | Olivia Salamone

Posted on 02/27/2026 10:20:03 AM PST by nickcarraway

Mo'Nique urged fans to think twice before jumping on the latest weight-loss trend.

In an emotional video shared online, the actress and comedian became visibly teary as she spoke directly to viewers about the growing popularity of GLP-1 medications.

Mo'Nique Questioned GLP-1's Long-Term Effects

Tap Here To Add Ok Magazine as A Trusted SourceAdd Ok Magazine as A Trusted Source on Google image of Mo'Nique shared an emotional message about the risks of GLP-1 weight-loss drugs. Source: mega Mo'Nique shared an emotional message about the risks of GLP-1 weight-loss drugs.

The drugs, which are commonly prescribed to help regulate blood sugar and support weight loss, have surged in demand, particularly as high-profile celebrities openly discuss their use.

But Mo'Nique made it clear she has serious concerns.

"What [are] the long-term effects? What will it do to your body? Your mind? What will it do to us five years from now, 10 years from now?" she asked, according to Essence, questioning whether people fully understand what they're putting into their systems.

“Love yourself enough not to be tricked.”

Mo'Nique warns people about the dangers of taking weight loss drugs and encourages people to research what they’re putting in their body.

She questioned what it will do to your mind and body.

While acknowledging that many users may be thrilled with their physical transformations, she cautioned that short-term results don't always guarantee long-term safety.

"You may get down to that size two or size four or that size eight or whatever that thing is. But I would ask you to research what you're putting in your body," she said.

The Oscar winner also suggested that social media and celebrity culture are influencing people to follow suit.

"They got us caught up in trends," Mo'Nique said, adding that ordinary individuals are being swayed by "big stars."


TOPICS: Food; Health/Medicine
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To: nickcarraway

Of course, no one should take any drug without consulting with a doctor that knows you AND doing some research on your own.

A lot of the stuff you read on line about GLP-1s would have you believe that these drugs are “new.” They are not. They have been around for a long time. The long term affects have been examined.

Of course, with so many people taking them (those who should and a lot who shouldn’t) the medical field is finding a lot of other areas where these drugs have an impact.

Finally, a lot of the people jumping on this bandwagon without doing the research try to continue eating in the way that got them in trouble beforehand. That will cause digestive issues. And in the end, the weight loss will not be maintainable.

The proper use of these drugs will allow a person to “relearn” how to eat properly. This is the unspoken “Part B.” If you do Part A and ignore Part B…the drug will fail you.

If you do both, its still a lifelong change that will slip if you take your eyes off it for a second.


21 posted on 02/27/2026 11:09:16 AM PST by Vermont Lt
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To: nickcarraway

My wife has reached perfect body weight and blood sugar A1C by using the low carb Adkins diet with minor modifications.


22 posted on 02/27/2026 11:09:26 AM PST by KC Burke
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To: nickcarraway

My doctor keeps trying to put me on those. I have type 2 diabetes and am morbidly obese (fat).

NO THANKS!

You have to take them for the rest of your life. (BIG Pharma LOVE’S THAT)

You have to wear a monitor to measure your sugar constantly so they can adjust your meds right away because they don’t really know how much to reduce your insulin.

These are relatively new drugs and they can’t yet know the long term side effects.

I say STAY AWAY from these drugs. Not worth the risk.


23 posted on 02/27/2026 11:33:14 AM PST by faucetman (Just the facts, ma'am, Just the facts )
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To: nickcarraway

She seems like a nice lady and very brave. I can’t find a single instance of her attacking Trump. Oprah and Lee Daniels and the Black Mafia were horrible to her, trying to control her and rip her off, and she went public about it, hurting her career. She is 100% right about these drugs.


24 posted on 02/27/2026 11:45:04 AM PST by montag813
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To: nickcarraway

Current Use of GLP-1 Drugs
General Statistics

Approximately 12% of adults in the U.S. are currently taking a GLP-1 drug.
This translates to about 30 million adults, given the U.S. adult population.


25 posted on 02/27/2026 12:00:53 PM PST by central_va (I won't be reconstructed and I do not give a damn... )
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To: faucetman
My doctor keeps trying to put me on those. I have type 2 diabetes and am morbidly obese (fat).

NO THANKS!

I'm not trying to berate you, but think about this for a second. You're morbidly obese and have type 2 diabetes, the combination which almost guarantees you an early grave. Do you know any old, fat people with type 2 diabetes? Me neither.

GLP-1 agonists are not new, they've been around a long time and are well studied. Millions of people have taken them for years and the results are almost universally positive, a lot of people are alive today because they've lost significant amounts of weight using them that prevented heart attacks, strokes, diabetes, etc. There are some side effects but they're generally mild and easily handled.

It's your life and you can do what you want with it. If I was in a position where metaphorically I was in a car about to careen off a cliff I'd certainly try something to fix the situation, especially if it was a drug like these with good track records. Do you honestly think there's anywhere near the risk from using a GLP-1 that there is from remaining morbidly obese with type 2 diabetes? That's just illogical, bordering on crazy.

26 posted on 02/27/2026 12:06:19 PM PST by GaryCrow
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To: nickcarraway

we were just discussing this very issue this morning, wondering how many years from now that GLP-1s will be discovered to be the Nuevo Phen-Fen disaster ...


27 posted on 02/27/2026 12:07:52 PM PST by catnipman ((A Vote For The Lesser Of Two Evils Still Counts As A Vote For Evil))
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To: 1FreeAmerican

the issue that scares me the most about GLP-1s is the possibility of long-term gastroparesis AFTER GLP-1 consumption has ceased ...

[i know someone who developed that condition (not from GLP-1s), and it almost destroyed her life] ...


28 posted on 02/27/2026 12:11:45 PM PST by catnipman ((A Vote For The Lesser Of Two Evils Still Counts As A Vote For Evil))
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To: Sarah Barracuda

“I hear it can cause your stomach to stop working”

yep, and it’s called gastroparesis ...


29 posted on 02/27/2026 12:13:48 PM PST by catnipman ((A Vote For The Lesser Of Two Evils Still Counts As A Vote For Evil))
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To: Opinionated Blowhard

I have been on Monjouro for about 4 years now. Lost 55+ pounds so far, blood sugars under good control, no side effects that I am aware of, feel better than I did 10 years ago.


30 posted on 02/27/2026 12:24:12 PM PST by TheConservator
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To: TheConservator

Dont take this the wrong way but I have a question for you. You must eat a lot less. The amount you spend at the grocery store significantly less than before taking Glp1s?


31 posted on 02/27/2026 12:29:47 PM PST by central_va (I won't be reconstructed and I do not give a damn... )
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To: Sarah Barracuda

I take Mounjaro. It’s principle effect is to shrink your stomach. In my case, I take it before bed Friday night, the effect is kicking in by about 12 hours later, and peaks about 24-28 hours later.

What this means is that if I stuff myself Saturday evening, I will feel nauseous and possibly vomit in the wee hours Sunday morning—because I have eaten more food than my now shrunken stomach can hold.

The solution is simple. Don’t eat a lot on Saturday, and particularly for dinner. I will either have a salad, or perhaps a few slices of deli roast beef and a little cottage cheese. As long as you don’t eat an amount that exceeds your (smaller) stomach capacity, you don’t get side effects.

I figured that out within a month or two of when I first started taking it (about 4 years ago) and have had no issues since.


32 posted on 02/27/2026 12:37:53 PM PST by TheConservator
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To: central_va

As before, I eat when I feel hungry. I just don’t feel hungry as much. I do think I eat a bit healthier than before though.


33 posted on 02/27/2026 12:48:44 PM PST by TheConservator
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To: GaryCrow

Agree 100%


34 posted on 02/27/2026 12:51:30 PM PST by TheConservator
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To: nickcarraway

A lot of people want these drugs so they don’t have to change their eating habits. Recently diagnosed pre diabetic, Type II and I’ve lost 40 lbs thru Keto. I’ll have a cheat once in awhile but really have changed my eating habits. I had sushi for lunch the other and ran into my highest spike in spite of only eating half so now I know if I go to a sushi joint, I’ll have a salad with chicken.

I’ve recommended to people to try wearing a glucose meter. You can buy one on Amazon without a prescription & it gives you so much insight into your health. I was freaking out over a 272 reading but can’t imagine what it was when I ate a cheeseburger, fries & a dessert. Its also given me insight into my moods when my glucose runs high and low.


35 posted on 02/27/2026 12:55:05 PM PST by Mean Daddy (Who will do the Democrat voting that Americans won’t do? - rightwingcrazy)
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To: Opinionated Blowhard

The Selena monsta is now a skinnier monsta.


36 posted on 02/27/2026 12:56:09 PM PST by PIF (They came for me and mine ... now its your turn)
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To: catnipman

My sister has that condition its HORRIBLE..she didnt get it from taking any weight loss drug it just happened to her and basically the doc told her if she were to ever get the stomach flu her stomach would stop working so every time she hears about one of her kids being exposed to stomach flu in school she panics


37 posted on 02/27/2026 1:09:31 PM PST by Sarah Barracuda
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To: TexasFreeper2009

i was wondering what she had said about the covid vaccine also


38 posted on 02/27/2026 1:43:55 PM PST by wafflehouse ("there was a third possibility that we hadn't even counted upon" -Alice's Restaurant Massacree)
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To: faucetman

I was on mounjaro for several months. I can no longer afford it, but it got my A1c’s down to 5.9, where they have remained, even though I regained some of the weight. I did not even think of food while I was on it. If the price comes down where I can afford it, I will go on it again, until I’m closer to my ideal weight. I’m 74. Old people need to carry some extra weight, in case they get sick. I’m not trying to get skinny, just lose some fat.


39 posted on 02/27/2026 2:56:00 PM PST by Flaming Conservative ((Pray without ceasing))
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To: nickcarraway

I did read the article but she didn’t seem to say why she was crying?

Frankly, as opposed to any kind of drugs even OTC things, I’ve been considering microdosing terzepitide - Zepbound.

Since 1987 I have been fighting my weight after a pituitary tumor and lots of endocrine damage. Before I die I’d like to get into my Zena disco jeans.

No, really.


40 posted on 02/27/2026 3:02:33 PM PST by CaptainPhilFan (God gave them over to a depraved mind, to do things which are improper and repulsive, Rom 1:28)
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