Posted on 01/17/2026 9:00:27 PM PST by ConservativeMind
"What should I eat?" is perhaps the most common question patients with inflammatory bowel disease ask their doctors.
Now, new research provides one potential answer. Their national, randomized controlled clinical trial found that a short-term, calorie-restrictive diet significantly improved both physical symptoms and biological indicators of mild-to-moderate Crohn's disease.
The findings were notable, demonstrating significant declines in objective markers of inflammation in biologic samples alongside improvements in clinical symptoms.
The study compared the symptoms and biological indicators of patients with mild-to-moderate Crohn's disease as they either followed a fasting mimicking diet or ate their normal diet for three consecutive months.
Participants in the fasting mimicking group severely limited their calories for five consecutive days per month, eating between about 700 and 1,100 calories a day, Sinha said. Plant-based meals were provided during the fasting period. For the remainder of the month, the fasting mimicking group ate their normal diet.
At the end of the study, about two-thirds of the fasting mimicking group experienced improvement in their symptoms.
In the control group, less than half experienced improvements in their symptoms. The improvement was likely a result of natural symptom fluctuations and taking medications.
Sinha was inspired to study the fasting mimicking diet in patients with Crohn's disease after earlier research indicated the diet could reduce levels of C-reactive protein, a common marker of systemic inflammation.
Along with tracking participants' clinical response and remission, the researchers also explored changes in biological specimens.
The researchers found a significant decline in fecal calprotectin, a protein in the stool that indicates gut inflammation, in the fasting mimicking group compared with the control group. Some inflammation-promoting lipid mediators derived from fatty acids also declined in fasting mimicking group participants.
Similarly, the immune cells of fasting mimicking group participants produced fewer of several types of inflammatory molecules.
(Excerpt) Read more at medicalxpress.com ...
My wife and I have done this exact diet, packaged from Prolon (ProlonLife.com). We did it to get rid of defective cells and proteins, while revving up stem cells to go out and fix whatever our body can find to address. Doing this diet three times reduces your biological age by 2.5 years.
We have found multiple personal benefits and are sold on doing it at least three or four times a year.
We can’t recommend it more highly.
One friend of ours with Crohn’s Disease has already been put on this diet, as of last week, with the study I got a few weeks back, which she gave to her doctor.
I should be super healthy then as ive onky ever eaten just 2 meals a day, brunch and dinner. And its not many calories. A ham egg bacon cheese sandwhich for brea,fsst with cup of coffee, and a soda (though ,ateely been eating an orange too, they are pretty gpod right now). Then nothing till dinner which usua,,y is about an 8 ounce steak or chop or chicken, maybe a veggie, or a potatoe, and later in the evening a soda. Might ssitch it up once in awhile with pasta, or boiled dinner, or tomatoe sandwhich, but usually stick to some type of meat for dinner.
Im thinking the czlories cznt be that high. (Never counted them) Been 170-190 lbs for 40 years cept when real sick, then i lose z lot. Basically its kindz like a fasting diet id guess?
This is really stupid - and dangerous - research.
It’s been known for years that dietary intake directly affects the gut and later found that dysbiosis of the gut is a direct contributary factor for CD, which is just one of multiple conditions resulting from a diseased gut.
Fasting intermittently without a major overhaul of dietary habits merely fosters a diseased state.
There is a reason I frame ‘diet’ as a 4-letter word among the rest of the vulgarities.
The big benefits come from autophagy and the stem cell generation it creates. Autophagy is a phase in which cells finally can seek and destroy defective proteins and cells for use or for reconstruction into new, needed material.
Intermittent fasting doesn't achieve this until the 3rd day of a fast.
Prolon does this safely.
Thanks ill check that out. I did go on a “Semi-elemental xiet” for z little over 3 months. Stzyed true to it, hoping,to give everything a break. Its basically “predigested food drink” so that the body doesnt have to work so hard breaking down the nutrients. And supplimented with mtc oil, coconut oil, and something ekse i cant recsll right now.
Got pretty intense. Id stsnd up from sitting position and go to walk, and take a few steps znd black out. Think it was a sugar thing, but not sure. Happened almost every time. Got so id make it to the living room door, amd prop myself up till the head rush resolved. Which was only about 15-20 seconds or so.
It was tough, but i did it. Didnt feel any better unfortunetly. Mighta had a little more stamina, but nothing to write home about. The stuff i took was Absorb plus, and was about $70 for a czn which didnt last long. It was pretty expensive.
“Plant-based meals were provided during the fasting period.”
These kind of garbage junk science, typical of the nutrition field, is not only dangerous and confusing, it’s a deflection from the real cure. We KNOW Krohn disease and other IBS diseases can be cured in weeks by a high fat, no plants, strictly carnivore diet.
“We KNOW Krohn disease and other IBS diseases can be cured in weeks by a high fat, no plants, strictly carnivore diet.”
The BIG PROBLEM with that diet is that it doesn’t require drugs or medical supervision.
“The BIG PROBLEM with that diet is that it doesn’t require drugs or medical supervision.”
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