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Nasal Spray May Reduce Risk Of COVID-19 Infection: Study
Epoch Times ^ | 09/05/2025 | Zachary Steiber

Posted on 09/05/2025 8:05:11 PM PDT by SeekAndFind

A nasal spray typically used to relieve allergy symptoms may help combat COVID-19, according to a new study.

People who received the azelastine nasal spray in a randomized, placebo-controlled trial in Germany were less likely to test positive for COVID-19, researchers reported on Sept. 2.

Only 5 participants administered the spray had laboratory-confirmed COVID-19, compared to 15 in the placebo group, they said.

Spray recipients also had a lower incidence of rhinovirus infections.

The single-center trial involved 450 people receiving the spray or a placebo three times a day for 56 days. The trial lasted from March 2023 to July 2024.

Azelastine nasal spray could provide an additional easily accessible prophylactic to complement existing protective measures, especially for vulnerable groups, during periods of high infection rates, or before travelling,” Dr. Robert Bals, professor of internal medicine at Saarland University, who led the trial, said in a statement.

In a commentary article, also published by JAMA Internal Medicine, U.S. researchers Dr. Samuel Vidal and Dr. Dan Barouch said that the German scientists reported “promising data.”

Since the trial was carried out at one center and had a relatively modest size, further studies are needed to assess whether the spray is actually effective against COVID-19, Bals and his co-authors said.

“These findings support the potential of azelastine as a safe prophylactic approach warranting confirmation in larger, multicentric trials,” they wrote.

The trial was funded by URSAPHARM Arzneimittel GmbH, which manufactures the spray, and some of the authors are employees of the company.

In the United States, azelastine was approved in 2012 to reduce symptoms of seasonal allergies. It is sold as Dymista and is also available generically. Side effects include drowsiness and headache.

Earlier Findings

Some earlier papers have also indicated that the spray works against seasonal viruses.

In a trial carried out in India that involved some of the same German researchers, neither arm had COVID-19-related hospitalizations, but recipients of azelastine had lower viral loads and improved symptoms, the researchers said in a 2024 paper.

People who tested positive for COVID-19 and received the antihistamine had lower viral loads than placebo recipients, researchers, including some of the authors of the new paper, said in a 2023 paper. The trial was conducted in Germany.

Both of those trials were funded by URSAPHARM.

Scientists said in 2022 that a study indicated that azelastine reduced the effects of COVID-19 in vitro, or in a laboratory setting. The study received funding from CEBINA GmbH, a partner of URSAPHARM.


TOPICS: Health/Medicine; Science; Society
KEYWORDS: covid; nasalspray

1 posted on 09/05/2025 8:05:11 PM PDT by SeekAndFind
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To: SeekAndFind

Have they developed a definitive test for covid yet?


2 posted on 09/05/2025 8:17:28 PM PDT by SuzyQue
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To: SuzyQue

Jut keep your mask on, Comrade Suzy. Don’t ask questions.


3 posted on 09/05/2025 8:20:25 PM PDT by crusty old prospector
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To: SeekAndFind

3 times a day? Is it effective as an antihistamine? Doesn’t sound like it.


4 posted on 09/05/2025 8:37:02 PM PDT by FamiliarFace (I got my own way of livin' But everything gets done With a southern accent Where I come from. TPetty)
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To: SeekAndFind

Bkmk


5 posted on 09/05/2025 8:56:48 PM PDT by sauropod
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To: SeekAndFind

I used Xlear nasel spray during the pandemic if I had close interaction with other people. I also did Vitamin C&D every day.

Didn’t take the shot. Never got Covid.

https://advancedhealthline.com/is-xlear-nasal-spray-good-for-covid.html


6 posted on 09/05/2025 9:05:25 PM PDT by CaptainK ("No matter how cynical you get, it is impossible to keep up” )
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To: SeekAndFind

unfortunately, everyone will have to inhale three doses per day per nostril every day for the rest of their lives ... how likely is that to happen?


7 posted on 09/05/2025 9:05:27 PM PDT by catnipman ((A Vote For The Lesser Of Two Evils Still Counts As A Vote For Evil))
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To: SuzyQue

My MD told me I didn’t need a vax. Friend’s naturopath recommended Xlear nasal spray to kill covid germs. . We drove all over town to find it, a lot of people looking for it. No shots for us, no Covid.

I have a lifetime supply of Xlear, wonder what else it prevents.


8 posted on 09/05/2025 9:05:55 PM PDT by Veto! (Trump Is Superman)
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To: catnipman

My main concern is how I’m going to get this into my nostrils without removing my mask?


9 posted on 09/05/2025 10:56:18 PM PDT by Right Brother (I don't really care Margaret.)
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To: SeekAndFind

“were less likely to test positive for COVID-19”
.
“Testing positive” is not the same as avoiding COVID-19.


10 posted on 09/05/2025 11:53:25 PM PDT by Does so ("Things will now change in Minneapolis AND AT HOME"....Dem☭¢rat... ∅ one ™ ¿ ¡ ☞ ½¼)
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To: SeekAndFind

“In the United States, azelastine was approved in 2012 to reduce symptoms of seasonal allergies. It is sold as Dymista and is also available generically. Side effects include drowsiness and headache.”

Does it require a prescription?

You would think that anyone with even a cursory interest in journalism would anticipate the most basic questions a reader might have and do a simple Google search to see if the answer is handy. But alas you’d be mistaken. We have to treat all articles as springboards for conducting our own investigations.

It is available over the counter.


11 posted on 09/06/2025 3:13:12 AM PDT by unlearner (I'm tired of being not tired of winning.)
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To: SeekAndFind

Since most of my illnesses seem to start in my sinuses, I’ve taken to using saline spray with a few drops of grapefruit-seed oil (natural antibacterial/antifungal). Very few colds and such since I started - and if something does start up, I use a lavage kit to clan the sinuses out.


12 posted on 09/06/2025 4:25:53 AM PDT by trebb (So many fools - so little time...)
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To: SeekAndFind

This was known years ago.

And was ignored.


13 posted on 09/06/2025 4:30:15 AM PDT by mewzilla (Swing away, Mr. President, swing away! 🇺🇸 🏴󠁧󠁢󠁥󠁮󠁧󠁿)
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To: SeekAndFind
From 2021.

Four years ago.

Azelastine inhibits viropexis of SARS-CoV-2 spike pseudovirus by binding to SARS-CoV-2 entry receptor ACE2

14 posted on 09/06/2025 4:32:20 AM PDT by mewzilla (Swing away, Mr. President, swing away! 🇺🇸 🏴󠁧󠁢󠁥󠁮󠁧󠁿)
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To: SeekAndFind

I found taking nothing is the best solution. Far as I know I’ve never had it nor has the wife. Neither of us take any prescriptions either and we’re 70+


15 posted on 09/06/2025 4:40:46 AM PDT by maddog55 (The only thing systemic in America is the left's hatred of it!)
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To: SeekAndFind; nickcarraway; ransomnote; Jane Long
This is from last month...

Modelling the potential use of pre-exposure prophylaxis to reduce nosocomial SARS-CoV-2 transmission

Nosocomial spread of CoupFlu continues to be an issue.

Isn't that interesting since healthcare workers were made to get the vaxx.

Does that mean that vaxxed healthcare workers continue to a vector for spread if the coof?

Think about that the next time you're thinking about anything elective in a healthcare setting.

16 posted on 09/06/2025 4:47:21 AM PDT by mewzilla (Swing away, Mr. President, swing away! 🇺🇸 🏴󠁧󠁢󠁥󠁮󠁧󠁿)
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To: SeekAndFind

The great Covid scare and hysteria is dead, bury it. Lesson learned? Man’s mRNA jabs killed and disabled.


17 posted on 09/06/2025 5:50:36 AM PDT by delta7
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To: mewzilla

Think about that the next time you’re thinking about anything elective in a healthcare setting.
——————

Think about that the next time you’re thinking about anything which requires you to sign a paper holding them immune from lawsuits. Senile Joe fooled millions.

Never forget, once you inject “ junk” into your body, there is no getting it out.


18 posted on 09/06/2025 5:57:51 AM PDT by delta7
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To: SeekAndFind

Thanks
bfl


19 posted on 09/06/2025 10:20:19 AM PDT by Faith65 (Isaiah 40:31)
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To: SeekAndFind

This was known at the height of the virus


20 posted on 09/08/2025 5:50:05 PM PDT by ballplayer
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