Posted on 09/05/2025 8:05:11 PM PDT by SeekAndFind
A nasal spray typically used to relieve allergy symptoms may help combat COVID-19, according to a new study.
People who received the azelastine nasal spray in a randomized, placebo-controlled trial in Germany were less likely to test positive for COVID-19, researchers reported on Sept. 2.
Only 5 participants administered the spray had laboratory-confirmed COVID-19, compared to 15 in the placebo group, they said.
Spray recipients also had a lower incidence of rhinovirus infections.
The single-center trial involved 450 people receiving the spray or a placebo three times a day for 56 days. The trial lasted from March 2023 to July 2024.
“Azelastine nasal spray could provide an additional easily accessible prophylactic to complement existing protective measures, especially for vulnerable groups, during periods of high infection rates, or before travelling,” Dr. Robert Bals, professor of internal medicine at Saarland University, who led the trial, said in a statement.
In a commentary article, also published by JAMA Internal Medicine, U.S. researchers Dr. Samuel Vidal and Dr. Dan Barouch said that the German scientists reported “promising data.”
Since the trial was carried out at one center and had a relatively modest size, further studies are needed to assess whether the spray is actually effective against COVID-19, Bals and his co-authors said.
“These findings support the potential of azelastine as a safe prophylactic approach warranting confirmation in larger, multicentric trials,” they wrote.
The trial was funded by URSAPHARM Arzneimittel GmbH, which manufactures the spray, and some of the authors are employees of the company.
In the United States, azelastine was approved in 2012 to reduce symptoms of seasonal allergies. It is sold as Dymista and is also available generically. Side effects include drowsiness and headache.
Some earlier papers have also indicated that the spray works against seasonal viruses.
In a trial carried out in India that involved some of the same German researchers, neither arm had COVID-19-related hospitalizations, but recipients of azelastine had lower viral loads and improved symptoms, the researchers said in a 2024 paper.
People who tested positive for COVID-19 and received the antihistamine had lower viral loads than placebo recipients, researchers, including some of the authors of the new paper, said in a 2023 paper. The trial was conducted in Germany.
Both of those trials were funded by URSAPHARM.
Scientists said in 2022 that a study indicated that azelastine reduced the effects of COVID-19 in vitro, or in a laboratory setting. The study received funding from CEBINA GmbH, a partner of URSAPHARM.
Have they developed a definitive test for covid yet?
Jut keep your mask on, Comrade Suzy. Don’t ask questions.
3 times a day? Is it effective as an antihistamine? Doesn’t sound like it.
Bkmk
I used Xlear nasel spray during the pandemic if I had close interaction with other people. I also did Vitamin C&D every day.
Didn’t take the shot. Never got Covid.
https://advancedhealthline.com/is-xlear-nasal-spray-good-for-covid.html
unfortunately, everyone will have to inhale three doses per day per nostril every day for the rest of their lives ... how likely is that to happen?
My MD told me I didn’t need a vax. Friend’s naturopath recommended Xlear nasal spray to kill covid germs. . We drove all over town to find it, a lot of people looking for it. No shots for us, no Covid.
I have a lifetime supply of Xlear, wonder what else it prevents.
My main concern is how I’m going to get this into my nostrils without removing my mask?
“were less likely to test positive for COVID-19”
.
“Testing positive” is not the same as avoiding COVID-19.
“In the United States, azelastine was approved in 2012 to reduce symptoms of seasonal allergies. It is sold as Dymista and is also available generically. Side effects include drowsiness and headache.”
Does it require a prescription?
You would think that anyone with even a cursory interest in journalism would anticipate the most basic questions a reader might have and do a simple Google search to see if the answer is handy. But alas you’d be mistaken. We have to treat all articles as springboards for conducting our own investigations.
It is available over the counter.
Since most of my illnesses seem to start in my sinuses, I’ve taken to using saline spray with a few drops of grapefruit-seed oil (natural antibacterial/antifungal). Very few colds and such since I started - and if something does start up, I use a lavage kit to clan the sinuses out.
This was known years ago.
And was ignored.
Four years ago.
I found taking nothing is the best solution. Far as I know I’ve never had it nor has the wife. Neither of us take any prescriptions either and we’re 70+
Modelling the potential use of pre-exposure prophylaxis to reduce nosocomial SARS-CoV-2 transmission
Nosocomial spread of CoupFlu continues to be an issue.
Isn't that interesting since healthcare workers were made to get the vaxx.
Does that mean that vaxxed healthcare workers continue to a vector for spread if the coof?
Think about that the next time you're thinking about anything elective in a healthcare setting.
The great Covid scare and hysteria is dead, bury it. Lesson learned? Man’s mRNA jabs killed and disabled.
Think about that the next time you’re thinking about anything elective in a healthcare setting.
——————
Think about that the next time you’re thinking about anything which requires you to sign a paper holding them immune from lawsuits. Senile Joe fooled millions.
Never forget, once you inject “ junk” into your body, there is no getting it out.
Thanks
bfl
This was known at the height of the virus
Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.