Does it have a name? Ancient Chinese secret? (In this case Japanese)
Come to think of it, I hadn’t heard about ring around the collar in a long time.....
People who are taking opioids for pain have nothing to do with the "crisis".
People who are taking crap to get high rarely are in physical pain.
Ironically, I’ve learned a LOT from my own health experience and consequent research which I collated into a project I reference as ‘my book’ (I’ll probably never publish it because I have little regard for humanity this decade).
Reinforcing my decision are nearly continuous posts echoing the causes of malaise, pain & disease which fail to highlight the underlying cause: Inflammation.
If I was to rewrite my so-called ‘book’ and expound upon the mere 2 chapters referencing/analyzing the health effects & possible causes/solutions to inflammation I would include the following:
I don’t yet understand the specific mechanism behind why I suddenly began experiencing symptoms of rheumatoid arthritis immediately following my bout with the SARS-COV-2 virus, but I cannot either ignore how easy it would be to become a habitual user of painkillers or how quickly I experience 100% relief (within 30 minutes) after eating a specific preparation of oily fish.
I have a theory about the effects of the spike protein and my own inflammation experience, but I’ve as yet failed to implement what I’ve labeled my ‘detox regimen’.
Your post highlights the latter and I’m going to have to seriously motivate to order some supplies to make that happen. If I’m right, the results should be transformative and I’ll report back here (assuming that yet another vanity post of mine isn’t banished by a rogue mod...).
Does it induce euphoria like opiates?
Tramadol was spoked to be the new “non addictive opioid replacement t” too. That didn’t work out so well, and wasn’t as effective at lain killing as opioid either. Hopeful,y this new drug however will deliver on the promises.
Original research article.
Discovery and development of an oral analgesic targeting the α2B adrenoceptor
Noradrenaline is a major monoaminergic neurotransmitter involved in pain modulation through an α2A-adrenergic receptor. Hence, α2-adrenergic agonists such as clonidine and dexmedetomidine exhibit analgesic and opioid-sparing effects. However, their use is restricted to hospital settings due to potential risks of acute hypertension/hypotension and bradycardia. Here, we report that (Z)-1-(3-ethyl-5-fluorobenzo[d] thiazol-2(3H)-ylidene)propan-2-one [adrenergic inducer of analgesia (ADRIANA)], a newly identified α2B subtype-specific antagonist, specifically promotes noradrenaline release in the murine spinal dorsal horn and produces analgesic effects by stimulating the α2A-dependent pain inhibitory pathway. Orally administered ADRIANA has potent analgesic effects in several nociceptive pain models of mice and nonhuman primates without cardiovascular effects. Mice with genetic loss of the α2B adrenoceptor showed normal responses to mechanical pain, but the analgesic effect of ADRIANA was not significantly detected. These findings reveal that the α2B adrenoceptor is a promising target for nonopioid analgesics through the activation of the α2A-dependent descending pathway.
https://www.pnas.org/doi/10.1073/pnas.2500006122
They always say the new one is “non-addictive.”
Well that ain’t no “fun”.
If you simply prescribe as needed for folks in pain who cares if it has some euphoria
Nearly all opioid deaths are from off market illegal drugs which of course fentanyl is a scourge so poorly measured apparently
You have a pain med script you’re treated like a criminal by cvs or Walgreens
These restrictions with such an aging population have created a bigger problem
Great. Something non+addictive to take with my boos and weed while watching porn. I have been worried about this.
if it actually works as advertised and gets approved by the FDA, it’ll cost only $2,000/day to stay pain-free ...