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Consuming certain sweeteners may increase risk of early puberty
Medical Xpress / The Endocrine Society / ENDO 2025, the Endocrine Society's annual meeting ^ | July 13, 2025 | Yang Ching Chen, M.D., Ph.D. et al

Posted on 07/23/2025 8:38:03 PM PDT by ConservativeMind

Consuming certain sweeteners commonly found in foods and beverages may increase the risk of early puberty in children, particularly among those who are genetically predisposed, according to a study.

The researchers found that consuming aspartame, sucralose, glycyrrhizin and added sugars was significantly associated with a higher risk of early puberty, especially in children with certain genetic traits. The more of these sweeteners the teens consumed, the higher their risk of central precocious puberty.

A type of early puberty known as central precocious puberty is increasingly common. It can lead to emotional distress, shorter adult height, and increased risk of future metabolic and reproductive disorders.

Chen's previous research found that certain sweeteners can directly influence hormones and gut bacteria linked to early puberty. For example, one artificial sweetener called acesulfame potassium or AceK was shown to trigger the release of puberty-related hormones by activating "sweet taste" pathways in brain cells and increasing stress-related molecules. Another sweetener, glycyrrhizin—found in licorice—was found to change the balance of gut bacteria and reduce the activity of genes involved in triggering puberty.

The new findings come from the Taiwan Pubertal Longitudinal Study (TPLS), begun in 2018. The study included data from 1,407 teens. Central precocious puberty was diagnosed in 481 teens. The researchers assessed teens' sweetener intake through validated questionnaires and testing of urine samples. Genetic predisposition was quantified using polygenic risk scores derived from 19 genes related to central precocious puberty. Early puberty was diagnosed based on medical exams, hormone levels and scans.

Sucralose consumption was linked to a higher risk of central precocious puberty in boys and consumption of glycyrrhizin, sucralose and added sugars was associated with a higher risk of central precocious puberty in girls.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS:
Sugar substitutes and black (not red) licorice can both lower the age of puberty.
1 posted on 07/23/2025 8:38:03 PM PDT by ConservativeMind
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To: Mazey; ckilmer; goodnesswins; Jane Long; jy8z; ProtectOurFreedom; matthew fuller; telescope115; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

2 posted on 07/23/2025 8:38:31 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Thanks for the article, I’m trying to delay as long as I can.


3 posted on 07/23/2025 8:48:22 PM PDT by ansel12 ((NATO warrior under Reagan, and RA under Nixon, bemoaning the pro-Russians from Vietnam to Ukraine.))
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To: ansel12

When I was a child, I joined the protests and held the signs “Lower the Age of Puberty”. My classmates and I were pumped about it.


4 posted on 07/23/2025 8:54:26 PM PDT by BipolarBob (I live by trial and error. Mostly error.)
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To: ansel12

I was born too soon.

I’m a wannabe Wilt Chamberlain.


5 posted on 07/23/2025 8:56:56 PM PDT by DIRTYSECRET
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To: BipolarBob

Jerry Lee Lewis was part of that movement I think.


6 posted on 07/23/2025 8:58:15 PM PDT by ansel12 ((NATO warrior under Reagan, and RA under Nixon, bemoaning the pro-Russians from Vietnam to Ukraine.))
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To: ansel12

He certainly did his part. He even helped kinfolk, like cousins and such.


7 posted on 07/23/2025 9:00:54 PM PDT by BipolarBob (I live by trial and error. Mostly error.)
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To: BipolarBob

LOL, down home folk.


8 posted on 07/23/2025 9:06:44 PM PDT by ansel12 ((NATO warrior under Reagan, and RA under Nixon, bemoaning the pro-Russians from Vietnam to Ukraine.))
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To: ConservativeMind

.


9 posted on 07/24/2025 6:01:17 AM PDT by sauropod (Make sure Satan has to climb over a lot of Scripture to get to you. John MacArthur Ne supra crepidam)
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To: ConservativeMind

The 70% of the food consumed by the USA’s children consisting of ultra processed food is having catastrophic results. I suspect that it is not the children of the elite who are consuming so much ultra processed food. Just as they are not going to the terrible public schools in our inner cities, they are likely drinking water and eating healthy food.


10 posted on 07/24/2025 6:40:55 AM PDT by Freee-dame
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