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Short-term high fructose intake can boost bacterial toxin receptors, raising inflammation risk
Medical Xpress / University of Vienna / Redox Biology ^ | June 24, 2025 | Raphaela Staltner et al

Posted on 07/07/2025 10:15:11 PM PDT by ConservativeMind

Despite medical advances, infectious diseases caused by bacteria and viruses are still among the most common causes of death worldwide. What role could fructose play in such diseases?

A research group has now been able to prove for the first time that monocytes, important immune cells in the blood, react more strongly to bacterial toxins after fructose consumption—but not in a positive way. Specifically, the concentration of receptors for certain bacterial toxins increases, making the body more susceptible to inflammation.

In two independent randomized studies with healthy adults, the researchers investigated how the consumption of fructose-sweetened beverages affects the immune response compared to beverages with glucose.

The scientists were able to observe that the intake of fructose, in contrast to the intake of glucose, led to an increase in the concentration of Toll-like receptor 2 in monocytes. Toll-like receptor 2 regulates the immune response, among other things. The higher concentration was accompanied by an increased sensitivity of the monocytes to lipoteichoic acid, a bacterial toxin.

"The concentration of receptors for such toxins in the body increased, which means that the inflammatory response increased," explains study leader Ina Bergheim. Specifically, pro-inflammatory messengers such as interleukin-6, interleukin-1β and tumor necrosis factor-alpha were increasingly released.

"These findings make an important contribution to understanding how individual food components and fructose in particular can influence the immune system," says Bergheim. "They indicate that even short-term, high fructose consumption in healthy people can influence the immune system and increase inflammation."

Future studies should clarify the long-term effects of chronically increased fructose consumption on the immune system and susceptibility to infection, particularly in risk groups with, for example, type II diabetes mellitus or fatty liver disease, which is associated with metabolic dysfunction.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: cornsyrup; diabetes; fructose; inflamation; nutrition
Fructose appears to directly increase inflammation.
1 posted on 07/07/2025 10:15:11 PM PDT by ConservativeMind
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To: Mazey; ckilmer; goodnesswins; Jane Long; jy8z; ProtectOurFreedom; matthew fuller; telescope115; ...

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2 posted on 07/07/2025 10:15:38 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

For diabetics?


3 posted on 07/08/2025 1:48:28 AM PDT by Mark17 (Retired USAF air traffic controller. Father of USAF ISR pilot. Both bitten by the aviation bug)
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To: Mark17

Perhaps. I understand it’s mostly relevant for people who have a fatty liver or are obese. That sugar intake isn’t good for you anyway.


4 posted on 07/08/2025 2:59:06 AM PDT by CandyFloss
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To: ConservativeMind

.


5 posted on 07/08/2025 4:58:49 AM PDT by sauropod (Make sure Satan has to climb over a lot of Scripture to get to you. John MacArthur Ne supra crepidam)
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To: ConservativeMind

bttt


6 posted on 07/08/2025 8:44:46 AM PDT by BenLurkin (The above is not a statement of fact. It is opinion or satire. Or both.)
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To: ConservativeMind

so, fruitarians are gonna die from inflammation ...


7 posted on 07/08/2025 8:52:32 AM PDT by catnipman ((A Vote For The Lesser Of Two Evils Still Counts As A Vote For Evil))
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