Posted on 04/12/2025 9:04:21 PM PDT by SeekAndFind
The purpose of this study was to evaluate the effectiveness of the influenza vaccine during the 2024-2025 respiratory viral season.
Methods
Employees of Cleveland Clinic in employment in Ohio on October 1, 2024, were included. The cumulative incidence of influenza among those in the vaccinated and unvaccinated states was compared over the following 25 weeks. Protection provided by vaccination (analyzed as a time-dependent covariate) was evaluated using Cox proportional hazards regression.
Results
Among 53402 employees, 43857 (82.1%) had received the influenza vaccine by the end of the study. Influenza occurred in 1079 (2.02%) during the study. The cumulative incidence of influenza was similar for the vaccinated and unvaccinated states early, but over the course of the study the cumulative incidence of influenza increased more rapidly among the vaccinated than the unvaccinated. In an analysis adjusted for age, sex, clinical nursing job, and employment location, the risk of influenza was significantly higher for the vaccinated compared to the unvaccinated state (HR, 1.27; 95% C.I., 1.07 – 1.51; P = 0.007), yielding a calculated vaccine effectiveness of −26.9% (95% C.I., −55.0 to −6.6%).
Conclusions
This study found that influenza vaccination of working-aged adults was associated with a higher risk of influenza during the 2024-2025 respiratory viral season, suggesting that the vaccine has not been effective in preventing influenza this season.
Summary
Among 53402 working-aged Cleveland Clinic employees, we were unable to find that the influenza vaccine has been effective in preventing infection during the 2024-2025 respiratory viral season.
Competing Interest StatementThe authors have declared no competing interest.
Funding Statement
This study did not receive any funding
Author Declarations
I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.
Yes
The details of the IRB/oversight body that provided approval or exemption for the research described are given below:
The study was approved by the Cleveland Clinic Institutional Review Board as exempt research (IRB no. 23-625). A waiver of informed consent and waiver of HIPAA authorization were approved to allow the research team access to the required data.
I confirm that all necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived, and that any patient/participant/sample identifiers included were not known to anyone (e.g., hospital staff, patients or participants themselves) outside the research group so cannot be used to identify individuals.
Yes
I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance).
Yes
I have followed all appropriate research reporting guidelines, such as any relevant EQUATOR Network research reporting checklist(s) and other pertinent material, if applicable.
Yes
To the contrary, I heard that people vaccinated with generic flu vaccine (regardless of strain) managed to have some protection, or easier bout with Covid if infected — same goes for “BCG” (tuberculosis one avail in other countries) vaccine and pneumonia shots.
I think it does something to benefit immune system in general for those prone to high risk respiratory ailments. Again, even when the strand is not exact.
And as the aforementioned have more of a track record than Covid vaccines, these findings deserve more worthwhile exploration.
And to add to my above post:
the people who should be getting flu shots are those most prone to get the flu anyway — so even if they DID get the flu, the question is: did the shot (regardless of strain) protect them from the worst blows of the illness?
And lastly, for those people who are extremely weary of mRNA, there should be a vested interest in attesting to the effectiveness of traditional vaccines — because the next goal of BigPharma is to do away with the traditional flu shots, and make those mRNA-based too!
” over the course of the study the cumulative incidence of influenza increased more rapidly among the vaccinated than the unvaccinated.”
Negative efficacy?
My doctor told me that I could take it or leave it. He said The way they manufacture it now Makes it much less effective than the way they used to make it
So you “heard” something. Lol
This study had nothing to do with covid.
I read, it was medical data during the pandemic - I may have even posted some articles on FR back during its height. Kaiser was the source of one, Cedars Sinai Medical Center in Los Angeles another. It was mostly anecdotal but strong statistical correlations were observed in real time in hospitals before the Covid vaccines even came out. Those vaxxed for flu and pneumonia had better survival rates. 💙
And to add:
The posted study says more people vaccinated got the flu - but that’s not the real test about its efficacy.
The real test is whether people most vulnerable to respiratory ailments in the first place (including Covid, but of course flu) SURVIVED the flu or had an easier bout! And I believe that there is much to celebrate about traditional flu shots — as I posted in my 3rd message: the next goal of BigPharma is to replace them with mRNA flu shots. 😱
The problem always is that the flu mutates every year before that year’s vaccine goes into wide usage.
53,000 people work at the Cleveland Clinic???
Wow.
Not surprised about the vax results so much, tho...
From 2021...
Original Antigenic Sin is a Real and Very Serious Reason to Stop Vaccinating Everyone
Only time I've ever been hospitalized for an illness was with complications from the flu. I had indeed gotten the vaxx that year, with plenty of time to acquire immunity. I got a strain they hadn't included and was sicker than I had ever been in my life before or since.
Another useless vaccine..go figure.
This has, for all intents and purposes, already been done. As in, a few years ago now.
Any genetic treatment using the ‘mXXX’ technology is creating spikes that shed into the environment over time. The spikes likely cause the turbo-cancers. They may start from deformed spikes as their creation process ages and breaks down.
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