Free Republic
Browse · Search
General/Chat
Topics · Post Article

Skip to comments.

Exposure to antibiotics as a newborn can impair immune response to vaccines, study finds (Probiotics fix it)
Medical Xpress / Nature ^ | April 4, 2025 | Sanjukta Mondal / David Lynn

Posted on 04/09/2025 9:22:26 PM PDT by ConservativeMind

A recent study found that babies treated with antibiotics within the first few weeks of their life showed weaker immune response to vaccines due to reduced levels of Bifidobacterium—a bacterial species that lives in the human gastrointestinal tract. Replenishing Bifidobacterium in the gut microbiome using probiotic supplements such as Infloran showed promising results in restoring the immune response.

The researchers followed 191 healthy, vaginally born infants from their birth to 15 months: 86% of the participants received the hepatitis B vaccine at birth, and, by six weeks of age, began their routine childhood vaccinations.

The infants were grouped based on their exposure to antibiotics: no direct or maternal exposure, exposed to maternal antibiotics and received at least 48 hours of antibiotic treatment during neonatal care.

The investigation revealed that children who were directly exposed to neonatal antibiotics, not the ones exposed to maternal antibiotics, produced much lower levels of antibodies against multiple polysaccharides included in the 13-valent pneumococcal conjugate vaccine or PCV13 vaccine.

Streptococcus pneumoniae, a bacteria known for causing serious diseases like pneumonia, blood infections, and meningitis, is surrounded by a capsule made up of polysaccharides, or sugar molecules that help the bacteria evade attacks by the body's immune system.

The PCV13 vaccine makes it easier for the immune system to attack S. pneumoniae and produce antibodies by linking the polysaccharide capsule layer to proteins. Exposure to neonatal antibiotics reduces antibody production against such polysaccharides, weakening the immune response.

Experiments on germ-free mice revealed that the lower immune response was linked to a reduced abundance of Bifidobacterium in the gut microbiome. However, giving the mice a mix of Bifidobacterium species or Infloran, a commonly used infant probiotic, helped reverse the negative effects of antibiotics and regain the immune response to PCV13.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: antibiotics; biome
“…giving the mice a mix of Bifidobacterium species or Infloran, a commonly used infant probiotic, helped reverse the negative effects of antibiotics and regain the immune response to PCV13.”
1 posted on 04/09/2025 9:22:26 PM PDT by ConservativeMind
[ Post Reply | Private Reply | View Replies]

To: Mazey; ckilmer; goodnesswins; Jane Long; jy8z; ProtectOurFreedom; matthew fuller; telescope115; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

2 posted on 04/09/2025 9:23:50 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

Do not get your newborn vaccinated.

It greatly increases the probability of the baby getting SIDs or becoming autistic.

After COVID, I have NO TRUST in the medical community, especially BIG PHARMA.


3 posted on 04/09/2025 9:31:26 PM PDT by SoConPubbie (Trump has all the right enemies, DeSantis has all the wrong friends.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

Antibiotics, probiotics… it’s all very confusing. I need to study neutronics.


4 posted on 04/09/2025 9:37:32 PM PDT by monkeyshine (live and let live is dead)
[ Post Reply | Private Reply | To 1 | View Replies]

To: SoConPubbie

And why a hepatitis vax as a new born?


5 posted on 04/09/2025 10:39:06 PM PDT by HollyB
[ Post Reply | Private Reply | To 3 | View Replies]

To: ConservativeMind

Oh, vaccines, and what definition are we using today?


6 posted on 04/10/2025 2:58:33 AM PDT by TalBlack (Their god is government. Prepare for a religious war.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

Read carefully:

This is a treatise on professional idiocy.


7 posted on 04/10/2025 6:05:54 AM PDT by logi_cal869 (-cynicus the "concern troll" a/o 10/03/2018 /!i!! &@$%&*(@ -)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

Breast Feed, at least the first year. Kids turn out tall, good looking, normal, and wonderful. Great teeth too.

Homeschooling may have helped psychologically and spiritually.


8 posted on 04/10/2025 8:04:31 AM PDT by If You Want It Fixed - Fix It
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind
Be miserable but live longer ... What a concept!!!
9 posted on 04/10/2025 10:33:34 AM PDT by Paal Gulli
[ Post Reply | Private Reply | To 1 | View Replies]

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
General/Chat
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson