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Cold plunges enhance cellular stress response in young males, study finds
Medical Xpress / University of Ottawa / Advanced Biology ^ | March 31, 2025 | Bernard Rizk / Kelli E. King et al

Posted on 04/05/2025 10:11:57 AM PDT by ConservativeMind

A new study has unveiled significant findings on the effects of cold water acclimation on autophagic (the cells' recycling system, which promotes cellular health) and apoptotic (the programmed cell death that gets rid of damaged cells) responses in young males.

The research highlights the potential for cold exposure to enhance cellular resilience against stress.

The study involved 10 healthy young males who underwent cold-water immersion at 14°C (57.2°F) for one hour across seven consecutive days. Blood samples were collected to analyze the participants' cellular responses before and after the acclimation period.

"Our findings indicate that repeated cold exposure significantly improves autophagic function, a critical cellular protective mechanism," says Professor Kenny. "This enhancement allows cells to better manage stress and could have important implications for health and longevity."

The research revealed that while autophagy was initially dysfunctional after high-intensity cold stress, consistent exposure over a week led to increased autophagic activity and decreased cellular damage signals.

"By the end of the acclimation, we noted a marked improvement in the participants' cellular cold tolerance," explains King. "This suggests that cold acclimation may help the body effectively cope with extreme environmental conditions."

The implications of this study extend beyond athletic performance. Cold water immersion has gained popularity for its potential health benefits, and this research provides some scientific backing for its efficacy. The findings suggest that proper autophagic activity could not only extend cellular longevity but also prevent the onset of various diseases.

"We were amazed to see how quickly the body adapted," notes King. "Cold exposure might help prevent diseases and potentially even slow down aging at a cellular level. It's like a tune-up for your body's microscopic machinery."

These results apply to young males and more research is needed to see if it would also apply to other cohorts.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: adaptive; cell; stress
Seven days of cold water immersion helped clean up cells via autophagy (self eating).
1 posted on 04/05/2025 10:11:57 AM PDT by ConservativeMind
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To: Mazey; ckilmer; goodnesswins; Jane Long; jy8z; ProtectOurFreedom; matthew fuller; telescope115; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

2 posted on 04/05/2025 10:13:44 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

As long as you don’t mind the significant shrinkage. 😏

You know somebody was gonna say it! 😁


3 posted on 04/05/2025 10:15:30 AM PDT by V_TWIN (America...so great even the people that hate it refuse to leave!)
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To: V_TWIN

What shrinkage. I’ve never had shrinkage.
Are you trying to tell us something about yourself?


4 posted on 04/05/2025 10:16:39 AM PDT by Jonty30 (I can promise I can land any plane that is in the air, because gravity only moves in one direction.)
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To: ConservativeMind

What could have been in the minds of those that came up with the hypothesis ? Next project ,walking on bed of hot coals?


5 posted on 04/05/2025 10:17:27 AM PDT by sopo
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To: ConservativeMind

Get me to that ice bath ASAP!!!


6 posted on 04/05/2025 10:19:35 AM PDT by Jim W N (MAGA by restoring the Gospel of the Grace of Christ (Jude 3) and our Free Constitutional Republic!)
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To: sopo

Next project: Spending the government grant money they got for this on homosexual prostitutes.


7 posted on 04/05/2025 10:21:23 AM PDT by jjotto ( Blessed are You LORD, who crushes enemies and subdues the wicked.)
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To: ConservativeMind

Oh, yeah...

8 posted on 04/05/2025 10:21:39 AM PDT by Jim W N (MAGA by restoring the Gospel of the Grace of Christ (Jude 3) and our Free Constitutional Republic!)
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To: ConservativeMind

Not for me, I don’t want to catch a cold!


9 posted on 04/05/2025 10:24:38 AM PDT by null and void (Americans are a people increasingly separated by our connectivity. H/T MortMan)
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To: V_TWIN
...or to experience significant shrinkage!
10 posted on 04/05/2025 10:26:21 AM PDT by null and void (Americans are a people increasingly separated by our connectivity. H/T MortMan)
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To: ConservativeMind

Humans have spent millions of years acclimating and evolving to handle cold temperatures and this could have led to some type of dependence on periodic exposure to cold for some cellular systems.


11 posted on 04/05/2025 10:34:43 AM PDT by wildcard_redneck ( )
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To: ConservativeMind

IF also causes increased autophagy. Now I wanna know which is better!


12 posted on 04/05/2025 10:35:23 AM PDT by Retrofitted
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To: jjotto

implying some sort of sado-masochism? That aside,I ought to read the article, I assume there may have been some incidental finding in mountain division military training or something like that.


13 posted on 04/05/2025 10:45:18 AM PDT by sopo
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To: Jonty30

Lighten up Francis.....its just a joke. SMH


14 posted on 04/05/2025 10:54:18 AM PDT by V_TWIN (America...so great even the people that hate it refuse to leave!)
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To: V_TWIN

So was mine. :)


15 posted on 04/05/2025 10:56:17 AM PDT by Jonty30 (I can promise I can land any plane that is in the air, because gravity only moves in one direction.)
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To: ConservativeMind

Here in NY....that’s spring...52 is spring...


16 posted on 04/05/2025 11:05:10 AM PDT by Sacajaweau
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To: ConservativeMind

I don’t know any dude stupid enough to do this...


17 posted on 04/05/2025 11:05:51 AM PDT by Sacajaweau
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To: Sacajaweau

I bet you do, but just don’t know he does!


18 posted on 04/05/2025 12:02:40 PM PDT by null and void (Americans are a people increasingly separated by our connectivity. H/T MortMan)
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