Posted on 09/09/2024 8:41:45 PM PDT by ConservativeMind
The American Journal of Gastroenterology has published a new guideline on the treatment of Helicobacter pylori (H. pylori) infection.
H. pylori is a bacterium that infects over half the people in the world, though most are asymptomatic. It can cause dyspepsia, peptic ulcer disease and gastric cancer. This latest clinical practice guideline notes that its prevalence in North America is decreasing, but it still infects 30-40% of the population.
A previous guideline was published in 2017. It had maintained the recommendation of a proton pump inhibitor-clarithromycin triple therapy as the primary treatment option.
In the new guideline, the number one recommendation for treatment-naïve patients is bismuth quadruple therapy. That treatment typically includes a PPI, tetracycline, bismuth and nitroimidazole for 14 days.
"We were already recommending that health care providers move away from PPI triple therapy in 2017 because of increasing problems with chloromycetin resistance among H. pylori strains in the United States," Chey said.
"Despite that recommendation, PPI triple therapy still dominates first-line therapy prescriptions for H. pylori patients in the United States. In this newest iteration of the guideline, we are very clear to say that in essentially all circumstances you should not be prescribing PPI triple therapy, and you should instead be using bismuth quadruple therapy or one of the other suggested treatment options."
The guideline makes 12 total treatment suggestions for patients in a variety of different situations. The number two recommendation for treatment-naïve patients—after bismuth quadruple therapy—is rifabutin triple therapy (a PPI, rifabutin and amoxicillin.) A third option consists of a new, highly potent drug called vonoprazan, combined with the antibiotic amoxicillin, that blocks stomach acid production.
Besides the move away from PPI triple therapy, another change from the 2017 guideline is the discussion of increasingly available molecular testing for antibiotic susceptibility.
(Excerpt) Read more at medicalxpress.com ...
The top therapies are in this paragraph:
“The guideline makes 12 total treatment suggestions for patients in a variety of different situations. The number two recommendation for treatment-naïve patients—after bismuth quadruple therapy—is rifabutin triple therapy (a PPI, rifabutin and amoxicillin.) A third option consists of a new, highly potent drug called vonoprazan, combined with the antibiotic amoxicillin, that blocks stomach acid production.”
Your doctor doesn’t know this, yet, so suggest it by giving them this write up.
“ This latest clinical practice guideline notes that its prevalence in North America is decreasing, but it still infects 30-40% of the population.”
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30-40%? Damn… now my hypochondria is going to get triggered! ;-)
“30-40%? Damn... now my hypochondria is going to get triggered!:-)”
Combine that with dyslexia and you well get better.
There is a sordid history behind what this article proffers as ‘progress’.
A solution is hardly outlined. They just dig a deeper hole and expect desperate patients to jump in.
I had H. Pylori about ten years ago. I had disrhea for years and complained to my doc many times, but he did nothing, I finally did my own research, thought my symptoms matched H.. Pylori, and told doc we should test for it. He said “That’s a good idea.” The test came back positive and he prescribed the common triple therapy at the time that had been developed by an Australian doc. It eradicated it and things got much better.
I was really mad that I had to do my own research and make recommendations to doc.
For decades, people with stomach ulcers were told to adjust their diet and take antacids (IIRC). I know someone who suffered for 25 years before it was recognized that stomach ulcers were caused by H. pylori. Back then I listened to Dr. Gabe Merkin on the radio and he was prescribing antibiotics for stomach ulcers when sufferers came to him as a last resort. They usually got cured. Meanwhile, the medical industry had patients for life insisting that there was no cure.
“I was really mad that I had to do my own research and make reccomendations to doc”
That’s how I found out the covid vaxx was trying to kill me. The doc I was seeing denied it so I switched to a doc that had researched it. And that there is why I am still alive.
Read about Barry Marshall :
Australian physician, Nobel Laureate in Physiology or Medicine, Professor of Clinical Microbiology and Co-Director of the Marshall Centre at the University of Western Australia. Marshall and Robin Warren showed that the bacterium Helicobacter pylori (H. pylori) plays a major role in causing many peptic ulcers, challenging decades of medical doctrine holding that ulcers were caused primarily by stress, spicy foods, and too much acid. This discovery has allowed for a breakthrough in understanding a causative link between Helicobacter pylori infection and stomach cancer.
After Robin Warren discovered colonies of bacteria at gastric ulcer sites, he was contacted by his colleague Barry Marshall, who then successfully cultivated the previously unknown bacteria Helicobacter pylori. Warren and Marshall proved in 1982 that patients could only be cured if the bacteria were eliminated. This is now achieved by treatment with antibiotics, and gastric ulcers are no longer a chronic illness.
Helicobacter pylori
bttt
Doc set up a number of tests for me and said, "It probably isn't H. Pylori but lets test you for that just to be on the safe side."
Called me the next day, "It's H. Pylori. You can pick up your treatment at the pharmacy. Do you still want to do the other tests as well?"
Because I am a big baby I said, "Cancel them all!"
But I do seem to remember that there were four medicines he gave me to take for it.
Afterwards I could drink coffee again.
And there was much rejoicing through out the land.
Your story is similar to mine. I was REALLY steamed that I had to do my own diagnosis and then the doc said “Yeah, good idea, let’s test for H. Pylori.”
Getting bowels back to normal was indeed a reason for rejoicing. I hope no permanent damage was done (me or you) after having that blasted bug for so long. Symptoms come on gradually, so it’s hard to tell how long you had it.
Happy for both of us!
Thank you for this follow up about the relationship between Helicobacter pylori and stomach ulcers and stomach cancer.
Just imagine if there are other cures out there for diseases that are now considered chronic illnesses.
I have one for you. I noticed that I was developing arthritis in one of my hands. By happenstance, I started taking folic acid and after several months I noticed the pain in my hand had gone away. I asked a doctor about the relationship between folic acid and arthritis. His reply was, “Oh, they have known about that for a long time.”
Well, knock me over with a feather! I continue taking a small dose of folic acid every day.
My pleasure.
BTW, that second paragraph is from the Nobel Prize site which Dr. Marshall won for his work.
I never forget to thank God for his Grace and healing, I sometimes forget to mention it.
Don’t forget that He created such geniuses as Dr. Marshall who made such medical breakthroughs to save countless lives and improve quality of life for hundreds of millions.
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