In 1981 Barry Marshall began working with Robin Warren, the Royal Perth Hospital pathologist who, two years earlier, discovered the gut could be overrun by hardy, corkscrew-shaped bacteria called Helicobacter pylori. Biopsying ulcer patients and culturing the organisms in the lab, Marshall traced not just ulcers but also stomach cancer to this gut infection. The cure, he realized, was readily available: antibiotics.
But mainstream gastroenterologists were dismissive, holding on to the old idea that ulcers were caused by stress.
Unable to make his case in studies with lab mice (because H. pylori affects only primates) and prohibited from experimenting on people, Marshall... ran an experiment on ...himself. He took some H. pylori from the gut of an ailing patient, stirred it into a broth, and drank it....Back in the lab, he biopsied his own gut, culturing H. pylori and proving unequivocally that bacteria were the underlying cause of ulcers.
For their work on H. pylori, Marshall and Warren shared a 2005 Nobel Prize. Today the standard of care for an ulcer is treatment with an antibiotic.
Now that is an impressive story.
Brave man to try an experimental medical test on himself.
Thanks for posting.