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Along with lifestyle changes, diabetes is now potentially cured.
1 posted on 07/15/2024 1:03:54 AM PDT by Jonty30
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To: Jonty30
DYRK1A inhibitors for disease therapy: Current status and perspectives

Looks like EGCG from Green Tea is one. Others are listed.

Desmethylbellidifolin (DMB) is a natural xanthone extracted from Gentianella acuta

Gentian supplements are available.

2 posted on 07/15/2024 1:22:32 AM PDT by DannyTN
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To: Jonty30

bkmk


3 posted on 07/15/2024 1:50:01 AM PDT by conserv8
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To: Jonty30

Diabetes is never cured, only delayed. Been diabetic for over 25 years now.....I know. Drugs to rev up my pancreas eventually “burned it out” as my doctor put it. But they are mega-profitable for big pharma, so they keep coming.

It was a happy day in my life when my doctor put me on insulin, letting me stop taking those drugs. Especially metformin, which always left me feeling like I’d ingested an industrial floor cleaner.


5 posted on 07/15/2024 1:55:02 AM PDT by Chad C. Mulligan
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To: Jonty30

Does a diabetic need to increase their insulin production by 700%? Low blood sugar is just as much a problem as high blood sugar.


7 posted on 07/15/2024 2:58:26 AM PDT by jimfr
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To: Jonty30

Sounds promising for type 1 but not so much for type 2.

type 2 is not from a lack of insulin. Producing more without fully knowing how much more can be dangerous as heck, it seems to me.


9 posted on 07/15/2024 3:35:08 AM PDT by Adder (End fascism...defeat all Democrats.)
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To: Jonty30
The therapy involved a combination of two drugs: one is harmine, a natural molecule found in certain plants, which works to inhibit an enzyme called DYRK1A found in beta cells. The second is a GLP1 receptor agonist. The latter is a class of diabetes drug that includes Ozempic, which is gaining attention lately for its side effect of weight loss.

Source: Article liked to by post

What are the risks of taking Ozempic for weight loss? <> The Food and Drug Administration (FDA) approved Wegovy, a brand name for semaglutide, for weight loss in adults who have high cholesterol, type 2 diabetes, or high blood pressure.

Although some people may benefit from taking Ozempic for weight loss if they have a comorbid medical issue, using this prescription medication for the sole purpose of losing weight medicalizes fatness and fails to address the real issue: weight stigma. The so-called “obesity epidemic” harms people living in larger bodies, contributes to anti-fatness and body weight bias, and can lead to mental health problems and eating disorders, such as binge eating disorder, anorexia nervosa, or bulimia nervosa.

Some people with eating disorders or patterns of disordered eating may misuse semaglutide (and other weight loss medications) for weight management since this medication can reduce appetite and caloric intake.2 However, this can be risky, especially for those with anorexia nervosa who may already significantly restrict their food intake—it could increase the likelihood of undernutrition and its many dangerous consequences, such as:5

Reduced muscle functioning
Electrolyte disturbances
Reduced kidney functioning
Chronic gastrointestinal issues
Colon malfunctioning
Increased risk of infection
Depression and anxiety

Source

14 posted on 07/15/2024 4:38:48 AM PDT by Robert DeLong
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To: Jonty30

I haven’t read article yet. Does drug work for Type 1 or Type 2?


20 posted on 07/15/2024 5:57:19 AM PDT by NetAddicted (MAGA2024)
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To: Jonty30

This will help with type 1 diabetes. Type 2 ( insulin resistance ) can be reversed, how? Give up sugar, in all forms. Cut carbohydrates.


25 posted on 07/15/2024 7:36:14 AM PDT by Bullpine
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To: Jonty30

Can this coax new insulin producing cells in a pancreas that has stopped producing insulin for a length of time longer than ten years?

My son is a Type-1 and has been for a decade. Can this treatment potentially bring his Laagerhans cells back to life an cure his Type-1?


28 posted on 07/15/2024 8:03:14 AM PDT by Buckeye Battle Cry (Progressivism is socialism. Venezuela is how it ends.)
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