[Robert DeLong]

The therapy involved a combination of two drugs: one is harmine, a natural molecule found in certain plants, which works to inhibit an enzyme called DYRK1A found in beta cells. The second is a GLP1 receptor agonist. The latter is a class of diabetes drug that includes Ozempic, which is gaining attention lately for its side effect of weight loss.

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What are the risks of taking Ozempic for weight loss? <> The Food and Drug Administration (FDA) approved Wegovy, a brand name for semaglutide, for weight loss in adults who have high cholesterol, type 2 diabetes, or high blood pressure.

Although some people may benefit from taking Ozempic for weight loss if they have a comorbid medical issue, using this prescription medication for the sole purpose of losing weight medicalizes fatness and fails to address the real issue: weight stigma. The so-called “obesity epidemic” harms people living in larger bodies, contributes to anti-fatness and body weight bias, and can lead to mental health problems and eating disorders, such as binge eating disorder, anorexia nervosa, or bulimia nervosa.

Some people with eating disorders or patterns of disordered eating may misuse semaglutide (and other weight loss medications) for weight management since this medication can reduce appetite and caloric intake.2 However, this can be risky, especially for those with anorexia nervosa who may already significantly restrict their food intake—it could increase the likelihood of undernutrition and its many dangerous consequences, such as:5

Reduced muscle functioning
Electrolyte disturbances
Reduced kidney functioning
Chronic gastrointestinal issues
Colon malfunctioning
Increased risk of infection
Depression and anxiety

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[Jonty30]

I always say to take it for 5lb lots and then quit for a few months to let the body catch up and make the requisite lifestyle changes so you don’t have to rely on it.