Posted on 07/08/2024 10:16:37 PM PDT by ConservativeMind
Researchers have found a potential link between putative retinal gliosis and Alzheimer's disease. The study demonstrates that putative retinal gliosis could be a sign of Alzheimer's disease-related neuroinflammation, an inflammatory response within the brain or spinal cord.
Putative retinal gliosis refers to changes in the retina caused by activation of glial cells, which are support cells that become activated when there is damage or disease in the retina. In this study, Edmund Arthur, O.D., Ph.D. found that presumed neuroinflammation was larger in the retina of preclinical Alzheimer's disease patients compared to similarly aged controls, like from postmortem tissues and animal models of Alzheimer's disease.
Preclinical Alzheimer's disease patients are individuals who are cognitively unimpaired but have elevated amyloid beta (Aβ) on positron emission tomography, or PET, imaging.
"Neuroinflammation typically precedes neurodegeneration and clinical symptoms of dementia in Alzheimer's disease," Arthur said. "As an extension of the brain, the retina of the human eye provides a potential non-invasive window for early diagnosis of Alzheimer's disease.
"We quantified presumed neuroinflammation in the retina of preclinical Alzheimer's disease patients using a low-cost and non-invasive technique compared to standard neurodiagnostic methods."
Alzheimer's disease is one of the most common causes of dementia in older adults, accounting for about 60% to 80% of all cases. Pathological changes in Alzheimer's disease typically precede any Alzheimer's disease symptoms by almost two decades.
The progression of Alzheimer's disease, or the Alzheimer's disease continuum, is when pathological changes in the brain that are typically not noticeable to the individual with Alzheimer's disease transition into more noticeable symptoms such as memory problems or disability.
The preclinical phase of Alzheimer's disease is the period in which an individual does not show symptoms but shows biomarker changes that indicate Alzheimer's disease in the brain. The preclinical phase is followed by cognitive impairment.
(Excerpt) Read more at medicalxpress.com ...
Pictures of what your doctor needs to notice are at the link.
bump for reference
Makes sense. If it’s happening in the eye it can be happening in the brain.
Is it a biomarker of dementia if a person’s pupils are always so dilated you can’t figure out the individual’s eye color? Asking for a president.
“Is it a biomarker of dementia if a person’s pupils are always so dilated you can’t figure out the individual’s eye color? Asking for a president.”
Speaking of dilated eyes ... I was watching a true crime story last week where a P.I. solved a crime that the police and FBI couldn’t crack.
He was an expert in body language, and all he needed was to see the video of one of the suspects being questioned. He said that when a person lies, the pupils become very noticeably dilated. That could be the reason Biden’s eyes kept changing throughout the debate.
“ He said that when a person lies, the pupils become very noticeably dilated”
And maybe why Biden often wears those super dark aviator glasses, even when he is not in bright sunshine.
Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.