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Ion channel discovery offers hope for long COVID patients
Medical Xpress / Griffith University / Frontiers in Immunology ^ | May 7, 2024 | Etianne Martini Sasso et al

Posted on 05/16/2024 7:14:32 PM PDT by ConservativeMind

Researchers have made a discovery that could bring relief to those struggling with long COVID.

In a world-first finding, they've identified a way to restore the faulty function of ion channels on immune cells using a well-known drug.

The breakthrough, builds on previous research showing long COVID patients share similar issues with ion channels as those with chronic fatigue syndrome (also known as myalgic encephalomyelitis or ME/CFS).

The team had previously shown success in restoring ion channel function in ME/CFS patients using a drug called Naltrexone, and now they've achieved similar results with long COVID patients.

"Ion channels are integral membrane proteins that facilitate the passage of ions (charged particles) across the cell membrane," Sasso said.

"We found that by restoring the function of these ion channels, important ions such as calcium were again able to move in and out of immune cells, controlling many of the body's biological processes."

This breakthrough offers hope for alleviating various ME/CFS symptoms, including brain fog, muscle fatigue, and issues with the cardiovascular and gastrointestinal systems.

Professor Sonya Marshall-Gradisnik, said the significance of this discovery, achieved through the gold standard test called electrophysiology, will help in better understanding long COVID and ME/CFS paving the way for potential therapies.

The NCNED is preparing to launch two clinical trials, one for long COVID and another for ME/CFS, testing the effectiveness of low-dose Naltrexone.

This drug, typically used for opioid addiction, has shown promising results in restoring ion channel function in previous research and in anecdotal reports from patients.

"We will be undertaking two clinical trials testing the efficacy of low dose naltrexone where the first will be in long COVID patients while the second trial will, for the first time, be in ME/CFS patients," Professor Marshall-Gradisnik said.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: covaxsideeffects; covid1984; ionchannel; longcovid
Generic naltrexone can be found for under $30.

Imagine how crazy it sounds to think a drug only meant for treating drug abuse can also help Long COVID-19 sufferers get better.

1 posted on 05/16/2024 7:14:32 PM PDT by ConservativeMind
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To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

2 posted on 05/16/2024 7:15:06 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

I’m anxious and game.


3 posted on 05/16/2024 7:15:53 PM PDT by drSteve78 ( Older Je suis Deplorable. Even more so)
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To: ConservativeMind

Just what your body needs....more drugs.


4 posted on 05/16/2024 7:19:29 PM PDT by Sacajaweau
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To: ConservativeMind

Is there any hope for Long TDS victims?


5 posted on 05/16/2024 7:25:36 PM PDT by Paladin2
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To: ConservativeMind

Ivermectin works very well.


6 posted on 05/16/2024 7:34:06 PM PDT by Tom Tetroxide
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To: Paladin2
>>hope for Long TDS victims?

It may be terminal.

They drank the kool-aid.

7 posted on 05/16/2024 7:44:37 PM PDT by Deaf Smith (When a Texan takes his chances, chances will be taken that's for sure.)
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To: ConservativeMind

1.5 or 3.0 mg/day here, but not specifically for long Covid. Full disclosure: this is why I was interested in dietary fiber on another thread (side effect).


8 posted on 05/16/2024 7:51:47 PM PDT by steve86 (Numquam accusatus, numquam ad curiam ibit, numquam ad carcerem™)
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To: ConservativeMind

LOL, no I don’t take it for drug abuse either; they take more like 50-100mg if taking naltrexone (instead of more common naloxone).


9 posted on 05/16/2024 8:00:44 PM PDT by steve86 (Numquam accusatus, numquam ad curiam ibit, numquam ad carcerem™)
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To: Tom Tetroxide

As the article points out, CFS and long Covid patients have certain biochemical abnormalities in common; treating these is well outside the scope of ivermectin even if ivermectin gives other benefits.


10 posted on 05/16/2024 8:03:07 PM PDT by steve86 (Numquam accusatus, numquam ad curiam ibit, numquam ad carcerem™)
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To: ConservativeMind

Anyone interested can visit Truth Social, find Florida Sharkman and see what he has to say, as well as the testimonials.

There is no shortage of information now on ways to reverse these issues.


11 posted on 05/16/2024 8:09:39 PM PDT by 1st I.D Vet
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To: ConservativeMind

I read a while ago that scientists had determined Long Covid does not exist. Hope this drug doesn’t hurt even a minority of patients. I was one of the 0.5% hurt by a med once.


12 posted on 05/16/2024 8:11:21 PM PDT by NetAddicted (MAGA2024)
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To: Tom Tetroxide

“Ivermectin works very well.”

Starting taking Ivermectin when I was exposed and tested positive.

My friends who were exposed when I was were in bed for 5 days....I sneezed 5 times.

Yep. Ivermectin worked BIG TIME!!!


13 posted on 05/16/2024 8:20:35 PM PDT by lizma2
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To: lizma2

The thread has nothing to do with acute Covid.


14 posted on 05/16/2024 8:24:48 PM PDT by steve86 (Numquam accusatus, numquam ad curiam ibit, numquam ad carcerem™)
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To: ConservativeMind
First they made up “covid.”

Then they made up “long covid.”

15 posted on 05/16/2024 8:51:54 PM PDT by HIDEK6 (God bless Donald Trump)
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To: ConservativeMind
First they made up “covid.”

Then they made up “long covid.”

16 posted on 05/16/2024 8:53:26 PM PDT by HIDEK6 (God bless Donald Trump)
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To: lizma2

You can buy Ivermectin here.
https://www.ivermectin.com/


17 posted on 05/18/2024 7:28:46 AM PDT by Tom Tetroxide
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To: steve86

Vitamin C, vitamin D, and zinc with copper does wonders for supercharging one’s immune system.


18 posted on 05/18/2024 7:29:42 AM PDT by Tom Tetroxide
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To: steve86

Do you know what COVID is? COronaVIrus Disease.

What does the coronavirus cause? The common cold (two versions), bronchitis, and pneumonia.

It’s amazing how the common cold can have so much fear instilled about it.


19 posted on 05/18/2024 7:31:41 AM PDT by Tom Tetroxide
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