Posted on 03/30/2024 2:13:58 PM PDT by ShadowAce
People who have taken at least three doses of the original version of the COVID-19 mRNA vaccine have been strongly immune imprinted, a study by the University of Washington (UW) found.
Consequently, when vaccinated with the most recent COVID-19 XBB.1.5 mRNA boosters, recipients produced few to no antibodies specific to the XBB.1.5 variant.
Immune imprinting occurs when previous infections or vaccinations leave such a strong immune memory that the body continues to produce immune cells and antibodies targeting the previous immune experience—even when exposed to a new variant or vaccine.
“[Immune imprinting] could be a problem if the person was unable to mount a useful immune response against a new variant,” Dr. Stanley Perlman, an immunologist and microbiologist at the University of Iowa, told The Epoch Times. He was not involved in the study.
Immune imprinting is a well-recognized phenomenon that can occur with other infections and viruses.
New influenza infections distinct from previous variants can overcome imprinting from influenza vaccinations and infections.
However, in the UW study, immune imprinting persisted even among those infected with new omicron variants.
“It is completely different from what we know from the influenza virus,” said Mr. Veesler.
“Immune imprinting persists after multiple exposures to Omicron spikes through vaccination and infection, including post XBB.1.5 booster vaccination, which will need to be considered to guide future vaccination,” the authors wrote.
More than 20 people with a history of three or more Wuhan-variant mRNA vaccines participated in the study. Most had been infected with pre- and post-omicron COVID-19 infections.
In addition to the original mRNA vaccines, most participants took the bivalent booster or the XBB.1.5 booster. By the time of the study, all participants had taken four to seven shots.
The authors found that most of the antibodies produced after XBB.1.5 mRNA inoculation were best at neutralizing the original Wuhan COVID-19 variant.
The antibodies had the second-greatest neutralizing potency against the BA.2.86 omicron variant. The antibodies were third most potent against XBB.1.5 in people who took the XBB.1.5 vaccine.
These antibodies were cross-reactive, meaning they could also bind to other variants, including the XBB.1.5 variants.
However, there were few to no antibodies specific to XBB.1.5.
Some people did produce new immune cells that recognized only XBB.1.5. However, of the 12 participants evaluated, only five had immune cells that recognized XBB.1.5 but not the Wuhan variant.
One hypothesis is that residents of Seattle, where most of the samples came from, were exposed to the virus so many times—mainly through vaccination but also infection—that they developed antibodies and immune memory cells preferable to the original virus.
“People in Seattle, including myself, have been so compliant,” Mr. Veesler said. “We have been exposed many, many times over the past four years through vaccination and usually at least one infection. And that’s very unusual to have so many exposures in such a short amount of time—up to seven vaccine doses in the cohort we analyzed.”
“Inactivated vaccines induce a weaker immune response, so there is less opportunity for the response to be biased [toward one variant],” Dr. Perlman said.
“mRNA vaccines may have been so good and elicited such strong immune responses that the imprinting may be stronger than what we have been used to seeing with vaccines for other viruses such as for influenza virus,” Mr. Veesler said.
So the COVID-19 vaccine protects you from the COVID-19 booster?
imprinting. old news to most here. very bad from a future health standpoint.
All of this should have been known before the first jab was ever given.
As we can see, the studies are going on now because they used the people as guinea pigs.
This disgusts me.
10 more boosters and you are SUPERHUMAN.
Yes, it is.
I thought it worth posting just because it's starting to hit media now. Maybe the word will get out to even more (read "mainstream") outlets.
So good in fact that these multiple mRNA jabbed people caught the virus multiple times. Talking with 4 friends yesterday while hanging out, the only one who was jabbed ( he got 2 jabs) has had 4 or 5 covid episodes (assuming that the test he was given is even accurate. Which I doubt since what he described are common allergy symptoms). Those of us un Jabbed never had covid or had one mild episode.
I’ve never had a covid shot and as far as I know, never had covid. I mean, maybe I did, but I’ve never been ill enough to bother checking. I quit my job back in the day because I refused to get vaccinated. Sometimes I feel like I am on another planet or the twilight zone.
So the COVID-19 vaccine protects you from the COVID-19 booster?
It may have or is still doing that.
Thanks for posting this.
Some of us don’t have computer brains enabling us to recall everything ever thought of let alone visiting our planet re viruses.
[Sometimes I feel like I am on another planet or the twilight zone.]
You (WE) ARE in The Twilight Zone.
There were dramatic effects on a few people surrounding me, I’m sorry to say.
That being said, COVID-19(84) was an excellent dry run for the coming Mark of the Beast.
Whether this rehearsal was on purpose I do not know - but it seems rather obvious the “pandemic” was on purpose.
YMMV
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