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Hydroxychloroquine Use During COVID Pandemic May Have Induced 17,000 Deaths, New Study Finds
Euronews ^ | 06/01/2024 | Oceane Duboust

Posted on 01/07/2024 1:23:13 PM PST by nickcarraway

The drug hydroxychloroquine was prescribed off-label during the pandemic and touted in particular by a prominent French researcher.

The antimalarial drug hydroxychloroquine may have induced nearly 17,000 deaths in six countries during the first wave of the COVID-19 pandemic.

This molecule was presented during the pandemic as a miracle cure by a minority of health professionals, among them the French microbiologist Didier Raoult.

The scientist’s belief that the drug was a cure for COVID-19 was soon echoed by some policymakers. French President Emmanuel Macron notably visited his facility and US President Donald Trump recommended the drug in 2020, stating that he had already taken it.

Avoiding COVID was about more than just keeping 2 metres apart, study finds The use of the drug sparked controversy as many health specialists noted the lack of research or scientific evidence of its effectiveness against COVID-19.

The US Food and Drug Administration (FDA) issued an emergency use authorisation of hydroxychloroquine (HCQ) in March 2020 but revoked it in June.

The drug was found in particular to cause severe side effects such as heart rhythm abnormalities.

Nearly 17,000 deaths induced by hydroxychloroquine A new study published in Biomedicine & Pharmacotherapy now estimates the fallout from the drug’s off-label use.

Researchers led by Jean-Christophe Lega, a Professor of Therapeutics in the Lyon, France hospital system, investigated studies conducted in France, the United States, Belgium, Italy, Spain, and Turkey from March 2020 until July 2020.

"HCQ use was associated with an 11 per cent increase in the mortality rate in a meta-analysis of randomised trials," the study noted, citing a meta-analysis published in 2021 in Nature which the researchers used to calculate the number of deaths induced by the drug.

'It’s not gone. It’s changing. It’s killing': The COVID variants the WHO is watching closely The estimated number of deaths in European countries was roughly 240 in Belgium, 199 in France, 1,822 in Italy, and 1,895 in Spain.

"What we need to bear in mind is that this is a rough estimate, in the sense that it only concerns a few countries over a short period, and that the total number of deaths is probably much higher," Lega told French broadcaster France 3.

The results should be taken with caution as it is a statistical analysis. One limitation of the study was that in France, Turkey, and Belgium, in particular, data concerning exposure to the drug was scarce.

Yet the researchers say: "This result argues in favour of tightly regulating access to off-label prescriptions during future pandemics".


TOPICS:
KEYWORDS: chinavirus; covid; covid1984; deathdrug; fakenews; followdirections; hcq; hydroxychloroquine; hyped; jeanchristophelega; mortality
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To: gitmo

What was their reasoning for stop giving her a prescription that she had already been getting?


121 posted on 01/07/2024 3:34:08 PM PST by nickcarraway
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To: DugwayDuke

You can’t show that it saved millions of lives independent of Fauci and Big Pharma, who profited handsomely from a lab created virus.

It saved nobody and may have cost the lives of millions.


122 posted on 01/07/2024 3:35:17 PM PST by Jonty30 (In a nuclear holocaust, there is always a point in time where the meat is cooked to perfection. )
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To: nickcarraway

They said it was being used to treat COVID.


123 posted on 01/07/2024 3:37:21 PM PST by gitmo (If your theology doesn't match your biography, what good is it?)
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To: Jim Noble

Yeah. I uh, know someone who is in the medical field. It’s still in the protocol at the hospital where they work. Still destroying people’s kidneys too, but try telling Fauci or the bean counters at Corporate Catholic Health Care that.

Oops.


124 posted on 01/07/2024 3:38:14 PM PST by OKSooner ("You won't like what comes after America." - Leonard Cohen.)
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To: KittyKares
That’s terrible. They knew she was taking it for what the medical profession considered a valid reason. Incidents like that — and many others during the lockdown — make me so mad.

The lockdown on Ivermectin was another oppressive reaction. It is sold OTC around the world and is one of the safest drugs on the market.

125 posted on 01/07/2024 3:38:59 PM PST by gitmo (If your theology doesn't match your biography, what good is it?)
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To: cpdiii

“I do not believe this article. HCQ has been administered literally billions of times in the tropics for prevention of malaria. If this study were true we would have had millions of deaths in the tropics and a valid study on this would have been published. I took the drug when I worked in Nigeria. They are gaslighting us.”

It only kills in the presence of a flue virus. /sarc


126 posted on 01/07/2024 3:39:19 PM PST by Moltke (Reasoning with a liberal is like watering a rock in the hope to grow a building.)
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To: nickcarraway

gaslighting


127 posted on 01/07/2024 3:39:34 PM PST by one guy in new jersey
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To: week 71

week 71 wrote: “
Begin Quote @ 85 No dug - the doctors you trust blatantly lied to your face.
1. If you take the ‘vaccines’ you won’t get covid or transmit it.
2. Naturally immunity is ineffective against covid and you must get the jab.
3. Kids with a 99.97% chance of surviving covid still need the covid vaccines.
4. Walking around with a dust mask will also protect against virus.
I could go on. It’s laughable the people you trust.
End Quote.

No, the ‘doctors’ you trusted blatantly lied to your face.
Here’s a few.
1. Take supplements, you won’t get covid or transmit it.
2. Naturally immunity is better than the vaccines against against covid and you don’t need the vaccines.
3. Kids don’t get covid and don’t need the covid vaccines (even though thousands of kids died from covid.)
4. Ivermectin will cure covid.
“I could go on. It’s laughable the people you trust.”


128 posted on 01/07/2024 3:40:29 PM PST by DugwayDuke (Most pick the expert who says the things they agree with.)
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To: Jonty30

Jonty30 wrote: “You can’t show that it saved millions of lives independent of Fauci and Big Pharma, who profited handsomely from a lab created virus. It saved nobody and may have cost the lives of millions.”

The vaccines did save millions of lives as evidenced by the reduction in deaths once the vaccines were available.
There is no reputable source that supports your claim that vaccines cost millions of lives.


129 posted on 01/07/2024 3:43:14 PM PST by DugwayDuke (Most pick the expert who says the things they agree with.)
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“The use of the drug sparked controversy as many health specialists noted the lack of research or scientific evidence of its effectiveness against COVID-19.”

I wonder what the position of these specialists was regarding the rushed-in vaccine.


130 posted on 01/07/2024 3:43:49 PM PST by Moltke (Reasoning with a liberal is like watering a rock in the hope to grow a building.)
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To: Steve Van Doorn

“i can’t find any information showing this. That seems backward from how it functions. I doubt this part.”

So after looking at the Flockhart table..that many Doctors and researchers use...you might want to rethink what you are saying.

And btw, there are MANY studies that have looked quercetin as an inhibitor of P450 AND P-glycoprotein.


131 posted on 01/07/2024 3:44:03 PM PST by RummyChick
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To: DugwayDuke

Pretty juvenile response. The inertia of your vaccine religion is heading down the wrong direction and you know it.


132 posted on 01/07/2024 3:44:46 PM PST by week 71
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To: nickcarraway

LOL!


133 posted on 01/07/2024 3:44:50 PM PST by kiryandil (Rocco is roccking again!!)
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To: LadyDoc
Two more recently published (matched-control) studies (2023), one from Brazil, one from Belgium. The study from Brazil does not find any positive effect of HCQ whereas the Belgian study finds a reduction in mortality risk by 57%.

However, concerning the point made in the article that initiated this thread none of the studies found an increased mortality in Covid-19 patients given HCQ!

Real-Life Data on Hydroxychloroquine or Chloroquine with or Without Azithromycin in COVID-19 Patients: A Retrospective Analysis in Brazil

Efficacy and safety of in-hospital treatment of Covid-19 infection with low-dose hydroxychloroquine and azithromycin in hospitalized patients: A retrospective controlled cohort study

134 posted on 01/07/2024 3:46:58 PM PST by ScaniaBoy (Part of the Right Wing Research & Attack Machine)
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To: RummyChick

If anyone really wants to look at Quercetin you can look at the pharmacology at the Drug Bank.

https://go.drugbank.com/drugs/DB04216


135 posted on 01/07/2024 3:52:02 PM PST by RummyChick
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To: RummyChick
checked. Quercetin is weak inhibitors according to the list of P450 2E1 and 1A2
HCQ a weak inhibitor for P450 2D6.
To be clear cytochrome P450 superfamily of enzymes. They do act as a minor inhibitor.
Though for a short term use this is not a concern i would have.
https://drug-interactions.medicine.iu.edu/MainTable.aspx?_gl=1*1kpf5je*_ga*MTY4MTAyNTI5MC4xNzA0NjcwNzYy*_ga_61CH0D2DQW*MTcwNDY3MDc2Mi4xLjAuMTcwNDY3MDc2Mi42MC4wLjA.
136 posted on 01/07/2024 3:52:31 PM PST by Steve Van Doorn
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To: dforest

👍


137 posted on 01/07/2024 3:53:42 PM PST by laplata (They want each crisis to take the greatest toll possible.)
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To: lastchance

What evil bastards they are.


138 posted on 01/07/2024 3:54:21 PM PST by laplata (They want each crisis to take the greatest toll possible.)
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To: Mark
“a prominent French researcher.” How much in his bank account NOW?

No, you are wrong! Professor Raoult did not make any money on HCQ. Actually that is probably one of the problems with this drug. The patent has lapsed and it is too cheap to make big profits.

Professeur Raoult and co-workers probably saved hundreds of lives in the region of Marseille in south-eastern France using HCQ+AZ (and later on Zn) in early Covid-19.

139 posted on 01/07/2024 3:56:33 PM PST by ScaniaBoy (Part of the Right Wing Research & Attack Machine)
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To: JimRed
"-- among those to whom it was administered too late to help. It's been used for many decades to treat malaria without killing people."
Hydroxychloroquine with zinc is effective in preventing the replication of the Covid-19 virus during the initial replication stage. If administered after the initial replication stage, it is much less effective.
140 posted on 01/07/2024 4:00:06 PM PST by Hiddigeigei ("Talk sensesa to a fool and he calls you foolish," said Dionysus - Euripides)
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