Posted on 12/19/2023 1:03:14 PM PST by ConservativeMind
Atopic dermatitis (AD) is a chronic inflammatory skin disease whose main symptoms are redness, swelling, and itchy rashes. It is more common in people with a genetic predisposition. The manifestation of symptoms depends on interactions among the immune system, environmental factors, and gut microbiota.
Knowing how these factors correlate is fundamental to a better understanding of the disease and serves as a basis for novel therapies, according to a review.
Also known as atopic eczema, AD affects 7%-10% of adults and 20%-25% of young children.
A hypothesis that has been proposed to explain the significant increase in developing countries is the lack of exposure to beneficial bacteria, which may affect immune maturation (the process by which the immune system develops a response after first contact with microorganisms).
The authors of the review show that gut microbiota is at the center of the most recent research. "Besides being responsible for 70% of immune system regularization, for maintaining skin barrier integrity and the structure of the gastrointestinal tract, and for controlling nutrient absorption and energy balance, the gut microbiome is directly connected to the skin via what's known as the gut-skin axis," said Sabri Saeed Sanabani.
The article features recent evidence that alterations to gut microbiome composition can contribute to the pathogenesis of AD. Studies have reported an increased abundance of Clostridium difficile, Escherichia coli, and Staphylococcus aureus, as well as a decreased abundance of bacteria that produce short-chain fatty acid (SCFAs), such as Bifidobacteria and Bacteroides, in the gut microbiome of AD patients compared to healthy controls.
A reduction in levels of SCFAs is often associated with intestinal inflammation in otherwise healthy subjects.
(Excerpt) Read more at medicalxpress.com ...
It would seem feeding these, if already present, or supplementing with a probiotic, as well, would address the lack of SCFA.
The fiber and probiotics also helps reduce the pathogenic bacteria listed above.
But I'm a spry 65 in all other ways, though - so as afflictions go, this ain't so bad.
My food issues are so bad that I can’t even do probiotics. I react to even small amounts of those.
Prebiotics are out as well. High histamine levels.
I know what I need to do to change things, just cannot do enough to make it happen.
It’s a bit more complicated than that.
All this demonstrates is the ongoing idiocy of the medical research establishment as they bounce around in their dark labs scrambling for the next billion-dollar pill.
You desperately need counsel of a naturopath to guide you through healing your gut.
Immediately, before disease removes any chance of recovery.
I’ve seen one.
I am also praying and asking for that Red Sea sized miracle.
That is in the works.
It’s been recently, not like I’ve done it and it didn’t work.
Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.