Posted on 10/16/2023 9:09:00 PM PDT by ConservativeMind
For men with Peyronie's disease (PD), nonsurgical treatment including injections of collagenase clostridium histolyticum (CCH) produces high satisfaction with sexual outcomes—with fewer adverse events compared to surgery.
Peyronie's disease is a condition in which the penis becomes curved due to scar-like tissue called plaque, resulting from an abnormal healing response after injury.
Surgery has long been the standard treatment for PD. In 2014, the US FDA approved CCH as a nonsurgical alternative. Treatment includes injections of CCH, with the aim of breaking down the plaque tissue causing the penile curvature.
Forty men with PD were randomly assigned to CCH injection therapy or surgery. Nonsurgical treatment included CCH injections, followed by the use of a traction device (RestoreX) to help stretch and shape the penis plus the oral medication sildenafil. Most patients underwent multiple courses of CCH treatment.
Men assigned to surgical treatment underwent appropriate surgery to reduce their penile curvature, followed by use of RestoreX traction plus sildenafil.
After three months, 50% of men assigned to CCH reported being "very satisfied" with their outcomes, compared to 21% in the surgery group. Men in the CCH group also reported better erectile function: 100% versus 68%. However, scores on a standard erectile function score were similar between groups.
Men undergoing surgery had greater improvement in penile curvature: 65 degrees, compared to 32.5 degrees in the CCH group. Penile length increased by an average of one centimeter with CCH injections, compared to a one-half centimeter reduction with surgery.
Orgasmic function was better in men assigned to CCH; most other subjective outcomes were similar between groups. Adverse event rates were higher in the surgery group: four times higher overall than with CCH.
Although surgery produces greater improvement in penile curvature, sexual function and overall patient satisfaction appear higher with CCH injection therapy.
(Excerpt) Read more at medicalxpress.com ...
Paula Jones-make her a proven liar?
Bill wasn’t crooked until he stuck it in crooked Hillary
I guess that length adjustable splint idea never did become a common, accepable treatment for this condition. //
Some good news - the impeached *Bubba will continue to date.
I look forward to watching TV with my granddaughter when those commercials come on.
NOT !!!
“It will all dissipate under the weight of its own inadmissibility” — Hillary Clinton
Slick’s crookedness cost him $300,000.
“ despite a bit less perfection in the outcome.”
Well, don’t get bent out of shape over it.
There once was a fellow from Kent...
Hate those crooked carrot ads...
Heh!
;-)
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