Posted on 09/02/2023 8:27:05 PM PDT by ConservativeMind
A new dementia risk score, which draws on 11 mostly modifiable risk factors, identifies people at risk—from midlife onward—of developing the disease within the next 14 years, suggests a large long term study.
The UK Biobank Dementia Risk Score, or UKBDRS for short, outperformed three other widely used risk scores originally developed in Australia (ANU-ADRI), Finland (CAIDE), and the U.K. (DRS), the findings show.
In all, 220,762 (average age just under 60) people from the UK Biobank study and 2,934 (average age 57) from the Whitehall II study were included in the final analysis.
The researchers compiled a list of 28 established factors associated with a heightened or reduced risk of developing dementia, to which they applied a statistical method (LASSO regression) designed to identify and discard the least relevant factors, and so focus the score on the strongest predictors.
This produced 11 predictive factors for any type of dementia—the UK Biobank Dementia Risk Score (UKBDRS).
The 11 factors were: age; education; history of diabetes; history of/ current depression; history of stroke; parental dementia; economic disadvantage (Townsend deprivation index) high blood pressure; high cholesterol; living alone; and male sex.
Within 14 years, 3,813 (nearly 2%) and 93 (just over 3%) participants developed dementia in the UK Biobank and Whitehall II groups, respectively.
UKBDRS-APOE produced the highest predictive score, closely followed by the UKBDRS, and then age alone, followed by DRS, CAIDE, and finally ANU-ADRI.
Referring to the illustrative example provided, she explains, "While older age (60 and above) and APOE confer the greatest risk, modifiable factors, such as diabetes, depression, and high blood pressure also have a key role. For example, the estimated risk for a person with all of these will be approximately three times higher than that of a person of the same age who doesn't have any."
(Excerpt) Read more at medicalxpress.com ...
“The 11 factors were: age; education; history of diabetes; history of/ current depression; history of stroke; parental dementia; economic disadvantage (Townsend deprivation index) high blood pressure; high cholesterol; living alone; and male sex.”
A lot of these are modifiable, even starting today.
I’d rather be happily oblivious during the Great Reset.
Obviously not causative factors. Clickbait.
No study could ever come close to replicating even a single one of those other than a statistical link a/k/a a casual relationship. time to start drinking one or more but less than three glasses of red wine per week to prevent heart disease.
Education and economic disadvantage are actually proxies for brain size. People with large brains have more brain cells to lose before they turn into Demonrat voters.
“Education and economic disadvantage are actually proxies for brain size. People with large brains have more brain cells to lose”
That’s completely and totally false.
We’re they all taking statins?
I think that was a ‘lite’ joke.
Consuming too many carbohydrates, especially seeds and seed oils are bad. Getting too many omega 6 PUFAs are bad. One suspects that these will push someone toward dimentia.
What?
No soy for me! To what type of seeds are you referring?
Great question. I believe statins do way more harm than good.
That's why I always tamp little plugs into my ears at night.
Don't want to lose any brain cells, and start voting Dem!
Regards,
You will be among the first lined up against the wall.
Just wow. I sincerely hope I missed the sarcasm tag.
Otherwise, we're doomed
I’ll take the line up.
I wasnt’ really joking on that point, just because of how bad I think it will be. They intend to kill billions. I wouldn’t want to be a survivor in that world.
I've always avoided "male sex."
Regards,
Damn, could’ve gave this test to Biden when he was VP in 2009 and saved us a lot of headaches
I know that I haven’t met everybody in the world with dementia or Alzheimer’s, but the ones I have met seem to have one thing in common. Bad attitude / pessimistic outlook in life / mean steak.
I know it’s not true across the board, but just my own experience.
What is male sex mean? Males? Males having sex with males? Males sexually active?
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