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Prior hookworm infection could offer protection from severe COVID-19 symptoms
Medical Xpress / Malaghan Institute of Medical Research / Science Immunology ^ | Aug. 14, 2023 | Oyebola O. Oyesola et al

Posted on 08/15/2023 7:03:28 PM PDT by ConservativeMind

Prior infection by a parasitic hookworm has been shown to protect mice from severe SARS-CoV-2 disease, offering a potential explanation as to why certain human populations seemed to fare better during the height of the COVID-19 pandemic.

The study looked at hookworm infection in the lungs of mice, as their immune system and cell biology closely mirrors our own. The collaboration found that the mice infected with hookworm were less likely to develop severe COVID symptoms and recovered from the infection much more quickly than their counterparts, even after the worms were cleared from the body.

Looking more closely at what was going on at a cellular level, the study observed that the hookworms were affecting a transformational change to specific type of lung-resident immune cells called macrophages.

"Post-helminth infection we could see a stark difference at the transcriptomic level—the level at which different genes are switched on or off—between macrophages that have been exposed to helminth infection and those that haven't," says Dr. Hilligan.

The result was that these helminth-affected macrophages were much better at raising the alarm to other infectious threats—in this case the COVID-19 virus. They did this by secreting specific chemical compounds that recruit other immune cells called CD8 T-cells, which specialized in removing viruses, to the site of the infection much faster than the control group.

"We found the recruitment for these CD8 T-cells, which are essential for viral responses, were boosted. Thanks to these modified macrophages, the T-cells came into infected tissue faster and cleared infection faster, which resulted in much less severe disease symptoms.

"What's more, this effect seems to be long-lasting, with the macrophages retaining this very strong ability to recruit and activate CD8 T-cells long after the hookworm has been cleared from the body."

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: covid; hookworm
Hookworms can be your friends.
1 posted on 08/15/2023 7:03:28 PM PDT by ConservativeMind
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To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

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2 posted on 08/15/2023 7:03:56 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

We’re the mice treated with any deworming medication? Or did the researchers tell them “you’re a mouse, not a horse”?


3 posted on 08/15/2023 7:07:18 PM PDT by KarlInOhio (Democrats' version of MAGA: Making America the Gulag Archipelago )
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To: ConservativeMind

Maybe they dosed them with Ivermectin to get rid of the worms...


4 posted on 08/15/2023 7:07:51 PM PDT by Bobalu (I'm homesick for a country that no longer exists...)
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To: KarlInOhio

“Y’all” don’t forget “Y’all”...


5 posted on 08/15/2023 7:12:22 PM PDT by EEGator
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To: ConservativeMind

May be I have hookworms? I had covid symptoms, tested positive, but covid left my body in 42 short hours.


6 posted on 08/15/2023 7:14:49 PM PDT by entropy12 (Career politicians like DeSantis build wealth. Trump sacrificed his wealth to serve people.)
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To: ConservativeMind

I kept reading that as Bookworm.

And was thinking Bookworms, like Amish don’t watch TV


7 posted on 08/15/2023 8:12:44 PM PDT by algore
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To: ConservativeMind

I think in India and Africa ivermectin may be given, or other parasite remover medication’s could be given to the patient for hookworms.A lot of thinking is that covet is really a parasite or parasite removing medication’s are miracle drugs for Covid.


8 posted on 08/15/2023 8:32:28 PM PDT by tinamina (Remember when Biden said “we have developed the most sophisticated voting fraud system ever”? )
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To: ConservativeMind

You can meet lots of worms in D.C.


9 posted on 08/15/2023 8:47:55 PM PDT by ransomnote (IN GOD WE TRUST)
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To: ConservativeMind

I believe this is most likely more ‘cover’ to explain away why countries that skipped the Covid ‘vaccine’ fared better, and those which had HCQ or Ivermectin fared better, those without lockdowns fared better. It’s embarrassing to the medical regime so they’re looking for excuses....


10 posted on 08/15/2023 8:49:41 PM PDT by ransomnote (IN GOD WE TRUST)
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To: ConservativeMind

So there is truth to the old saying about a cut or scrape, “rub some dirt in it”.


11 posted on 08/15/2023 10:36:19 PM PDT by ETCM (“There is no security, no safety, in the appeasement of evil.” — Ronald Reagan)
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To: ETCM

Ivermectin kills COVID-19 & the Hookworm. They should pass it out like anti-radiation pills.


12 posted on 08/16/2023 3:24:48 AM PDT by spincaster
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To: ConservativeMind

Guess what the treatment for hookworm is...


13 posted on 08/16/2023 3:30:53 AM PDT by mewzilla (We will never restore the republic if we don't first secure the ballot box.)
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To: mewzilla
From the CDC (https://www.cdc.gov/parasites/zoonotichookworm/health_professionals/index.html):
14 posted on 08/16/2023 6:18:52 AM PDT by Ronaldus Magnus
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To: ConservativeMind

Just when Arkies got used to wearing shoes to prevent hookworm!

Hookworm lifestyle...The barefoot boy with cheeks of tan steps into dog poo. The extremely small hookworms hook into his foot, eat into his bloodstream and travel to the lungs. There they cause coughing and the hookworm is spat into the throat and into the intestines where they hook into the intestine lining and begin to feed. Severe loss of weight occurs. Then the eggs are pooped out waiting for someone else to step in the poop.

You kill them by taking an emetic, then a weak insect poison to kill the worms. Then poop in a proper commode or outhouse.

Then thirty days later you take a a second treatment and are free from hookworms. Start wearing shoes.


15 posted on 08/16/2023 6:41:21 AM PDT by Ruy Dias de Bivar (“No man’s life, liberty, or property are safe while the legislature is in session.”)
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To: Ruy Dias de Bivar

I forgot to mention, over 100 years ago a popular weight loss medication was a pill containing....hookworms.


16 posted on 08/16/2023 6:43:54 AM PDT by Ruy Dias de Bivar (“No man’s life, liberty, or property are safe while the legislature is in session.”)
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To: ransomnote

I’ve gotta get my eyes checked . . . at first, I thought it said “bookworm”, not “hookworm”. Heh.


17 posted on 08/16/2023 10:39:45 AM PDT by AFB-XYZ (Stand up, or bend over)
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