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Dissolution of Spike Protein by Nattokinase Holy Grail of COVID-19 Vaccine Detoxification
PETER A. MCCULLOUGH ^ | FEB 21, 2023 | PETER A. MCCULLOUGH, MD, MPH™

Posted on 05/31/2023 7:28:50 AM PDT by dennisw

By Peter A. McCullough, MD, MPH

Far and away the most common question I get from those who took one of the COVID-19 vaccines is: “how do I get this out of my body.” The mRNA and adenoviral DNA products were rolled out with no idea on how or when the body would ever breakdown the genetic code. The synthetic mRNA carried on lipid nanoparticles appears to be resistant to breakdown by human ribonucleases by design so the product would be long-lasting and produce the protein product of interest for a considerable time period. This would be an advantage for a normal human protein being replaced in a rare genetic deficiency state (e.g. alpha galactosidase in Fabry’s disease). However, it is a big problem when the protein is the pathogenic SARS-CoV-2 Spike. The adenoviral DNA (Janssen) should broken down by deoxyribonuclease, however this has not be exhaustively studied.

This leaves dissolution of Spike protein as a therapeutic goal for the vaccine injured. With the respiratory infection, Spike is processed and activated by cellular proteases including transmembrane serine protein 2 (TMPRSS2), cathepsin, and furin. With vaccination, these systems may be avoided by systemic administration and production of Spike protein within cells. As a result, the pathogenesis of vaccine injury syndromes is believed to be driven by accumulation of Spike protein in cells, tissues, and organs.

Nattokinase is an enzyme is produced by fermenting soybeans with bacteria Bacillus subtilis var. natto and has been available as an oral supplement. It degrades fibrinogen, factor VII, cytokines, and factor VIII and has been studied for its cardiovascular benefits. Out of all the available therapies I have used in my practice and among all the proposed detoxification agents, I believe nattokinase and related peptides hold the greatest promise for patients at this time.

Tanikawa et al examined the effect of nattokinase on the Spike protein of SARS-CoV-2. In the first experiment they demonstrated that Spike was degraded in a time and dose dependent manner in a cell lysate preparation that could be analogous to a vaccine recipient. The second experiment demonstrated that nattokinase degraded the Spike protein in SARS-CoV-2 infected cells. This reproduced a similar study done by Oba and colleagues in 2021.

Nattokinase is dosed in fibrinolytic units (FU) per gram and can vary according to purity. Kurosawa and colleagues have shown in humans that after a single oral dose of 2000 FU D-dimer concentrations at 6, and 8 hours, and blood fibrin/fibrinogen degradation products at 4 hours after administration elevated significantly (p < 0.05, respectively). Thus an empiric starting dose could be 2000 FU twice a day. Full pharmacokinetic and pharmacodynamic studies have not been completed, but several years of market use as an over-the-counter supplement suggests nattokinase is safe with the main caveat being excessive bleeding and cautions with concurrent antiplatelet and anticoagulant drugs.

Based on these findings, nattokinase and similar products such as serrapeptase should undergo well-funded, accelerated preclinical and clinical development programs. The issue at hand is the urgency of time, similar to that with SARS-CoV-2 infection and empiric early therapy. It will take up to 20 years to have a fully developed pharmaceutical profile to characterize the safety and efficacy of nattokinase in the treatment of vaccine injury and post-COVID syndromes. Large number of people are sick now and many believe empiric treatment is justified given sufficiently low risk of side effects and potentially high reward. My recommendation is to discuss this with your doctor or seek a specialist in holistic or naturopathic medicine who is experienced with the safety profile of nattokinase in a range of applications.


TOPICS: Health/Medicine
KEYWORDS: covid; covidvaccine
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1 posted on 05/31/2023 7:28:50 AM PDT by dennisw
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To: dennisw

This might also explain why the Japanese are among the most vaccinated, and not experiencing the “died suddenly” syndrome anywhere near the level of other countries—they eat natto.


2 posted on 05/31/2023 7:31:41 AM PDT by chajin ("There is no other name under heaven given among people by which we must be saved." Acts 4:12)
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To: dennisw

Amazon Nattokinaese
https://www.amazon.com/s?k=Nattokinase&i=hpc&ref=nb_sb_noss

If I had gotten vaxxed I would take this nattokinase plus loads of D3. Ivermectin. 10 grams sodium ascorbate (form of vitamin C) daily. Taken in 5 divided doses.


3 posted on 05/31/2023 7:32:19 AM PDT by dennisw (Never attribute to stupidity, that which is adequately explained by malice)
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To: dennisw

My recommendation is to discuss this with your doctor or seek a specialist in holistic or naturopathic medicine who is experienced with the safety profile of nattokinase in a range of applications.”

It’s astounding to see an exceptionally renowned cardiologist make this recommendation. But kudos to the great Dr. McCullough for being humble enough to seek input outside of his profession to solve this problem.

The knowledge system that is medicine in the west is completely broken.


4 posted on 05/31/2023 7:32:26 AM PDT by ConservativeDude
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To: chajin

Ever eat natto? I like it!


5 posted on 05/31/2023 7:32:54 AM PDT by dennisw (Never attribute to stupidity, that which is adequately explained by malice)
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To: dennisw

It’s very good!


6 posted on 05/31/2023 7:35:13 AM PDT by DariusBane (Liberty and Risk. Flip sides of the same coin. So how much risk will YOU accept? Vive Deo et Vives)
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To: dennisw

Bromelain is another effective fibrinolytic enzyme that can deactivate the spike protein.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999995/


7 posted on 05/31/2023 7:36:29 AM PDT by jimwatx
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To: dennisw

I’ve been taking it for years.


8 posted on 05/31/2023 7:43:03 AM PDT by struggle
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To: chajin

I have read that an extended fast (3-7 days) helps eliminate the lipid nano-particles.

As I recall, it has something to do with how, during fast-induced ketosis, the body is aggressively looking for the most easily available fats/proteins in the blood first, making those a likely target.


9 posted on 05/31/2023 7:46:36 AM PDT by PGR88
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To: struggle

Me too. I’m trying to get them to switch my mom to a combo Natto plus aspirin to replace Plavix, but they’re still giving us the “3 more months” story every time we go in. At the beginning, they told us she would be on it “only 6 months,” and here it is a year later.


10 posted on 05/31/2023 7:56:26 AM PDT by ponygirl (An Appeal to Heaven)
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To: dennisw
--- "fermenting soybeans"

Waiting tor the FDA to tweet, "You're not a natto. Cone on, y'all."

11 posted on 05/31/2023 7:56:47 AM PDT by Worldtraveler once upon a time (Degrow government)
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To: dennisw

I saw in the comments that statement that CDC Director Rochelle Wàllensky was never legally sworn in.

There’s an apparent “epidemic” of missing swearing in.

Austin, Blinken, Mayorkas and others!

That pattern tells me that they don’t want to be held accountable to have protected the Constitution from enemies foreign and domestic. They’re traitors, it appears to me.


12 posted on 05/31/2023 8:00:28 AM PDT by rx
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To: dennisw

Speaking of Dr. McCullough, I haven’t seen the Branch Covidians here to attack him lately.


13 posted on 05/31/2023 8:04:23 AM PDT by wjcsux (On 3/14/1883 Karl Marx gave humanity his best gift, he died. )
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To: ponygirl

I’m trying to get them to switch my mom to a combo Natto plus aspirin to replace Plavix...


Yes, I understand this situation. I would love to eat natto but take effient (same class drug). And maybe like your mom, scared to go against the doc’s recommendations. IIRC, natto also helps keep that arteries clean, hence the reason why the antiplatets...had a Stent put in my heart artery last December.

I had my first Stent installed 8 years ago. First it was 3 months them 6, then a year. Finally, ready to get off Plavix and the cardiologist upped it to another year. I quit on my own at that point. But I didn’t know about the protective effects of natto then.


14 posted on 05/31/2023 8:27:11 AM PDT by Deepeasttx ( Sensitivity/diversity training, along with DEI are all un-walled reeducation camps....for now.)
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Don’t worry. Bill Gates is ensuring the vax is injected into the world food supply so everybody can be forced to benefit


15 posted on 05/31/2023 8:28:15 AM PDT by dsrtsage ( Complexity is just simple lacking imagination)
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To: dennisw; neverdem; ProtectOurFreedom; Mother Abigail; EBH; vetvetdoug; Smokin' Joe; Global2010; ...
I'll just leave this here...
Bring Out Your Dead

Post to me or FReep mail to be on/off the Bring Out Your Dead ping list.

The purpose of the “Bring Out Your Dead” ping list (formerly the “Ebola” ping list) is very early warning of emerging pandemics, as such it has a high false positive rate.

The false positive rate was 100%.

At some point we may well have a high mortality pandemic, and likely as not the “Bring Out Your Dead” threads will miss the beginning entirely.

*sigh* Such is life, and death...

Quarantine the sick. Protect the vulnerable. Hang the guilty. Free everyone else.

16 posted on 05/31/2023 8:43:26 AM PDT by null and void (Men Are from Mars, Women Are from Venus, Wookies Are From Kashyyyk)
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To: ConservativeDude

Just love Dr. Peter McCullough! A godly man and doctor who rose above the one world govt. evil and stood firm on his knowledge.

Saved thousands with budesone and Ivermectin!


17 posted on 05/31/2023 8:50:20 AM PDT by YouGoTexasGirl ( )
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To: chajin

“...the Japanese are...not experiencing the “died suddenly” syndrome anywhere near the level of other countries”

That’s an interesting observation. I certainly have not heard of any Japanese athlete “dying suddenly.” I wonder if there is data to support that.


18 posted on 05/31/2023 8:54:45 AM PDT by ProtectOurFreedom (I don’t like to think before I say something...I want to be just as surprised as everyone else.)
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To: ponygirl

Going on two years +, I still have blood clots from a single J&J clot shot.


19 posted on 05/31/2023 9:00:35 AM PDT by Cold Heart
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To: chajin

Thanks


20 posted on 05/31/2023 9:02:15 AM PDT by Cold Heart
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