Posted on 05/20/2023 9:14:29 AM PDT by ConservativeMind
Soil-transmitted helminth infections are caused by different species of parasitic worms, including whipworms, hookworms and roundworms. Worldwide, more than 1.5 billion people are infected with at least one soil-transmitted helminth, with most of the infected population living in low- and middle-income countries.
Infected people can experience symptoms like stomach pain, diarrhea and anemia, while heavy infections can lead to malnutrition, impaired growth and physical development. In severe cases, it can even cause blockages in the intestine that may require surgery.
To treat soil-transmitted helminth infections, safe drugs are available but the efficacy varies widely. The current treatments recommended by the World Health Organization (WHO) are albendazole and mebendazole. However, in the case of the whipworm Trichuris trichiura, a single dose of these drugs can only cure 17% of the infected people as shown in this study.
To fill the anthelminthic drug pipeline, Swiss TPH researchers have now tested the drug emodepside for the first time in humans infected with soil-transmitted helminths in a phase IIa study.
"In this study, Emodepside showed high cure rates for all three soil-transmitted helminths," said Emmanuel Mrimi, Ph.D. candidate. The lowest dose tested, 5 mg of emodepside, cured 83% of people infected with whipworm. "An increase of emodepside to 15 mg resulted in complete cure of all people. Curing people infected with whipworm has never been achieved with the current anthelminthic treatments." In addition, high efficacy was also observed against roundworm and hookworm.
"The drug has also other important characteristics. It is well tolerated and most adverse events in the trial were mild," said Mrimi.
Emodepside is an anthelminthic treatment used to date in veterinary medicine. "Drug repurposing is a key strategy in research for anthelminthic drug discovery and development that is neglected and underfunded," said Jennifer Keiser, "most repurposed drugs come from veterinary medicine."
(Excerpt) Read more at medicalxpress.com ...
It had only mild effects on tested humans, while increasing the cure rate from 17% to 100%, for whipworm.
Wait -— that’s an ANIMAL drug!!! Shriek!!! People can’t use that!!! Like Ivermectin for Covid!!! That’s DANGEROUS!!! Quick -— someone call Fauci!!!
I take garlic every day. Garlic is safe for humans and (in much smaller doses) for animals. Garlic has a lot of health benefits but something it has been used for since ancient times is fighting parasitic infestations.
I got Mr K (not the one on this forum) to start taking garlic every day. He was going bald and after a short time his hair started growing back. You can’t even tell where the bald spot used to be. Some of the hair is growing back its original color.
Whatever happened to Ivermectin, or is it too much cheaper than this Emodepside to suit the drug industry?
My 6 year old brother had pinworm 70 years ago. Any idea what he was treated with? At this ping list I have seen anecdotal reports from people who have taken Ivermectin and ended up feeling much better than they have for years. Any studies on whether they might have had undiagnosed parasites? Do we have figures on the percent of US people with some kind of parasite?
Obligatory: “THEY’RE TELLING PEOPLE TO TAKE HORSE DEWORMER!” comment.
Here's the Brand name at Petco.
Wonder if they tryed a medicine that won the Nobel prize in human medicine that works great on parasites especially of the worm variety.
Ivermectin is a great drug. Nobel prize was well deserved.
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