What really killed COVID-19 patients: It wasn't a cytokine storm, suggests study (Secondary bacterial pneumonia from ventilators)

Medical Xpress / Northwestern University / Journal of Clinical Investigation ^ | May 4, 2023 | Catherine A. Gao et al

[ConservativeMind]

Secondary bacterial infection of the lung (pneumonia) was extremely common in patients with COVID-19, affecting almost half the patients who required support from mechanical ventilation. By applying machine learning to medical record data, scientists found that secondary bacterial pneumonia that does not resolve was a key driver of death in patients with COVID-19. It may even exceed death rates from the viral infection itself.

The scientists also found evidence that COVID-19 does not cause a "cytokine storm," so often believed to cause death.

"Our study highlights the importance of preventing, looking for and aggressively treating secondary bacterial pneumonia in critically ill patients with severe pneumonia, including those with COVID-19," said senior author Dr. Benjamin Singer.

The investigators found nearly half of patients with COVID-19 develop a secondary ventilator-associated bacterial pneumonia.

"Those who were cured of their secondary pneumonia were likely to live, while those whose pneumonia did not resolve were more likely to die," Singer said. "Our data suggested that the mortality related to the virus itself is relatively low, but other things that happen during the ICU stay, like secondary bacterial pneumonia, offset that."

The study findings also negate the cytokine storm theory, said Singer.

"The term 'cytokine storm' means an overwhelming inflammation that drives organ failure in your lungs, your kidneys, your brain and other organs," Singer said. "If that were true, if cytokine storm were underlying the long length of stay we see in patients with COVID-19, we would expect to see frequent transitions to states that are characterized by multi-organ failure. That's not what we saw."

The study analyzed 585 patients in the intensive care unit (ICU) at Northwestern Memorial Hospital with severe pneumonia and respiratory failure, 190 of whom had COVID-19.

[Political Junkie Too]

You're still not commenting on the studies that were presented in the videos that show the effectiveness of HCQ/Quercetin+zinc in reducing SARS.

Is it your position that you are discrediting these published studies?

-PJ

[gas_dr]

I responded on point — these are in vitro studies. They are not in vivo studies. What happens on a dish is often not what happens in the body. While the studies may be correct in an isolated controlled in vitro study, there significant data including article which demonstrate that HCQ is not effective against Covid 19.

So I am not discrediting the study. It might be accurate. But the environment — in vitro as opposed to in vivo can be different and this is consistent with observation. I have now commented twice on the study. Hopefully this clarifies my thoughts.

[Political Junkie Too]

Yes, you clarified your points. A little extra effort went a long way.

Thanks.

-PJ

[bagster]

Jesus doesn’t like it when you lie. And lie you have with intent and malice. For shame.

I will be pursuing legal remedies on behalf of my client, World traveler once upon a time for libel and slander and any damn thing else I can think of.

My Law Offices of Dewie, Cheatum, and F'off will be in contact with you.

[bagster]

I will pray for your enlightenment as well as your soul.

The balls on you.

[mewzilla]

With a FWIW, just ran across on Twitter...

Rebel Ro
@45RebelRo

We had never used these ventilator settings in my 17 yrs as a RN that NIH/CDC insisted on to remove hospital liability- My God ppl would have a PEEP of 22 or 24-blowing out the lungs and damaging the heart-oh and then the Remdisivir
1:45 PM · May 13, 2023