Posted on 04/04/2023 7:01:39 PM PDT by ConservativeMind
Cold activates a cellular cleansing mechanism that breaks down harmful protein aggregations responsible for various diseases associated with aging. A research team has now unlocked one responsible mechanism.
Professor Dr. David Vilchez used a non-vertebrate model organism, the nematode Caenorhabditis elegans, and cultivated human cells. Both carried the genes for two neurodegenerative diseases that typically occur in old age: amyotrophic lateral sclerosis (ALS) and Huntington's disease. Both diseases are characterized by accumulations of harmful and damaging protein deposits—so-called pathological protein aggregations. In both model organisms, cold actively removed the protein clumps, thus preventing the protein aggregation that is pathological in both ALS and Huntington's disease.
A key finding was that the proteasome activity can also be increased by genetic overexpression of the activator. That way, disease-causing proteins can be eliminated even at the normal body temperature of 37 degrees Celsius.
It has long been known that while extremely low temperatures can be harmful to organisms, a moderate reduction in body temperature can have very positive effects. For example, a lower body temperature prolongs the longevity of cold-blooded animals like worms, flies or fish.
Even in humans, a correlation between body temperature and lifespan has been reported. Normal human body temperature is between 36.5 and 37 degrees Celsius. While an acute drop in body temperature below 35 degrees leads to hypothermia, human body temperature fluctuates slightly during the day and even reaches a cool 36 degrees during sleep. Interestingly, a previous study reported that human body temperature has steadily declined by 0.03 degrees Celsius per decade since the Industrial Revolution, suggesting a possible link to the progressive increase in human life expectancy over the last 160 years.
(Excerpt) Read more at medicalxpress.com ...
YES!!
So glad I decided to live in South Dakota!
LOVE THE COLD!
I’m 77 and being cold doesn’t help my cause at all....
It’ll be about 10 degrees when I get up tomorrow. Windy and a light snow. About 20 degrees at the moment.
Now men can tell their wive the reason they keep the bedroom window open during winter: it’s science!
Never mind that millions of people have retired to a tropical climate and aging people with asthma and arthritis find relief in warmer dry climates, thats just a coincidence.
Rhoda Morganstern said it. She said she moved to Minneapolis from the Bronx because she figured she’d keep better.
If this were true life expectancies in new jersey or new york would be longer than in florida. They aren’t.
Its a certain kind of cold. One that isnt too cold that kills you or helps you to get sick. Also factor in shorter days and lower vitamin d production in cold weather periods.
Being down in florida prevents killing cold, or cold that helps you get sick. The kind of cold you want there is refreshing cold, the kind that feels good after being in the warmth and sun, making vitamin d. Air conditioning cold.
On hot humid days, I like to just sit around and drink.
There goes my plan to retire to the Mid-South from Detroit.😉
Um...no.
For any number of reasons.
I keep the window open at night for a different reason.
Think beans...
Yet, at the same time folks like Gates and the WEF want to cull the population.
You honestly cannot make this up.
All cold does is shrink size of male organ.
It seemed to be of limited value to those poor souls on the Titanic.
Donner party . . .
Hmmmm ... guess I should stop setting my heated mattress pad to “high” before I settle in at night during the cold weather days ...
Nope ... I sleep better and deeper when I’m comfy & warm — But I do have a low-level fan on too ... so maybe it balances out ???
Oh ... and the “surf sounds” on Hubby’s white-noise machine helps too — LOL... how did we ever do without all this ??
Another thing Climate Catastrophe causes!!
Is that why Russian babushkas are so hot?
Seems the Russian winters change them very quickly from attractive babes to lumps of lard and wrinkles.
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