Posted on 03/09/2023 8:23:06 PM PST by ConservativeMind
A new study brings precision to the understanding of which antibiotics work best for acne treatment and why. This is important for two key reasons. Acne affects nearly everyone at some point in life—it is, in fact, the eighth most common disease for all humans, affecting more than 85% of adolescents and young adults. And second, because antibiotics have long been an important go-to treatment for acne, dermatologists write more antibiotic prescriptions than any other specialty in medicine.
Broad-spectrum antibiotics do not distinguish between good and bad bacteria, so they try to inhibit them all. In contrast, narrow-spectrum antibiotics target specific pathogens, giving beneficial bacteria a chance to survive.
About three quarters of prescriptions dermatologists write are for tetracycline-class antibiotics. A new Yale study examined sarecycline, a third-generation tetracycline derivative with a narrow-spectrum activity, which targets Cutibacterium acnes, the bacterium most doctors believe is behind acne and promotes skin inflammation.
…But in 2018, the FDA approved a new antibiotic called sarecycline for the treatment of moderate-to-severe acne vulgaris. Unlike its predecessors, this new drug has specificity for C. acnes and other clinically-relevant Gram-positive bacteria.
…Their model revealed a surprising finding. Unlike other antibiotics, sarecycline is bound to not one, but two active sites on the ribosome.
…Their discoveries are groundbreaking. This is the first group to visualize the structure of the C. acnes ribosome itself and make several intriguing observations. They learned that the ribosomes have proteins with zinc-free and zinc-bound isoforms. Some dermatology research suggests that zinc supplementation might help treat acne vulgaris and help antibiotic treatments work better. This work further supports that zinc supplementation may be helpful in treating acne.
(Excerpt) Read more at medicalxpress.com ...
Groundbreaking, in most cases: Personal hygiene, washing your hands and gently washing your face at least 3 times per day, plus your hair at least once per week (plus any day that you built up a sweat), plus changing your pillow cover at least 2x (or more) per week, will frustrate the environment for acne.
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Taking antibiotics for a long time is harmful because the intestine and bacteria convert fiber to biotin, pentathonic acid, lipoic acid, paba.
Accutane is retinoic acid. Retinoic acid reduces the parathyroid hormone. The body wants to be able to have a good level of parathyroid hormone, so it tries to reduce retinoic acid from the blood. To reduce it, it uses vitamin c, k, and pregnenolone, so one might have a low level of these.
Point of fact:
A single application of antibiotics without follow up to address the effects is significant enough to majorly impact long term health.
Doctors haven’t a clue.
Really. So if you have a massive infection you don’t think antibiotics are useful?
Got it. Clear on how you think and what you know
I was checking out FR on Rosacea and they said Selsun Blue helped, wonder if it would work on acne.
This is back in 2012 and 2013
https://freerepublic.com/focus/f-chat/3073121/posts
https://freerepublic.com/focus/f-chat/2924710/posts
So, you either didn’t see my other comment...or chose to ignore it.
Got it. /s
I think those two posts are so diametrically opposed to each other that I didn’t realize they were composed by the same person
So which do you believe?
Or am I missing your overall point?
Confirmation bias:
More addictive than fentanyl.
Now that’s just plain funny
And hence the rationale for my 4th book.
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