Posted on 02/13/2023 1:40:03 PM PST by ConservativeMind
Eating too much salt is not only bad for our blood pressure and cardiovascular system—it could also adversely impact the immune system.
A team is reporting that salt can disrupt key immune regulators called regulatory T cells by impairing their energy metabolism. The findings may provide new avenues for exploring the development of autoimmune and cardiovascular diseases.
A few years ago, research revealed that too much salt in our diet can negatively affect the metabolism and energy balance in certain types of innate immune cells called monocytes and macrophages and stop them from working properly.
The researchers further showed that salt triggers malfunctions in the mitochondria, the power plants of our cells.
Regulatory T cells, also known as Tregs, are an essential part of the adaptive immune system. They are responsible for maintaining the balance between normal function and unwanted excessive inflammation.
Scientists believe that the deregulation of Tregs is linked to the development of autoimmune diseases like multiple sclerosis. Recent research has identified problems in mitochondrial function of Tregs from patients with autoimmunity.
Previous research has also shown that excess salt could impact Treg function by inducing an autoimmune-like phenotype. In other words, too much salt makes the Treg cells look like those involved in autoimmune conditions.
The new study has now discovered that sodium disrupts Treg function by altering cellular metabolism through interference with mitochondrial energy generation. This mitochondrial problem seems to be the initial step in how salt modifies Treg function, leading to changes in gene expression that showed similarities to those of dysfunctional Tregs in autoimmune conditions.
Even a short-term disruption of mitochondrial function had long-lasting consequences for the fitness and immune-regulating capacity of Tregs in various experimental models.
(Excerpt) Read more at medicalxpress.com ...
If you have autoimmune issues, reducing salt may be beneficial for these cells.
Gotta be false or I’d have died years ago 🤣🤣🤣
Answer: use potassium chloride salt (no sodium)
Whole lotta salt makes good Virginia hams!
Salt is a silent killer. Even the “normal” amount is much too high.
That's the truth!
https://smile.amazon.com/gp/product/B01GBAJR9C
What if everything you know about salt is wrong? A leading cardiovascular research scientist explains how this vital crystal got a negative reputation, and shows how to lower blood pressure and experience weight loss using salt. The Salt Fix is essential reading for everyone on the keto diet!
We’ve all heard the recommendation: eat no more than a teaspoon of salt a day for a healthy heart. Health-conscious Americans have hewn to the conventional wisdom that your salt shaker can put you on the fast track to a heart attack, and have suffered through bland but “heart-healthy” dinners as a result.
What if the low-salt dogma is wrong?
Dr. James DiNicolantonio has reviewed more than five hundred publications to unravel the impact of salt on blood pressure and heart disease. He’s reached a startling conclusion: The vast majority of us don’t need to watch our salt intake. In fact, for most of us, more salt would be advantageous to our nutrition—especially for those of us on the keto diet, as keto depletes this important mineral from our bodies. The Salt Fix tells the remarkable story of how salt became unfairly demonized—a never-before-told drama of competing egos and interests—and took the fall for another white crystal: sugar.
According to The Salt Fix, too little salt can:
• Make you crave sugar and refined carbs
• Send the body into semistarvation mode
• Lead to weight gain, insulin resistance, type 2 diabetes, cardiovascular disease, chronic kidney disease, and increased blood pressure and heart rate
But eating the salt you desire can improve everything, from your sleep, energy, and mental focus to your fitness, fertility, and sexual performance. It can even stave off common chronic illnesses, including heart disease.
The Salt Fix shows the best ways to add salt back into your diet, offering his transformative five-step program for recalibrating your salt thermostat to achieve your unique, ideal salt intake. Science has moved on from the low-salt dogma, and so should you—your life may depend on it.
I thought aldosterone controlled sodium levels, varying by intake…
(Low sodium intake then really high intake is worse than a stable moderate intake…)
An aside, the number of interactions and interplay between everything in the human system is so complex as to seem pretty impossible, to me, to be able to nail down “this or that” interactions.
I find the more I know, the more I realize I don’t know.
Answer: use potassium chloride salt (no sodium)
~~~~~
Maybe if you want to get on a law enforcement watch list.
So...I coulda got over COVID in four days instead of the five it took me?
Still, they can have my salt shaker when they pry it from my cold, dead, desiccated hands.
It is interesting you bring this up, because I actually had to add salt to my diet, after getting chronically dehydrated.
Studies do show an optimum intake appears to be from 2,800 mg of sodium a day to over 6,000 mg, but I also know many people already have compromised bodies and actually can’t afford the higher blood pressure their bodies will produce with that amount of sodium.
I will look into that book. Thanks!
(Couldn’t resist)
Study finds that salt cuts off the excess grants to while coated people.
“Gotta be false or I’d have died years ago”
You and me, both. I salt potato chips sometimes.
I think this is a real thing, I know this by observing my own health. Looking at some frozen food and thinking that there’s no salt in it, they’re actually loaded with Salt Solutions and you don’t need to add any salt to get an excessive sodium load. For example, frozen salmon has 17% of your daily recommended sodium, just put pepper on it with lemon juice and you’ll still end up having a massive dose of sodium.
.
I developed HBP a few years ago. The medication I was on didn’t work, as my BP would fall extremely low after being way too high. The cardiologist asked me if I watch my salt intake, and I told him I didn’t but I’m not one to eat or add salt to food as I don’t like the taste. ( exception is potatoes which I rarely eat) So he put me on a diuretic and I have fewer BP problems that I know of, I don’t check it all the time.
It’s probably not the amount of salt itself but rather the proportion in relation to other electrolytes such as potassium. Deficiency in one exacerbates problems with the other.
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