Posted on 01/09/2023 6:56:56 PM PST by semimojo
Background: During Late 2022, the SARS-CoV-2 Omicron BA.5 sublineages accounted for most of the sequenced viral genomes worldwide. Bivalent mRNA vaccines contain an ancestral SARS-CoV-2 strain component plus an updated component of the Omicron BA.4/BA.5. Since September 2022, a single bivalent booster dose has been recommended for adults who have completed a primary vaccination series and are at high risk for severe Covid-19 disease. Evidence regarding the effectiveness of the bivalent vaccine in reducing hospitalizations and death due to Covid-19 is warranted.
Methods: This retrospective cohort study included all members of Clalit Health Services, aged ≥65, eligible for a bivalent booster. Hospitalizations and death due to Covid-19 among participants who received the bivalent vaccine were compared with those who did not. A Cox proportional-hazards regression model with time-dependent covariates was used to estimate the association between the bivalent vaccine and Covid-19 outcomes while adjusting for demographic factors and coexisting illnesses.
Findings: A total of 622,701 participants met the eligibility criteria. Of those, 85,314 (14%) received a bivalent-booster during the 70-day study period. Hospitalization due to Covid-19 occurred in 6 bivalent recipients and 297 participants who did not, adjusted hazard ratio (HR): 0.19 (95% CI, 0.08-0.43). Death due to Covid-19 occurred in 1 bivalent recipient and 73 participants who did not, adjusted HR 0.14: (95% CI, 0.02-1.04).
Interpretation: Participants who received the bivalent vaccine had lower hospitalization and mortality rates due to Covid-19 than non-recipients up to 70 days after vaccination.
It's time to admit you and this study weren't ready for prime time analysis.
Everyone in this study had to be eligible for the booster which presumably means they were already vaccinated.
Independent of the unknown dangers of a shot rate reaching that frequency, which you haven't yet addressed.
We've given well over half a billion shots in the US and I haven't seen an increasing rate of any particular problems. Absence of evidence isn't evidence of absence but given the number of multiply vaccinated people I'd expect to see a problem if there were one.
You want to discard this study because I don't know what Israel's booster eligibility requirements are off the top of my head?
Whatever gets you through the night.
Nobody under 70 and is healthy, and who has previously had Covid needs ANY Covid Vaccination.
The odds of them having a “severe outcome” is already less than the bivalent vaccinated that has never had Covid, especially over 3 months after the injection.
Vaccinating the previously infected is going to go down as one of the dumbest things we have ever done.
A strong pronouncement, that many here would disagree with, to say the least.
Source?
73 deaths/537,837 unboosted vs 1 death/ 85,314 boosted
85K is 1/6th of 537K so 1x6 gives 73 vs 6
from the pre-print: “study commenced on Sep. 24, 2022, when the bivalent vaccination campaign was initiated in CHS. The bivalent vaccine supplier was Pfizer-BioNTech. Participants were followed until Dec. 12, 2022, and for at least 14 days after vaccination. The data extraction date was Dec. 14, 2022”
https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4314067
comorbidities included asthma, CHF, CRF, COPD, Diabetes, Hypertension, IHD, obesity, history of CVA and history of smoking
I haven't discarded it at all. I've actually conceded your claimed results - improvement to symptoms for 70 days.
What has been discarded, have been my questions, regarding the practicality of injecting all Americans every 70 days, and the possible dangers of that many shots in just a single year.
Did you address those questions yet, or not?
303 total hospitalized out of 85,000?
Maybe with IVM early treatment it would be almost -zero-
the study period ran 70 days. That doesn’t mean the booster only lasts 70 days. See my post #27
But to answer your question, if I were uber high risk and over 65, and a pandemic in my area was burning thru old people like fire through a lumber mill, I’d be looking at anything that might perserve my life given my own strong instinct to survive. I might think differently were I aged 25.
I never said it did. But that is the only published and approved result of the study. Therefore, anything else is supposition. If you want to claim any level of effectiveness on the 71st day, you need data to support it. Thanks.
Ivermectin and hcq works for me - no vaccine injuries nor deaths
They would disagree that I haven't seen a lot of problems?
How would they know what I've seen?
I am 70 and my wife 69. We both had it 11 months ago. We both have not the the Jab that is not a vax. We are both in good health. We both will NEVER get ANY mRNA jab masquerading as a vaccine.
Eff the FDA, the CDC, Pfizer et al. I would not believe any of them if they said it was high noon unless I went outside and saw it myself.
So the source you present to defend this study is .... yourself.
Got it.
I think just about any vaccine ups one’s immunity in the short term, but I’m betting after 2 months the immunity is gone. The BCG vaccine for tuberculosis also seems to provide some immunity against covid, even though there’s no relationship between the two.
https://pubmed.ncbi.nlm.nih.gov/34742127/
What are you talking about?
For one, I'm not "defending" the study. It is what it is and if the authors' peers want to find fault with it, fine.
More to the point, it wasn't the study I was commenting on - it was your hobby horse issue of risk from repeated shots. As you were insistently demanding that I do.
You throw out an issue, present no evidence to indicate it's a problem, demand I address it, then falsely pretend I'm attempting to be some sort of authority.
Grow up and debate honestly.
The don’t talk about the increase in deaths from other causes such as heart attacks and strokes. Cancers, and autoimmune diseases.
Japan is reporting all time high Covid death counts and they are thoroughly vaxed.
China . . . is sort of “reporting”. They have a different definition of Covid death. Unlike all other countries of the world, they require respiratory failure to declare a Covid death, and this is near impossible with ventilators, and explains their tiny death numbers.
But regardless of that, the BBC’s reporters have visited Chinese hospitals and found them packed with patients overflowing into the hallways. And their crematoriums are on triple shifts. BBC estimates 15,000 Covid death per day by international WHO definitions of a Covid death.
And they are thoroughly vaxed. Sinovac, Sputnik V, Astrazeneca and Covaxin. These are all just as useful as the mRNA vaxes. They do not, however, demonstrate a bivalent booster dataset — which largely doesn’t matter because the US is far less boosted than the original vax %.
China . . . is a big problem. We should have be slammed by what is happening in China by now. Overdue.
Do you have any data on this increase?
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