Free Republic
Browse · Search
General/Chat
Topics · Post Article

Skip to comments.

Testosterone is an ally of macrophages in the battle against adrenal cancers (Administering it could help women fight it)
Medical Xpress / CNRS / Science Advances ^ | Oct. 14, 2022 | James Wilmouth et al

Posted on 10/16/2022 6:23:08 PM PDT by ConservativeMind

Why are cancers of the adrenal glands more common among women? Why are prognoses worse for them? A team of scientists led by a researcher answers these questions.

They demonstrate that, in male mice, there is greater recruitment of immune cells known as macrophages, which can eliminate tumor cells. Hence, aggressive tumor progression is scarcely seen in male mice; while in female mice, macrophages do not slow the growth of tumors, which eventually metastasize. Through molecular analyses, the team determined that recruitment of tumor-fighting macrophages depends on testosterone.

After simple administration of the hormone to females, macrophages able to eradicate tumor cells were rallied to battle. On the basis of these findings, the scientists conducted another study using data on humans, which revealed the same difference in macrophage recruitment rates between men and women with adrenal cancers.

This discovery suggests the potential of hormonal stimulation as a treatment for this type of cancer, whose five-year survival rate is less than 30%.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS:
In men, this cancer is able to be fought by the body.

It’s good to know a common treatment could be helpful for women.

1 posted on 10/16/2022 6:23:08 PM PDT by ConservativeMind
[ Post Reply | Private Reply | View Replies]

To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20 - 25% fewer pings) or “Everything” list.

2 posted on 10/16/2022 6:23:57 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: ConservativeMind

That could produce interesting side effects to say the least.


3 posted on 10/16/2022 7:05:25 PM PDT by Theophilus (It's fake and defective)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Theophilus

No, probably not...women need testosterone too...as long as it is in balance with other hormones.


4 posted on 10/16/2022 7:22:28 PM PDT by goodnesswins (The Chinese are teaching calculus to their 3rd graders while ours are trying to pick a pronoun.)
[ Post Reply | Private Reply | To 3 | View Replies]

To: goodnesswins

Tney dont need extra though. Aga8n extra mess3s with balance.


5 posted on 10/16/2022 8:45:12 PM PDT by Secret Agent Man (Gone Galt; not averse to Going Bronson.)
[ Post Reply | Private Reply | To 4 | View Replies]

To: Theophilus

Interview with a female bodybuilder. Average man has 25-50 times testosterone as average woman. Female bodybuilder was doping with T. They only gave her enough to double her own natural level. So she’d be 12-25 times less than an average man.

She came right out and said she had no idea how men are able to control themselves. Just with double her T, she said she was a lot more angry, picking fights, pissed off, and very horny. Her words. She had no idea how guys make it through the day without losing it.

So no, extra T really isn’t great idea for the less stable sex.


6 posted on 10/16/2022 8:50:38 PM PDT by Secret Agent Man (Gone Galt; not averse to Going Bronson.)
[ Post Reply | Private Reply | To 3 | View Replies]

To: Secret Agent Man

Read later.


7 posted on 10/16/2022 8:52:12 PM PDT by NetAddicted (Just looking)
[ Post Reply | Private Reply | To 6 | View Replies]

To: Secret Agent Man
Too little also messes with your balance.

For one thing you do not heal properly or build muscle.

If your level is low you should try losing weight and lifting weights to bring it up naturally.

Any sort of supplements should be as a last resort but never taken off the table.

8 posted on 10/16/2022 9:10:27 PM PDT by Harmless Teddy Bear (The nation of france was named after a hedgehog... The hedgehog's name was Kevin... Don't ask)
[ Post Reply | Private Reply | To 5 | View Replies]

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
General/Chat
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson