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Researchers examine the role of low-carb, low-sugar diets in warding off polycystic kidney disease
Medical Xpress / University of California - Santa Barbara / Clinical Kidney Journal ^ | June 7, 2022 | Sonia Fernandez / Albert C M Ong et al

Posted on 09/02/2022 9:06:32 PM PDT by ConservativeMind

Thomas Weimbs published a clinical study that gives the first indication that ketogenic diets may be safe and effective in patients with polycystic kidney disease (PKD). The idea to use such diets originated from a mouse experiment. Giving less food to lab mice whose genomes were manipulated to give them PKD led to a vast improvement in their kidney disease. The stunning effect was the metabolic state of ketosis.

Putting lab animals into ketosis using ketogenic diets, intermittent fasting, or administering the ketone beta-hydroxybutyrate (BHB) all produced the same effect. The result was so stark the researchers had to double check the animals' genotypes to make sure they hadn't made some mistake. But there it was: Ketosis, a fasting response that is also the basis of popular diets, actually shrank the kidney cysts in animals.

Now, Weimbs and colleagues take a closer look at the real-life experiences of a cohort of patients with autosomal dominant PKD (the more common form) who have undertaken ketogenic dietary interventions. It's an effort to gain a clearer picture of how ketogenic and time-restricted diets can be used to manage this disease.

Their conclusion? Ketogenic dietary interventions "may be safe, feasible and potentially beneficial for autosomal dominant PKD patients," according to the researchers.

Weimbs was "actually very positively surprised" by the outcomes reported from the surveys. "I was almost stunned by how clear-cut these data were," he said.

According to the study, a total of 86% of participants reported that the dietary interventions improved their overall health. Additionally, 67% of those surveyed described improvements in their ADPKD-related health issues, while 64% reported improvements in blood pressure. A full 90% observed significant weight loss, and 92% reported the interventions as feasible, though 53% took breaks from their diets, often due to practical difficulties.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: mkl; pkd
From the write up:

“Putting lab animals into ketosis using ketogenic diets, intermittent fasting, or administering the ketone beta-hydroxybutyrate (BHB) all produced the same effect.”

I’d suggest the first two options, as a lot of carbs and BHB likely don’t mix well.

Good news for polycystic kidney disease sufferers.

1 posted on 09/02/2022 9:06:32 PM PDT by ConservativeMind
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To: Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ProtectOurFreedom; matthew fuller; ...

The “Take Charge Of Your Health” Ping List

This high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Email me to get on either the “Common/Top Issues” (20% fewer pings) or “Everything” list.

2 posted on 09/02/2022 9:07:20 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

One more nutty diet for fat chicks to obsess about.


3 posted on 09/02/2022 9:12:19 PM PDT by anton
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To: ConservativeMind

More than half the doctors won’t like it. They still give you the low calorie plant based crap. But low carb diets and fasting work. And you can easily cure Diabetes 2 as well. Plus your risk of strokes and heart attacks go way down. You should eat less than 50 grams of carbs everyday. And you should fast every once in a while. You can fast simply by skipping breakfast and just having black coffee or tea in the morning.


4 posted on 09/02/2022 9:17:35 PM PDT by poinq
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To: ConservativeMind

Another feather in Keto’s cap (or something like that).

Gonna be a bummer, though, as Keto is meat-centric and meat, particularly beef/steak/etc. is on the elimination list of the Globalists, as the Dutch and now Canadian farmers are learning the hard way.


5 posted on 09/02/2022 9:48:20 PM PDT by BobL (The Globalists/Neocons desperately want Ukraine to win...makes it easy for me to choose a side)
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To: poinq

“And you can easily cure Diabetes 2 as well.”

Not quite ‘cures’ Diabetes, but does reverse it - meaning getting blood sugar back to normal as long as you eat healthy.

Curing diabetes would mean you could go back to junk food (high carb, low fat), but if you were diabetic (Type 2, of course), and go back to junk food, you’ll get your high blood sugar back.

So, once diabetic, as I understand it, you pretty much have to stay with healthy food (low to very low carb, high fat, particularly high saturated fats), for life.


6 posted on 09/02/2022 10:13:37 PM PDT by BobL (The Globalists/Neocons desperately want Ukraine to win...makes it easy for me to choose a side)
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To: BobL

It works for me. I hit upon this about four years ago. I refer to this as low tech solutions to nasty little problems. And this couldn’t be any more low tech. Just stop eating stay away from carbs. Add in butyrate. I never went into ketosis but I was doing strong intermittent fasting. I had a 30% improvement in my kidney function and my kidney doctor never asked me what I did. Viome has helped me with this.


7 posted on 09/02/2022 10:16:51 PM PDT by magua (It's not racism, it's just that thisBecause it’s being reported that a lot of this started in 2015.)
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To: BobL

By cures I mean you can go without medication. Your carb binging days are gone forever. But if you keep your carbs very low, under 20 grams a day, you can ween off insulin. And after a year or two you can work your way back to 50 grams of carbs a day. Most Americans eat over 200 carbs a day. A bowl of cereal or a bagel, a Hamburger Bun and fries, beer or sweet drink. Then throw in some snacks and noodles or rice with dinner. The standard American diet will kill you in the end.


8 posted on 09/03/2022 5:45:38 AM PDT by poinq
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To: magua; ConservativeMind

the key to getting more butyrate in your life is to eat keto bread. that bread is made of flours like almond flour or coconut flour or any of a dozen different flours that the stomach and small intestine can’t digest. the flours are all digested in the large intestine and bowls by the bugs. keto bread is basically bug food. bugs make the butyrate and other short chain fatty acids that the body needs.

There’s a growing body of evidence that US diet just doesn’t include enough bug food.


9 posted on 09/03/2022 5:46:49 AM PDT by ckilmer (qui)
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To: ckilmer

Butyrate can be found in the following products Jerusalem artichokes, chicory root and jicama. Also you can buy a product called ,pre-biotin prebiotic, its load it with inulin from chicory root. $30.00 Amazon


10 posted on 09/03/2022 6:38:40 AM PDT by magua (It's not racism, it's just that thisBecause it’s being reported that a lot of this started in 2015.)
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To: ckilmer; metmom

I do agree that keto bread/tortillas are a good way to get forms of soluble fiber/resistant starch. Also, inulin, with daily amounts of 20 grams or less, is good.

Green bananas and cold baked potatoes also have other resistant starch forms.

Cellulose is not a good fermentable starch.

Items with “Modified Wheat Starch,” which includes keto breads, should be okay.


11 posted on 09/03/2022 9:56:12 AM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

I read a study about what was in the cyst that are attached to our kidneys and liver. There’s glucose and salt in the cyst. As you reduce your glucose intake the body will start searching for glucose wherever we can find it. your muscles store it and anywhere else in your body . Fasting the body will help draw out the glucose and reduce the size of the cyst. Exercising while fasting will also reduce the glucose inside your body faster. No one‘s going to tell you that not even your kidney doctor. There’s a clinic in California called Northwest which takes people and has them fast for a minimum of five days. They were started in 1985 and have never lost a patient but fasting is the way they get to the patient where they want the patient to be in the fastest amount of time. Also check out on YouTube Jason Fung from Toronto he has helped more people with kidney problems than anyone going. And he believes in fasting also. There’s to much information available. Genetics load the gun lifestyle pulls the trigger. something is going to get you don’t let it be you. This is controllable.
.


12 posted on 09/03/2022 10:58:54 AM PDT by magua (It's not racism, it's just that thisBecause it’s being reported that a lot of this started in 2015.)
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To: ConservativeMind; metmom

I have taken to adding some oat figer and teff to the bread in small amounts to make it rise better and give it a more bread feel. but these are not resistant starches. I may replace them with some tuber flours.


13 posted on 09/03/2022 12:35:07 PM PDT by ckilmer (qui)
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