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Metabolism may be key to future treatment of kidney diseases (Lysine helps)
Medical Xpress / Aarhus University / Nature Communications ^ | August 19, 2022 | Markus M. Rinschen et al

Posted on 08/20/2022 10:45:19 PM PDT by ConservativeMind

Can you eat your way out of a kidney disease? Perhaps you can—according to a new study.

Associate Professor Markus Rinschen has shown that the intake of the amino acid lysine, an over-the-counter food supplement, protects laboratory animals from kidney damage.

The study was primarily conducted on rats with high blood pressure—hypertension—and associated kidney disease. But a small pilot study confirms that the amino acid could have similar effect in humans, without definite evidence for clinical effects on kidney disease.

"We discovered that there is an accelerated transformation of the amino acid lysine in humans and animals with kidney disease. And the study shows that the intake of lysine protects the kidneys and prevents hypertensive kidney disease rather effectively, at least in animal models," explains Markus Rinschen.

It is estimated that up to 10% of the adult population suffers from chronic kidney disease, although often mild and without symptoms. The most frequent causes of kidney disease and kidney failure are diabetes or high blood pressure, and the consequence is a much higher risk of heart attack or stroke.

"It would be great if kidney patients could achieve results by changing their diet," says Markus Rinschen.

"We want to understand kidney metabolism, and this is a big step. Giving patients a substance they already have in their body and creating clinical results would be a new and surprising discovery," says the researcher, who hopes that the study can lead to a more general understanding of beneficial metabolites.

"The study shows how dynamic and unexplored our metabolism still is, and that we need holistic approaches to understand it. Diet, metabolism, heart and cardiovascular system—many things contribute to the development of kidney disease."

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: kidney; kidneydisease; lysine; metabolism
You can get lysine from meat and dairy products, followed by beans.

It is also available as a supplement.

1 posted on 08/20/2022 10:45:19 PM PDT by ConservativeMind
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To: Pete from Shawnee Mission; Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ...

The “Take Charge Of Your Health” Ping List

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2 posted on 08/20/2022 10:45:48 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind
wouldn't be marvelous if we could discover a cure for kidney disease...Kidney disease comes on slowly so there would be time for early treatments...

then again, Kidney dialysis is BIG business, like cancer treatments.

3 posted on 08/20/2022 10:50:33 PM PDT by cherry
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To: ConservativeMind

Thanks. General reports conclude most people get enough lysine in their diet and don’t need supplements. Too much lysine supplement is associated with kidney stones.


4 posted on 08/21/2022 2:56:01 AM PDT by Hostage (Article V)
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To: ConservativeMind

Bfk


5 posted on 08/21/2022 5:05:27 AM PDT by Impala64ssa (If a liar's pants really did catch on fire CBC, ABC, CNN and MSNBC would be more fun to watch)
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To: ConservativeMind

Bookmark


6 posted on 08/21/2022 11:06:06 AM PDT by Irish Eyes
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