He was a 350 pound junkie.
Not even the best of genes can overcome that life choice.
true..but genetics could have played a part in that..and probably did. Nature and Nurture.
For example, here is an interesting study. These things are very difficult to prove:
Reference papers and your DNA
Associations between FTO rs9939609 polymorphism, serum vitamin D, mental health, and eating behaviors in overweight adults.
Results of the association analysis between rs9939609 and eating behaviors revealed that participants with AA genotype showed a higher EE score than those with the TT genotype after considering important confounding variables.
Or mental health ones
The Impact of the FKBP5 Gene Polymorphisms on the Relationship between Traumatic Life Events and Psychotic-Like Experiences in Non-Clinical Adults.
Supposedly according to the medical examiner’s report he weighed around 235 to 240 lbs. The 350 pound weight reported was inaccurate due to the bloating affecting his appearance in his last public photos.