Posted on 06/26/2022 4:02:30 PM PDT by ConservativeMind
Patients with advanced kidney cancer who received a new combination treatment reported health-related quality of life outcomes that were either similar or improved, compared to patients who received standard first-line therapy, according to a study.
The findings underscore the potential for the new treatment combination in improving patients' course of treatment and extending survival, said David Cella, Ph.D.
"Effective treatment options have never been better for this disease. Patients' reports of how they are feeling and functioning is certainly meaningful to them, and also can help clinicians when guiding continued quality care," said Cellaz
Advanced kidney cancer occurs when cancer cells inhibit the inner lining of kidney tubules, which help filter and clean the blood. Over the years, treatments for the disease have improved, transitioning from biologic response-modifying drugs to more targeted therapies such as tyrosine kinase inhibitors and mTOR inhibitors.
More recently, the addition of immunotherapy treatments, which are often combined with tyrosine kinase inhibitors, have further improved patient quality of life and survival.
Results from the phase III CLEAR study demonstrated that patients with advanced kidney cancer who were given a tyrosine kinase inhibitor (lenvatinib) plus immunotherapy (pembrolizumab) demonstrated improved progression-free survival and overall survival compared with patients who received a tyrosine kinase inhibitor (sunitinib) alone.
In the current study, Cella and his team assessed health-related quality of life outcomes (HRQOL) scores from the CLEAR study patients. These scores comprised patient-reported disease symptoms, side effects from treatment, and aspects of everyday functioning and general perceptions of life quality and enjoyment.
Overall, the investigators found that patients given lenvatinib plus pembrolizumab treatment had similar or favorable HRQOL scores compared to patients given sunitinib alone. The findings suggest that the combination treatment may be a promising first-line therapy for advanced kidney cancer, according to the authors.
(Excerpt) Read more at medicalxpress.com ...
Maybe Bill gates should spend all that money he wastes on Fake Beef making Real Organs
for anyone fighting cancer I just saw this song from the girl who was America’s Got Talent. She had an amazing outlook on life..
https://www.youtube.com/watch?v=G6UzrJrkpwQ
She did lose her fight with cancer but I hope I can have her outlook if I get ever get the Big C. I thought I was going to get it last year and pathology said you have escaped this time.
“You can’t wait until life isn’t hard anymore before you decide to be happy”-
Nightbirde
Bookmark
Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.