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Type 2 diabetes accelerates brain aging and cognitive decline (26% acceleration in decline)
Medical Xpress / eLife ^ | May 24, 2022 | Botond Antal et al

Posted on 05/24/2022 12:44:40 PM PDT by ConservativeMind

Scientists have demonstrated normal brain aging is accelerated by approximately 26% in people with progressive type 2 diabetes compared to individuals without the disease.

The authors evaluated the relationship between typical brain aging and that seen in type 2 diabetes, and observed that type 2 diabetes follows a similar pattern of neurodegeneration as aging, but one that progresses faster. One implication of this is that even typical brain aging may reflect changes in the brain's regulation of glucose by insulin.

The results further suggest that by the time type 2 diabetes is formally diagnosed, there may already be significant structural damage to the brain.

Their analysis showed that both aging and type 2 diabetes cause changes in executive functions such as working memory, learning and flexible thinking, and changes in brain processing speed. However, people with diabetes had a further 13.1% decrease in executive function beyond age-related effects, and their processing speed decreased by a further 6.7% compared to people of the same age without diabetes.

The team also compared brain structure and activity between people with and without diabetes using MRI scans. They found a decrease in gray brain matter with age, mostly in a region called the ventral striatum—which is critical to the brain's executive functions. Yet people with diabetes had even more pronounced decreases in gray matter beyond the typical age-related effects—a further 6.2% decrease in gray matter in the ventral striatum, but also loss of gray matter in other regions, compared with normal aging.

Together, the results suggest that the patterns of type 2 diabetes-related neurodegeneration strongly overlap with those of normal aging, but that neurodegeneration is accelerated. Moreover, these effects on brain function were more severe with increased duration of diabetes. In fact, progression of diabetes was linked with a 26% acceleration of brain aging.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: brainfunction; diabetis; iylm; neurodegeneration; type2diabetis
Please work to get your diabetes under control, or even better, put it into full remission, as many more are finding out they can, thanks to low carb/keto dieting.
1 posted on 05/24/2022 12:44:40 PM PDT by ConservativeMind
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To: Pete from Shawnee Mission; Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ...

The “Take Charge Of Your Health” Ping List

This potentially high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to immediately implement for your benefit.

Now keeping a new list (“Common/Top Issues”) for conditions expected to only concern at least 1% of the population. Ask to be on either the “Common/Top Issues” or “Everything” list.

Please email or private message me if you want on or off of a list and of which list you desire.

2 posted on 05/24/2022 12:45:32 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

Wow. 26 per cent. That’s a pretty exact figure for something that can’t be measured accurately in the first place,


3 posted on 05/24/2022 12:49:02 PM PDT by Seruzawa ("The Political left is the Garden of Eden of incompetence" - Marx the Smarter (Groucho))
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To: ConservativeMind

Or....you can get rid of it by proper dosing of chromium and vanadium, and by cutting out the Sad American Diet (SAD).


4 posted on 05/24/2022 12:50:44 PM PDT by Salvavida
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To: ConservativeMind

I am hopeless as far as changing diet, but easily keep my pre-diabetes under control with berberine.


5 posted on 05/24/2022 12:52:34 PM PDT by steve86 (Prophecies of Maelmhaedhoc O'Morgair (Latin form: Malachy))
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To: Seruzawa

Without a timeframe they eventually are almost always right.

But what do I know, I have a rapidly aging brain.


6 posted on 05/24/2022 12:52:58 PM PDT by DannyTN
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To: ConservativeMind

Thanks ConservativeMind, I guess I better work harder on it.


7 posted on 05/24/2022 12:55:15 PM PDT by DannyTN
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To: ConservativeMind

It’s a good thing my brain started out 200% better than most, now, with my Type 2 and being 73 I’m only at 174%. Now, what was I going to do in my office?


8 posted on 05/24/2022 1:04:58 PM PDT by Auntie Dem (Hey! Hey! Ho! Ho! Terrorist lovers gotta go!)
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To: ConservativeMind

So, was this for all type 2 diabetes or just uncontrolled diabetes. Mine is in remission. Inquiring minds want to know.


9 posted on 05/24/2022 1:05:33 PM PDT by Whatever Works
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To: Auntie Dem

I was always a kid at heart.

With Diabetes, I should be approaching my teenage years.


10 posted on 05/24/2022 1:23:28 PM PDT by DannyTN
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To: ConservativeMind

Yet another good reason not to be fat.


11 posted on 05/24/2022 1:23:55 PM PDT by glorgau
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To: ConservativeMind

I’m screwed.


12 posted on 05/24/2022 1:24:38 PM PDT by null and void (We're trapped between too many questions unanaswered, and too many answers unquestioned...)
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To: ConservativeMind

More and more I am hearing Alzheimer’s referred to as “Type 3 Diabetes”


13 posted on 05/24/2022 3:01:17 PM PDT by MrFred
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To: ConservativeMind

According to Dr. Annette Bosworth (Dr. Boz on youtube), ketones and sleep can repair a damaged brain. It’s a slow process, like a year or so.


14 posted on 05/24/2022 6:25:16 PM PDT by JohnnyP (Thinking is hard work (I stole that from Rush).)
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