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Calcium supplements linked to earlier death in older people with heart valve disease (Observational and Vitamin K status not known, but many more with diabetes and statin use took supplements)
Medical Xpress / British Medical Journal / Heart ^ | Apr. 25, 2022 | Jutta Bergler-Klein et al

Posted on 04/30/2022 11:53:56 AM PDT by ConservativeMind

Calcium supplements are linked to a heightened risk of death among those with aortic valve stenosis, a progressive and potentially fatal condition, finds research.

What's more, these supplements seem to worsen the condition, irrespective of whether or not they are combined with vitamin D.

Aortic stenosis occurs when the aortic valve, the main outflow valve of the heart, stiffens and narrows. This means it can no longer open fully, reducing or blocking blood flow from the heart into the rest of the body.

…Participants were divided into those not taking any supplements (1292;49%), those supplemented with vitamin D alone (332;12%), and those given calcium plus or minus vitamin D supplements (1033;39%),115 of whom took just a calcium supplement.

Those taking supplements had significantly more diabetes and coronary artery disease than those not taking supplements. They were also more likely to be taking statins, warfarin, and phosphate binders (to limit phosphorus absorption), to have had a coronary artery bypass graft and to need kidney dialysis.

Supplemental vitamin D alone didn't seem to affect survival. But supplemental calcium plus vitamin D was associated with a significantly higher (31%) risk of death from any cause and a doubling in the risk of a cardiovascular death. And it was associated with a 48% heightened risk of AVR compared with those not taking supplements.

Supplemental calcium alone was also associated with a heightened risk of death from any cause (24%) and a near tripling in the risk of AVR. And the risks of death from any cause and from cardiovascular disease were also higher among those taking calcium supplements who didn't have their aortic valve replaced.

Those taking supplements also had more risk factors for heart disease and death than those who weren't and the quantities of calcium intake from diet and supplements weren't assessed.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
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To: gleeaikin

I wasn’t deficient in magnesium. I had flu symptoms, and my mother-in-law suggested it. I don’t remember how much my wife put in. After all that it was Lyme Disease, and that got taken care of with cheap anti-biotics, thank God.


21 posted on 05/02/2022 3:14:07 PM PDT by Dr. Sivana (“...we would live very well without Facebook."-B.LeMaire)
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To: gleeaikin

Long ago I read that one should take calcium with magnesium at about a 2 to 1 ratio.

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Most fruits have the same amount of magnesium and calcium. I don’t take these supplements, but I would take the same amount of magnesium and calcium.


22 posted on 05/02/2022 3:15:59 PM PDT by TTFX
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To: ConservativeMind

How about if one has had a TAVR— trans aortic valve replacement?


23 posted on 05/02/2022 3:22:31 PM PDT by Exit148 (I)
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To: TTFX; ConservativeMind; All

The 2 to 1 ratio is the old standard, but there are new opinions for 1 to 1. Here is the Google page with several choices in both camps.

https://www.google.com/search?q=should+one+take+calcium+and+magnesium+at+a+2+to+1+ratio%3F&rlz=1CAJCUZ_enUS847&oq=should+one+take+calcium+and+magnesium+at+a+2+to+1+ratio%3F&aqs=chrome..69i57j33i160l3j33i299.56330j0j7&sourceid=chrome&ie=UTF-8


24 posted on 05/02/2022 4:05:38 PM PDT by gleeaikin (""s)
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