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Chemical found in leafy greens shown to slow growth of COVID-19 and common cold viruses (Sulforaphane)
Medical Xpress / Johns Hopkins University School of Medicine / Communications Biology ^ | Mar. 23, 2022 | Alvaro A. Ordonez et al

Posted on 03/23/2022 1:38:25 PM PDT by ConservativeMind

In a study, scientists showed that sulforaphane, a plant-derived chemical, known as a phytochemical, already found to have anti-cancer effects, can inhibit the replication of SARS-CoV-2, the coronavirus that causes COVID-19, and another human coronavirus in cells and mice.

Sulforaphane's natural precursor is particularly abundant in broccoli, cabbage, kale and Brussels sprouts. Sulforaphane is derived from broccoli seeds, sprouts and mature plants. Previous studies have shown sulforaphane to have cancer and infection-prevention properties by interfering with certain cellular processes.

In one experiment, the research team first exposed cells to sulforaphane for one to two hours before infecting the cells with SARS-CoV-2 and the common cold coronavirus, HCoV-OC43. They found that low micromolar (µM) concentrations of sulforaphane (2.4–31 µM) reduced the replication by 50% of six strains of SARS-CoV-2, including the delta and omicron variants, as well as that of the HCoV-OC43 coronavirus. The investigators also observed similar results with cells previously infected with the viruses, in which the protective effects of sulforaphane were seen even with an already established virus infection.

The researchers then conducted studies in a mouse model of SARS-CoV-2 infection. They found that giving 30 milligrams of sulforaphane per kilogram of body weight to mice before infecting them with the virus significantly decreased the loss of body weight that's typically associated with virus infection (7.5% decrease). Further, the pretreatment resulted in a statistically significant decrease in both the viral load, or amount of virus, in the lungs (17% decrease) and upper respiratory tract (9% decrease) as well as the amount of lung injury (29% decrease) compared with infected mice that were not given sulforaphane. The compound also decreased inflammation in the lungs, protecting the cells from a hyperactive immune response that seems to be driving factors that has caused many people to die from COVID-19.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
KEYWORDS: sulforaphane
Sulforaphane is available as a supplement.
1 posted on 03/23/2022 1:38:25 PM PDT by ConservativeMind
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To: Pete from Shawnee Mission; Mazey; ckilmer; goodnesswins; Jane Long; BusterDog; jy8z; ...

The “Take Charge Of Your Health” Ping List

This potentially high volume ping list is for health articles and studies which describe something you or your doctor, when informed, may be able to implement for your benefit.

Now keeping a new list (“Common Issues”) for conditions expected to only concern at least 1% of the population. Ask to be on either the “Common Issues” or “Everything” list.

Please email or private message me if you want on or off of a list and of which list you desire.

2 posted on 03/23/2022 1:39:05 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: ConservativeMind

the leafy greens contain a lot of Vitamin K, however...a coagulant that may not be the best thing to have high amounts of in the system with a COVID19 infection.


3 posted on 03/23/2022 1:45:02 PM PDT by Republican Wildcat
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To: ConservativeMind

Mom was right. Again.


4 posted on 03/23/2022 1:45:20 PM PDT by ComputerGuy (Heavily-medicated for your protection)
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To: ConservativeMind
If they found a chemical in red meat that cured cancer they would bury the story under "fake news".

5 posted on 03/23/2022 1:59:26 PM PDT by Governor Dinwiddie (LORD, grant thy people grace to withstand the temptations of the world, the flesh, and the devil.)
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To: ComputerGuy

“Mom was right. Again.”

Agreed

Whoda’ thunk that eating your veggies was good for you?


6 posted on 03/23/2022 1:59:58 PM PDT by Macoozie (Handcuffs and Orange Jumpsuits)
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To: ConservativeMind
Sulforaphane is available as a supplement.

Great, another pill to take every morning.

You measure one's age by the number of pills they take.

7 posted on 03/23/2022 2:01:27 PM PDT by Yo-Yo (Is the /sarc tag really necessary?)
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To: ConservativeMind

Ugh, so I should have gotten Covid since I don’t each broccoli?


8 posted on 03/23/2022 2:05:43 PM PDT by Reno89519 (FJB. Respect America, Embrace America, Buy American, Hire American.)
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To: Republican Wildcat

Regular Use of VKA Prior to COVID-19 Associated with Lower 7-Day Survival in Hospitalized Frail Elderly COVID-19 Patients: The GERIA-COVID Cohort Study.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824717/

If you or a family member are older than 83, you might want to go easy on Vitamin K sources.


9 posted on 03/23/2022 2:06:47 PM PDT by Grampa Dave (Playing “Make Believe” is for children, time to grow up!)
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To: Grampa Dave

Good meal and good health


10 posted on 03/23/2022 2:18:27 PM PDT by ptsal (Vote R.E.D. >>>Remove Every Democrat ***)
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To: Grampa Dave

vitamin K1, or K2?

two totally different mechanisms, as far as I know. K1 interferes with prescribed blood thinners in those with heart disease. K2 doesn’t. however. So what did this study actually test, and was it a double blind study, or one of the silly epidemiological ones that are totally meaningless?


11 posted on 03/23/2022 2:35:22 PM PDT by jacquej ("You cannot have a conservative government with a liberal culture." (Mark Steyn))
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To: ConservativeMind

There goes the price of leafy greens.


12 posted on 03/23/2022 3:02:45 PM PDT by bgill (Which came first, the vax or the virus?)
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To: ConservativeMind

Eat yer spinach and an apple a day keeps Fauci at bay.


13 posted on 03/23/2022 3:06:32 PM PDT by blackdog (Today's "disinformation" most often turns out to be tomorrow's facts. )
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Comment #14 Removed by Moderator

To: Reno89519

Yes. Just punishment comes in time.


15 posted on 03/23/2022 4:48:29 PM PDT by buwaya
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To: blackdog

Also, go outside and play - Vitamin D.


16 posted on 03/23/2022 4:49:08 PM PDT by buwaya
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To: ConservativeMind

they finally found a reason to eat kale


17 posted on 03/23/2022 7:11:34 PM PDT by blueplum ("...this moment is your moment: it belongs to you... " President Donald J. Trump, Jan 20, 2017) )
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To: ConservativeMind

30mg per kg is a HUGE dose compared to typical supplements. It’s like taking a month’s worth every day.

You have to eat about a 100 pounds of broccoli…


18 posted on 03/23/2022 7:37:33 PM PDT by 5by5 (ad)
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