Calorie restriction trial reveals key factors in extending human health (‘Stunning rejuvenation’ of the thymus gland)

Medical Xpress / Yale University / Science ^ | Feb. 10, 2022 | Timothy W. Rhoads et al

[ConservativeMind]

It states the gene most affected might be manipulable by type of diet or just intermittent fasting, or supplement, but that those were not included in their review.

It’s not often you can fully reverse the poor health of an organ.

[ConservativeMind]

The “Take Charge Of Your Health” Ping List

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[gundog]

Do these studies bode well for the future of lab mice? Just wondering. Seems like humans are the new guinea pigs.

[CaptainK]

Is there a number or percentage of calories that you follow to get these benefits?

[goodnesswins]

14% calorie reduction in study...hhhmmmm...I basically put my Hashimotos in remission last year...not sure how, but maybe this, or addition of black cumin seed oil

[blam]

Extend your telomeres...it's that simple.

I do it by taking 2,000 MG of Metformin daily:

Metformin Could Be The Anti-Aging Drug That Lets You Live To 120 Years Old — Here's How

[NWFree]

Yet another reason not to be a fat slob - better T cell production 👍🏻

[Bob434]

I eat 2 meals a day, small meals at that. Hamsandwhich and soda for brunch, then 6-8 ounce steak or chicken and maybe some potatoes or green beans for dinner. I do drink 2 soda a day, and a few smarties for after dinner desert, maybe occasional cookie or two, but usually not. Have eaten this way for all my life really. So my thymus should be golden?

[Karoo]

My husband was on Metformin for several yrs for diabetes. Then very suddenly his MD took him off of it saying that he could die from it if on the medicine too long.

This was around 2009 or so....my memory not the greatest. I mentioned this to someone else and they had never heard of metformin killing people after number of yrs.

FYI

[cherry]

great....I'm on metformin...

but since I'm on the tree bark eating, green swill drinking diet, I'm good.

[erlayman]

I heard the authors saying that none of those made a difference as long as there was CR. Not sure I believe it but even a high fat diet there is only so much you can eat in 4 hours. Exciting that the driver protein is finally being discovered.

[ConservativeMind]

Look into selenium sources with whatever iodine you might need.

People have put Hashimoto’s into remission with selenium and iodine.

[Louis Foxwell]

I have been on metformin for about 20 years. Other things as well, D4, Zinc, etc. Diabetic and heart patient. Otherwise healthy. Need to lose weight. This motivates me.

[goodnesswins]

Thanks...I’ll do that.

[Mount Athos]

https://www.goodrx.com/metformin/long-term-side-effects-of-metformin-what-are-the-risks

He might discontinue if he saw evidence of kidney problem or anemia

[blam]

I've read that people without diabetes out live people with diabetes on average of eight years.

Now, people with diabetes and taking Metformin are out-living the non-diabetic.

Studies have begun in England to test the 'metformin effect' on a large number of non-diabetic people.

[Paisan]

I read many years ago that the secret to long life was COLD & HUNGRY.

Low calorie diet, in a cold climate.

[matthew fuller]

There is a supplement that works just well as metformin, IT IS SAID. Berberine.

[dragonblustar]

Ping.

[steve86]

I take berberine twice a day. I would say its glucose-lowering effects are similar to a low dose of glucophage, but not a high dose.