My husband was on Metformin for several yrs for diabetes. Then very suddenly his MD took him off of it saying that he could die from it if on the medicine too long.
This was around 2009 or so....my memory not the greatest. I mentioned this to someone else and they had never heard of metformin killing people after number of yrs.
FYI
but since I'm on the tree bark eating, green swill drinking diet, I'm good.
I have been on metformin for about 20 years. Other things as well, D4, Zinc, etc. Diabetic and heart patient. Otherwise healthy. Need to lose weight. This motivates me.
https://www.goodrx.com/metformin/long-term-side-effects-of-metformin-what-are-the-risks
He might discontinue if he saw evidence of kidney problem or anemia
Now, people with diabetes and taking Metformin are out-living the non-diabetic.
Studies have begun in England to test the 'metformin effect' on a large number of non-diabetic people.
There is a supplement that works just well as metformin, IT IS SAID. Berberine.