Grapefruit inhibits cytochrome P450. See Grapefruit–medication interactions: Forbidden fruit or avoidable consequences?. Drug doses are calculated with the expectation that P450 is going to degrade a specific amount of the drug before it can be used. Consuming grapefruit knocks out P450 and the undegraded dose may be an overdose.
Do you have any idea how grapefruit interacts with the adrenal genetic variations. Seems like I remember p450 being involved with one of the Adrenal Hyperplasia issues
23 posted on 02/04/2022 6:05:23 PM PST by RummyChick