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Popular blood thinners may lead to brain bleeding after head injury (Use newer blood thinning drugs and no aspirin)
Medical XPress / Radiological Society of North America ^ | Nov. 30, 2021 | Warren Chang, M.D., et al

Posted on 12/02/2021 7:32:23 AM PST by ConservativeMind

A three-year study found that the risk of delayed intracranial hemorrhage and death following head trauma was significantly higher for adults taking older blood thinning medications including clopidogrel (Plavix) and warfarin (Coumadin), according to research. Taking aspirin concurrently with any blood thinner may increase the risk of delayed hemorrhage.

Intracranial hemorrhage occurs when blood vessels within the brain rupture, releasing blood into the brain tissue. In a delayed traumatic intracranial hemorrhage, bleeding in the brain occurs after the initial trauma, usually within 48 hours, after an initial negative head CT.

High blood pressure, head injury and the use of blood thinners are known causes of intracranial hemorrhage.

Adults taking blood thinners who suffer head trauma typically undergo CT imaging of the brain. However, the standard of care beyond initial imaging is not well defined.

"Different hospital networks have different strategies for repeat imaging of these patients," Dr. Chang said.

Within the study group, 576 patients were taking one of the newer blood thinners, such as apixiban (Eliquis), rivaroxaban (Xarelto) and dabigatran (Pradaxa), and 470 patients were taking warfarin, clopidogrel or another older medication.

All deaths in the study group were among patients in the warfarin/clopidogrel/older blood thinner group.

Among the total study group, 345 patients were taking both blood thinners and aspirin. Of the 20 patients who suffered a delayed hemorrhage, 15 were taking an older type of blood thinner, and nine of the 15 were also taking aspirin.

"The rate of delayed hemorrhage was higher in patients taking older blood thinners compared to novel drugs, and significantly higher in patients taking aspirin in addition to the older medications," Dr. Chang said.

Among the five patients taking novel blood thinners who experienced a delayed hemorrhage, four were also taking aspirin.

(Excerpt) Read more at medicalxpress.com ...


TOPICS: Health/Medicine
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To: ConservativeMind

‘The three “newer” blood thinners appear to be over $450 a month.’

that’s after insurance, if I’m not mistaken; I take Eliquis for a-fib, and the cost breakdown on my benefits statement showed the raw price of over $1000 for a 90 day supply...the insurance (UHC) covered all but 250...

I am a pfizer retiree, and I get this drug free, which is a huge deal, because otherwise I’d be taking warfarin, aka rat poison...


41 posted on 12/02/2021 10:15:18 AM PST by IrishBrigade
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To: jagusafr

I’m saddened to hear that.


42 posted on 12/02/2021 10:19:39 AM PST by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: digger48

My docs want me on aspirin in addition to the plavix also. I had been taking aspirin but I began to motice bruising in odd places on my body...like my boobs! And being a diabetic I have to take insulin injections several times a day so I had huge bruises every place I put a needle.

A year and a half ago I got an accidental severe cut on my lower leg and the bleeding was horrendous. I lost 2/3 of a cup of blood in seconds and had difficulty controlling it with a lot of direct pressure.

And the doctor wants me to continue the aspirin! I even quit smoking as they said it was the cause of my problems. Apparently it’s not.

All I know is that if I were in a car accident and got injuries, the likelihood of surviving till the ambulance arrived is very reduced.

I quit the aspirin and the random bruising stopped. I don’t intend to use the aspirin except for pain.


43 posted on 12/02/2021 10:51:51 AM PST by PrairieLady2
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To: ConservativeMind

Taking aspirin with blood thinners is probably not a good idea at all. Even just aspirin taken regularly can make me bleed like a stuck hog.

This study is looks an awful lot like a ploy to sell more and more expensive drugs.

Greed of money knows no bounds. The truth about Fauci book shows him to be a medicine promoter and likely for money.

Nothing wrong with money so long as it is earned for good reason and ethically and legally. In the case of Pfizer and the jab I doubt any of this is true.


44 posted on 12/02/2021 11:37:31 AM PST by Sequoyah101 (Politicians are only marginally good at one thing, being politicians. Otherwise they are fools.I ha)
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To: rlmorel

Could it be motivated by making money on the alternative?

Just a thought.


45 posted on 12/02/2021 11:39:07 AM PST by Sequoyah101 (Politicians are only marginally good at one thing, being politicians. Otherwise they are fools.I ha)
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To: PrairieLady2

Wow. I bruise easy a get scrapes that bleed a lot.

Don’t even know I did it until I see blood running down my hand.

It’s a fine line we have to walk. I was really concerned about getting the jab because of clotting issues. With past history, my doctor was concerned if I didn’t. Didn’t have a problem with it, so...

I’m thankful that I’m not diabetic. It runs in the family.

Along with heart and vascular issues. Heart checks out, but they can’t always find a problem until you have a episode.

Good luck to you.


46 posted on 12/02/2021 11:40:53 AM PST by digger48
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To: kaktuskid

I don’t like grapefruit anyway, but have been told for years not to take anything but Tylenol, which I never take anyway

A small dose of gabapentin for neuropathy, which takes care of some minor aches and pains

Never really tried cbd. My state only allow the weak stuff, so I never saw a point in it


47 posted on 12/02/2021 11:49:34 AM PST by digger48
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To: kaktuskid

That’s what I was told, too. On Eliquis.


48 posted on 12/02/2021 11:50:10 AM PST by MayflowerMadam (When government fears the people, there is liberty.)
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To: Utah Binger

“Eliquis doesn’t have a generic.”

I read that there is a generic, as of a couple years ago. They’re just not letting us have it.


49 posted on 12/02/2021 11:51:38 AM PST by MayflowerMadam (When government fears the people, there is liberty.)
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To: allwrong57

Brain bleed is bad. Sorry for your loss. That is why a Doctor should check you when bumped. He probably did not realize how serious it was.


50 posted on 12/02/2021 11:53:19 AM PST by sport
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To: Ruy Dias de Bivar

That’s interesting. I’ve not known anyone that has been on warfarin that long. Dad and brother had pig valve put in and all three of us have had AAA repair. They got the zipper cut but I was able to do the Stent

I flew for the first time in 35 years last month, and found out that this endoprocethsis must set the damn thing off in security

One of those TSA agents still owes me dinner and drinks for that experience


51 posted on 12/02/2021 11:59:38 AM PST by digger48
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To: Sequoyah101

Absolutely, could well be. Aspirin is cheap and effective for some things, we tend to overlook how good it is because it is so old...

Or, using something like Coumadin as an example, it could be trying to improve a blood thinner in a way that might minimize the problems of a previous medication. It has been a long time for me, but I recall Coumadin has to be carefully tailored and monitored to the individual which involves taking blood tests to see how things are going.

Lots of places to go wrong and have a bleeding problem.

A new medication that would be less “tailored”, require less ongoing monitoring, or be susceptible to serious side effects if things get out of whack wouldn’t be a bad thing.


52 posted on 12/02/2021 12:16:19 PM PST by rlmorel (If the Biden Administration was only stupid or incompetent, some actions would benefit the USA.)
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To: webheart

I’ve had 3 strokes now. I can still function, but can no longer drive due to loss of peripheral vision

Right side works, but can’t feel hot and cold on that side. Burnt the crap out of my index finger on the grill when I first figured that one out

I simply can’t chance another stroke. I wouldn’t want to do it, but I keep a 9mm next to my bed if I have a good hand to use it with

I won’t go to a home and I won’t let my kids have to care for me like that

I already suspect I won’t see the next presidential election, so I’m making what plans I can, while I can


53 posted on 12/02/2021 12:19:43 PM PST by digger48
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To: neverevergiveup

Dad and brother had pig valve and bypasses and pacemaker

Brother has pacemaker/defibrillator.

Neither one needed blood thinner afterwards

At 86, the heart surgery was too much for him. He lost hope and lingered for a year

Brother is 72 and still working in our excavating business, but slowing down


54 posted on 12/02/2021 12:26:01 PM PST by digger48
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To: Utah Binger

After was a concern after my stroke, but a 7 say monitor showed no abnormalities

A late lady friend friend of mine had the Watchman device put in and took care of the afib

She finally passed in home hospice from 12 years of renal failure right when covid hit

I’m glad she went when and how she did, or her family would have had to see her die in a hospital or nursing home without getting to see her

Hard, but a blessing in disguise. She was ready


55 posted on 12/02/2021 12:33:45 PM PST by digger48
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To: aquila48

Me too

Other things only gave me more strokes


56 posted on 12/02/2021 12:36:17 PM PST by digger48
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To: IrishBrigade

Without insurance or GoodRX, eliquis is $495/mo at Kroger

Everyplace else was even higher


57 posted on 12/02/2021 12:41:10 PM PST by digger48
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To: MayflowerMadam

Read that too when I first had to go on it


58 posted on 12/02/2021 12:43:40 PM PST by digger48
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To: rlmorel
Seems lately to be an all out war on aspirin.

Aspirin prevents and/or helps control some types of cancer ( beneficial effects in various cancers, including breast, ovarian, esophageal, and colorectal cancer)....

best drug to take in the "golden hour" getting to a hospitable after having a stroke

- helps prevent heart attacks,

cures headaches,

reduces inflammation,

fights symptoms of colds like high fevers, chills aches and pains,

functions as a blood thinner,

and for all we know aspirin helps with fighting COVID... etc etc etc...AND BOUGHT IN QUANTITY ASPIRIN COST LESS THAN 20 CENTS A PILL...

I have a wild guess why big pharma isn't thrilled it's an over the counter medicine...

59 posted on 12/02/2021 1:06:28 PM PST by GOPJ (Black thugs loot Walgreens:"Oh well" - loot Louis Vuitton-liberals scream 'what the hell'...)
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To: Sirius Lee
Seems lately to be an all out war on aspirin.

Aspirin prevents and/or helps control some types of cancer ( beneficial effects in various cancers, including breast, ovarian, esophageal, and colorectal cancer)....

best drug to take in the "golden hour" getting to a hospitable after having a stroke

- helps prevent heart attacks,

cures headaches,

reduces inflammation,

fights symptoms of colds like high fevers, chills aches and pains,

functions as a blood thinner,

and for all we know aspirin helps with fighting COVID... etc etc etc...AND BOUGHT IN QUANTITY ASPIRIN COST LESS THAN 20 CENTS A PILL...

I have a wild guess why big pharma isn't thrilled it's an over the counter medicine...

60 posted on 12/02/2021 1:08:38 PM PST by GOPJ (Black thugs loot Walgreens:"Oh well" - loot Louis Vuitton-liberals scream 'what the hell'...)
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