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N501Y mutation in SARS-CoV-2 Delta variant is key to breakthrough infections
news-medical.net/news/ ^ | Oct 25 2021 | By Jocelyn Solis-Moreira

Posted on 10/25/2021 10:13:20 PM PDT by BenLurkin

Several issues arose when comparing SARS-CoV-2 samples from breakthrough infections with the rest of the infected community. For instance, the circulation of viral variants changed over time, with Delta being the predominant strain towards the end of the study period. For this reason, collecting samples of breakthrough infections during the study were uneven and heavily focused on the end of 2021.

To address these concerns, the researchers created a Bayesian analysis combining an autoregressive moving average model with multinominal logistic regression. The model accounted for uncertainty and random changes in viral circulation weekly.

The presence of one Delta lineage, B.1.617.2, resulted in a three-fold increase in breakthrough infections.

A common element in SARS-CoV-2 variants involved in breakthrough infections is the N501Y substitution. The N501Y mutation is observed in Alpha, Beta, and Gamma variants.

Prior research on the N501Y substitution has linked it to increased spike protein binding affinity with the ACE2 receptor and decreased binding of human antibodies to the spike protein.

(Excerpt) Read more at news-medical.net ...


TOPICS: Health/Medicine
KEYWORDS: breakthrough; infections; mutation; n501y

1 posted on 10/25/2021 10:13:20 PM PDT by BenLurkin
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To: BenLurkin

there were 4 corona viruses that infected mankind throughout all of history until 1990.

Since then there have been Sars, Mers, Covid19

Although there is no way this could not be a natural normal occurrence, it is fortunate we had forward looking scientists who studied many ways these viruses might become more deadly and jump to Humans,

Some even considered how to make a profit while mitigating damage should this natural evolution ever happen.

Thank God, and Trust the Science.


2 posted on 10/25/2021 10:33:51 PM PDT by algore ( )
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To: algore

Right.

And Lesko Fauxcy is an American Hero....


3 posted on 10/25/2021 10:39:16 PM PDT by Paladin2 (Critical Marx Theory is The SOLUTION....)
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To: BenLurkin
Several issues arose when comparing SARS-CoV-2 samples from breakthrough infections with the rest of the infected community?

Ah, actually no scientist ever even successfully isolated sample of SARS-C0V-2, someone in South Korea claimed they did but it couldn't be replicated to fulfilling or satisfying Koch's postulate.  If they had isolated the virus, they would have been antibody test.

This C0VID thing is all hoax from the gitgo.

Neither is such C0VID-19 asymptomatic transmission.

4 posted on 10/25/2021 11:40:11 PM PDT by wannabegeek (And ye shall know the truth, and the truth shall make you free.)
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To: algore
Although there is no way this could not be a natural normal occurrence,…

Incredibly foolish assertion. The current coronavirus is most definitely human-engineered, rendering your statement false from the start, not to mention questions about the others.

5 posted on 10/25/2021 11:42:01 PM PDT by noiseman (The only thing necessary for the triumph of evil is for good men to do nothing.)
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To: BenLurkin

Ping


6 posted on 10/26/2021 3:04:01 AM PDT by A Formerly Proud Canadian (Ceterum autem censeo Justinius True-dope-us esse delendam)
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To: wannabegeek

Somebody emailed me a meme claiming that. Not sure how it got started when there the technology in use for distinguishing the different strains have been around for a long time.

https://www.cdc.gov/coronavirus/2019-ncov/variants/variant-info.html

https://www.cdc.gov/coronavirus/2019-ncov/variants/cdc-role-surveillance.html

https://www.cdc.gov/coronavirus/2019-ncov/variants/variant-surveillance.html?CDC_AA_refVal=https%3A%2F%2Fwww.cdc.gov%2Fcoronavirus%2F2019-ncov%2Fcases-updates%2Fvariant-surveillance.html


7 posted on 10/26/2021 6:35:09 AM PDT by BenLurkin (The above is not a statement of fact. It is either opinion, or satire. Or both.)
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To: algore

“Some even considered how to make a profit while mitigating damage should this natural evolution ever happen.”

You just know that eventually, it will be discovered that the vaccine companies secretly funded gain of function. Just makes too much sense.


8 posted on 10/26/2021 7:32:49 AM PDT by Basket_of_Deplorables (Convention Of States is our only hope now! Desantis 2024!!!)
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To: BenLurkin
Somebody emailed you, what?

If you have non nonsense brain you'd not believe the bullcrap CDC anymore. She was telling Wolf Blitzer at CNN that there's C0VID-19 asymptomatic transmission, what's up with that. Is there such asymptomatic transmission? Neither aerosol C0VID-19 transmission. You must be paid CDC troll here at FR posting all sorts of BS, and you sold your soul to satan!

9 posted on 10/26/2021 5:35:02 PM PDT by wannabegeek (And ye shall know the truth, and the truth shall make you free.)
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To: BenLurkin
Somebody emailed you, what? Correction, I inadvertently pressed "Post" prematurely.

If you have non nonsense brain you'd not believe the bullcrap CDC anymore. CDC acting director Rochelle Walensk was telling Wolf Blitzer at CNN that there's C0VID-19 asymptomatic transmission, what's up with that. Is there such asymptomatic transmission? Neither aerosol C0VID-19 transmission. You must be paid CDC troll here at FR posting all sorts of BS, and you sold your soul to satan!

10 posted on 10/26/2021 5:37:12 PM PDT by wannabegeek (And ye shall know the truth, and the truth shall make you free.)
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