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Newly discovered biomarker predicts COVID-19 death days in advance
https://newatlas.com ^ | 30 SEPTEMBER 2021 | By Rich Haridy & Mount Sinai

Posted on 10/01/2021 7:26:21 AM PDT by Red Badger

A drop in certain heart electrical activity readings was found to precede COVID-19 death by around 52 hoursvoenkor/Depositphotos _______________________________________________________________________________________

Researchers from The Mount Sinai Hospital have found changes to electrical activity in the heart can help predict which hospitalized COVID-19 patients are more likely to decline and die. The biomarker is easily measurable and potentially predicts death several days in advance.

When hospitals are overwhelmed with COVID-19 patients it can be challenging for doctors to work out where to best focus their limited attention and resources. A number of blood-based biomarkers have been found to help assess those patients most at risk of severe disease decline.

But blood tests take time to be collected and analyzed. This new biomarker can be measured using a simple electrocardiogram (EKG) machine, at a patient’s bedside. And the researchers claim it can predict whether a patient is likely to die at least two days in advance.

A retrospective investigation of health records from 140 COVID-19 patients revealed diminishing QRS waveforms were an indication of a patient declining in 74 percent of cases.

The criteria developed by the Mount Sinai team is dubbed LoQRS, and they propose it to be an effective way of triaging those patients most likely to decline. The median time to death from the first LoQRS reading detected in the study was 52 hours.

“Our study shows diminished waveforms on EKGs over the course of COVID-19 illness can be an important tool for health care workers caring for these patients, allowing them to catch rapid clinical changes over their hospital stay and intervene more quickly,” says Joshua Lampert, senior author on the new study. “With COVID-19 cases and hospitalizations continuing to rise again, EKGs may be helpful for hospitals to use when caring for these patients before their condition gets dramatically worse.”

Interestingly, the researchers also found LoQRS measures were effective in detecting those patients with influenza who were most likely to die. The median time to death from the first LoQRS measure in influenza patients, however, was around six days. The researchers point out this indicates COVID-19 is a much more virulent disease than influenza.

As LoQRS measures can only be detected over time across several EKG tests, Lambert proposes EKG measurements are taken for all COVID-19 patients when they are initially admitted.

“When it comes to caring for COVID-19 patients, our findings suggest it may be beneficial not only for health care providers to check an EKG when the patient first arrives at the hospital, but also follow-up EKGs during their hospital stay to assess for LoQRS, particularly if the patient has not made profound clinical progress,” says Lampert. “If LoQRS is present, the team may want to consider escalating medical therapy or transferring the patient to a highly monitored setting such as an intensive care unit (ICU) in anticipation of declining health.”

The new study was published in the American Journal of Cardiology.

Source: Mount Sinai


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1 posted on 10/01/2021 7:26:21 AM PDT by Red Badger
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To: Red Badger

So I guess they will then know to it is time to stop wasting treatment and discharge you from the hospital?


2 posted on 10/01/2021 7:31:07 AM PDT by Sans-Culotte (11/3-11/4/2020 - The USA became a banana republic.)
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To: Red Badger

Kamala is getting Biden tested as we speak.


3 posted on 10/01/2021 7:31:09 AM PDT by Tell It Right (1st Thessalonians 5:21 -- Put everything to the test, hold fast to that which is true.)
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To: Red Badger

My heart stopped beating three days ago. Should I be worried?


4 posted on 10/01/2021 7:34:25 AM PDT by LIConFem (Read up on Russia's Oct, 1917 Revolution... And prepare.)
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To: LIConFem

No. Your odds of a heart attack are way down now.


5 posted on 10/01/2021 7:35:56 AM PDT by Codeflier (Please stop calling these violent totalitarian collectivist Democrats, liberals. )
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To: Red Badger

The hospitals were said to need fifteen days to prepare for Covid patients.

There has been fifteen months for them to prepare, but instead they are talking about triage?

Are these doctors corrupt, or are they merely incompetent?


6 posted on 10/01/2021 7:36:26 AM PDT by BenLurkin (The above is not a statement of fact. It is either opinion, or satire. Or both.)
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To: BenLurkin

I think they are talking future triages..................


7 posted on 10/01/2021 7:39:40 AM PDT by Red Badger (Homeless veterans camp in the streets while illegal aliens are put up in hotels.....................)
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To: Red Badger

(Bill Bailey sings)

I’ve seen your scans..

Don’t make no plans...


8 posted on 10/01/2021 7:42:15 AM PDT by ASOC (This space for rent)
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To: ASOC

Don’t buy any green bananas.................


9 posted on 10/01/2021 7:43:46 AM PDT by Red Badger (Homeless veterans camp in the streets while illegal aliens are put up in hotels.....................)
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To: ASOC
I’ve seen your scans.. Don’t make no plans...

Please pay your bill in advance.

10 posted on 10/01/2021 7:45:36 AM PDT by redcatcherb412
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To: Red Badger
Here's the original paper in the American Journal of Cardiology:
Prognostic Value of Electrocardiographic QRS Diminution in Patients Hospitalized With COVID-19 or Influenza
"Dynamic QRS amplitude diminution is a strong independent predictor of death over not only the course of COVID-19 infection, but also influenza infection." ... There has likewise been little reported evidence of direct myocardial damage on the 12-lead electrocardiogram (ECG) despite myocardial injury occurring in 33.7% of hospitalized patients. Low QRS amplitude (LoQRS) has been associated with both late gadolinium enhancement on magnetic resonance imaging and cardiac events in clinically suspected myocarditis."
Interesting that the same marker shows up in influenza cases AND in "clinically suspected myocarditis. Mycarditis is what's frequently been noted as affecting and killing some young men and teens receiving the vaccine.
11 posted on 10/01/2021 7:47:56 AM PDT by ProtectOurFreedom (“I believe the best social program is a job” ~ Ronald Reagan)
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To: Red Badger

So when they see the sign, will they finally let vaccinated loved ones come in and hold the hand of the dying patient instead of leaving them all alone? I’m sure my brother would’ve loved to have seen his wife and kids one last time.


12 posted on 10/01/2021 7:52:28 AM PDT by FamiliarFace
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To: BenLurkin
I don't like them saying sound "triage". It's another way of saying "rationing". Don't like that at all.

13 posted on 10/01/2021 7:53:07 AM PDT by Governor Dinwiddie (LORD, grant thy people grace to withstand the temptations of the world, the flesh, and the devil.)
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To: Red Badger

My best attempt at translation (not a doctor, dont play one, do have heart issues)

In a normal heart beat, there is first a normal or base line, then there is a drop followed by a spike. The Q wave is the drop. It is looked at for both duration, and amplitude.

Abnormal Q wave is associated with several issues but the two that are most concerning to me are perimyocarditis and Cardiomyopathy.

More details can be found at: https://ecgwaves.com/ecg-qrs-complex-q-r-s-wave-duration-interval/


14 posted on 10/01/2021 7:55:05 AM PDT by taxcontrol (The choice is clear - either live as a slave on your knees or die as a free citizen on your feet.)
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To: Red Badger

My best attempt at translation (not a doctor, dont play one, do have heart issues)

In a normal heart beat, there is first a normal or base line, then there is a drop followed by a spike. The Q wave is the drop. It is looked at for both duration, and amplitude.

Abnormal Q wave is associated with several issues but the two that are most concerning to me are perimyocarditis and Cardiomyopathy.

More details can be found at: https://ecgwaves.com/ecg-qrs-complex-q-r-s-wave-duration-interval/


15 posted on 10/01/2021 7:55:33 AM PDT by taxcontrol (The choice is clear - either live as a slave on your knees or die as a free citizen on your feet.)
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To: BenLurkin

Maybe the goal of this China bug is to bankrupt the West, trying to save everyone. China probably just shoves them into a hole.


16 posted on 10/01/2021 7:58:06 AM PDT by Empire_of_Liberty
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To: LIConFem

You’re Republican.
You don’t have one!


17 posted on 10/01/2021 7:58:16 AM PDT by tsomer
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To: Red Badger

How many tens of thousands were murdered by intubation?


18 posted on 10/01/2021 8:01:24 AM PDT by montag813
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*


19 posted on 10/01/2021 8:01:27 AM PDT by PMAS (Vote with your wallets, there are 80 million of us - No China made, No Amazon)
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To: montag813

None were murdered by intubation. Would you have merely preferred we not oxygenate someone with critically low oxygen?

I guess you really are the expert. Murder also implies malicious intent. You are a troll. And not a very good one. Go back to drinking to kook aid


20 posted on 10/01/2021 8:09:23 AM PDT by gas_dr (Conditions of Socratic debate: Intelligence, Candor, and Good Will. )
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