Aspirin Use Is Associated With Decreased Mechanical Ventilation, Intensive Care Unit Admission, and In-Hospital Mortality in Hospitalized Patients With Coronavirus Disease 2019

journals.lww.com ^ | Oct 21, 2020 | Jonathan H. Chow, Ashish K. Khanna, Shravan Kethireddy, et al

[ransomnote]

[H/T chuck allen]

Authors: Chow, Jonathan H. MD^*; Khanna, Ashish K. MD, FCCP, FCCM^†,‡; Kethireddy, Shravan MD^§; Yamane, David MD^∥; Levine, Andrea MD^¶; Jackson, Amanda M. MD^#; McCurdy, Michael T. MD^¶; Tabatabai, Ali MD^¶,**; Kumar, Gagan MD^§; Park, Paul MD^††; Benjenk, Ivy RN, MPH^*; Menaker, Jay MD; Ahmed, Nayab MD^§§; Glidewell, Evan MD^∥∥; Presutto, Elizabeth MD^††; Cain, Shannon MD^¶¶; Haridasa, Naeha BS^*; Field, Wesley MD^§§; Fowler, Jacob G. BS^∥∥; Trinh, Duy MD^††; Johnson, Kathleen N. BS^∥∥; Kaur, Aman DO^§§; Lee, Amanda BS^††; Sebastian, Kyle MD^∥∥; Ulrich, Allison MD^††; Peña, Salvador MD, PhD^∥∥; Carpenter, Ross MD^††; Sudhakar, Shruti MD^††; Uppal, Pushpinder MD^††; Fedeles, Benjamin T. MD, Capt, USAF, MC^††; Sachs, Aaron MD^††; Dahbour, Layth MD^††; Teeter, William MD^**,##; Tanaka, Kenichi MD^‡‡‡; Galvagno, Samuel M. DO, PhD^**; Herr, Daniel L. MD^**; Scalea, Thomas M. MD^**,‡‡; Mazzeffi, Michael A. MD, MPH^***Author Information

Anesthesia & Analgesia: April 2021 - Volume 132 - Issue 4 - p 930-941

doi: 10.1213/ANE.0000000000005292

 

EXCERPTS ONLY. DETAILS OF STUDY AT LINK. 

Excerpt: "In summary, our analysis suggests that aspirin use may have beneficial effects in patients with COVID-19. Mechanistically, these findings are plausible given aspirin’s irreversible antiplatelet effect and the frequent hypercoagulability observed in COVID-19 patients. The results of our study are intriguing, especially because aspirin has been thoroughly studied in chronic cardiovascular disease, has a well-described safety profile, and is readily available throughout the world. The preliminary, hypothesis-generating nature of our study provides the basis for a larger study, which will be needed to confirm our findings and assess the extent to which the relationships observed in our study are causal. Until a randomized controlled trial of aspirin is performed, it is imperative to exercise cautious optimism and deliberately balance aspirin’s known risks against its potential benefits in patients afflicted by COVID-19."

 

Aspirin Use Is Associated With Decreased Mechanical Ventilat... : Anesthesia & Analgesia (lww.com)

 

[Qiviut]

If you get COVID, the recommendation I’ve heard recently is to take aspirin for at least 30 days to prevent clotting issues. In Japan, I think they were keeping patients on it for a couple of months after COVID.

As for ‘Tylenol’ (ie acetaminophen) .... when COVID patients present at ER but are not sick enough to be admitted, it’s “go home and take Tylenol”. WRONG, WRONG, WRONG ... as usual. Tylenol depletes glutathione (and it doesn’t take a lot of Tylenol to do it, either) ... glutathione is an essential part of your immune system and also for fighting inflammation. If you want to put yourself in jeopardy quickly, start taking Tylenol when you get COVID.

Endogenous Deficiency of Glutathione as the Most Likely Cause of Serious Manifestations and Death in COVID-19 Patients
https://pubmed.ncbi.nlm.nih.gov/32463221/

If you “google” acetaminophen & glutathione depletion, you’ll get many links if you want to explore this subject further.

[Scarlett156]

Aspirin is truly a miracle drug. A gal I used to interact with at the local convenience store when I lived in the boonies was grieving for her mother. She saw me buying aspirin and observed that bought this a lot and I explained my separated shoulder (motorcycle crash) bothered me sometimes and so I take one or two aspirin every day. She said her mother had done the same until a new doctor at her nursing home made her stop taking it. She said that just a handful of days after her mom stopped taking her daily aspirin, she died of a stroke.

[House Atreides]

Aspirin was the original miracle drug having all kinds of benefits. And new benefits are still being found.

[HamiltonJay]

Wow an anti inflammatory is linked to reducing complications from inflamation. Shocking

[ransomnote]

Wow an anti inflammatory is linked to reducing complications from inflamation. Shocking
~~~~~~~~~~~
The CDC worked so hard to make it seem like ZERO intervention was acceptable. They could have at least admitted to Aspirin.

[ransomnote]

PING

[YouGoTexasGirl]

Only if Ivermectin is not available...!!! Haaa!

[LilFarmer]

FLCCC has been using this in their protocol from day one.

https://covid19criticalcare.com/wp-content/uploads/2020/11/FLCCC-Alliance-I-MASKplus-Protocol-ENGLISH.pdf

[odawg]

“Apparently, I read the headline and thought they were saying the exact opposite.”

It is a clumsy headline.

[livius]

It’s a blood thinner, which is why you’re not supposed to take it before surgery. But a blood thinner is exactly what you need in this case.

[grumpygresh]

Not enough profit. Remdesivir more toxic and profitable. Renal failure, pulmonary edema and ventilators makes more sense. Especially for the unvaccinated.

[plain talk]

What dosage? I noticed low dosage aspirin was mentioned once.

[nuconvert]

My Dr said years ago that all anyone needs for a daily asprin regimen, is one low dose (81mg) a day.
Don’t know what dose the conclusions of this article are referring to.

[plain talk]

Yeah. I am on low dosage aspirin now based on doctor recommendations. Perhaps that is what study used by it is not clear.

[Fresh Wind]

This must be fake news. Everyone knows that aspirin is too cheap to be effective.

[dynachrome]

I’ve been using it in my protocol since getting the moderna “death shots”, so as to be able to see my folks in assisted living.

[Jane Long]

👍🏼🙃

[Jane Long]

Probably not a bad idea.

[Freedom4US]

Overuse is one way to put it, what I read was Aspirin was relatively brand new in 1918 and it does reduce fever. So they were administering “handfuls”. That killed a lot of people.

What I’ve noticed generally in recent years is Aspirin doesn’t seem to be mentioned at all, only Tylenol or Ibuprofin. Not sure why, exacfly.

[RushIsMyTeddyBear]

Yep.