Free Republic
Browse · Search
General/Chat
Topics · Post Article

Skip to comments.

Scientists find a new risk factor for severe COVID-19
Knowridge Science Report ^

Posted on 09/25/2021 8:41:42 AM PDT by House Atreides

In a new study from the University of Kent, researchers found a protein that may critically contribute to severe forms of COVID-19.

SARS-CoV-2 is the coronavirus that causes COVID-19. While many individuals develop only mild or no symptoms upon SARS-CoV-2 infection, others develop severe, life-threatening disease.

Researchers have found that the infection of cells with SARS-CoV-2 results in increased levels of a protein called CD47 on the cell surface.

CD47 is a so-called ‘do not eat me’ signal to the immune system’s defenses that protect cells from being destroyed.

Virus-induced CD47 on the surface of infected cells is likely to protect them from immune system recognition, enabling the production of larger amounts of virus, resulting in more severe disease.

Well-known risk factors for severe COVID-19 such as older age and diabetes are associated with higher CD47 levels.

High CD47 levels also contribute to high blood pressure, which is a large risk factor for COVID-19 complications such as heart attack, stroke, and kidney disease.

In the study, the results suggest that age and virus-induced high CD47 levels contribute to severe COVID-19 by preventing an effective immune response and increasing disease-associated tissue and organ damage.

Since therapeutics targeting CD47 are in development, this discovery may result in improved COVID-19 therapies.

The team says they may have identified a major factor associated with severe COVID-19. This is a huge step in combatting the disease and they can now look forward to further progress in the design of therapeutics.

If you care about COVID-19, please read studies about the cause of COVID-19 lung damage and findings of these drugs may reduce death risk and time in ICU in people with severe COVID-19.

For more information about COVID-19 prevention and treatment, please see recent studies about your immune system mounts a lasting defense after recovery from COVID-19 and results showing that this common drug may reduce death risk in severe COVID-19.

The study is published in Current Issues in Molecular Biology. One author of the study is Professor Martin Michaelis.


TOPICS:
KEYWORDS: chinavirus; covid19; dsj03; immunesystem; thankschinks
Navigation: use the links below to view more comments.
first 1-2021-24 next last
This is very good information and explains one reason why COVID-19 can progress into severe disease. The virus, in effect, can engage in a biological disinformation campaign aimed against the body’s immune system.
1 posted on 09/25/2021 8:41:42 AM PDT by House Atreides
[ Post Reply | Private Reply | View Replies]

To: House Atreides

More proof it’s a democrat/CCP bio weapon.


2 posted on 09/25/2021 8:48:21 AM PDT by cableguymn (We need a redneck in the white house.... But the fact checkers said thein story was false!)
[ Post Reply | Private Reply | To 1 | View Replies]

To: House Atreides

Or, get on ivermectin and HCQ prophylactically.

Not Vaxed.

“Fook Joe Biden!”

clap
clap
clap clap clap

(Repeat)


3 posted on 09/25/2021 8:50:15 AM PDT by Basket_of_Deplorables (Convention Of States is our only hope now! Desantis 2024!!!)
[ Post Reply | Private Reply | To 1 | View Replies]

To: House Atreides

Sounds very legitimate to me. Will fauci and his gang condemn it because it might give people an excuse to not get the fauci ouchie?


4 posted on 09/25/2021 8:54:42 AM PDT by I want the USA back (Dethrone the ruling elite. Redistribute their wealth. Take away their power. Annul their privileges.)
[ Post Reply | Private Reply | To 1 | View Replies]

To: House Atreides

Soooo...what are the “vaxes” doing?


5 posted on 09/25/2021 8:55:02 AM PDT by goodnesswins (The issue is never the issue. The issue is always the revolyution." -- Saul Alinksy)
[ Post Reply | Private Reply | To 1 | View Replies]

To: cableguymn

The CD47 “do not eat me” signaling protein is a defensive measure also employed by cancer cells to prevent destruction by the immune system.

https://www.annalsofoncology.org/article/S0923-7534(19)31086-5/fulltext


6 posted on 09/25/2021 8:56:22 AM PDT by House Atreides
[ Post Reply | Private Reply | To 2 | View Replies]

To: House Atreides

Maybe that’s why I haven’t had it. I’m 66. My BP today was 114/76. My blood sugar when checked at my 6 month checkup was 79. I don’t take BP meds and the only prescription I take is a thyroid pill each day. I try to stay healthy since I do have seasonal asthma. I do my best to avoid all respiratory viruses.


7 posted on 09/25/2021 9:02:57 AM PDT by Tennessee Conservative (My goal in life is to be the person my dog's think I am)
[ Post Reply | Private Reply | To 1 | View Replies]

To: House Atreides

I’ve wondered that if covid causes the body to ‘attack itself’ like an autoimmune disease li,e arthritis, crohn’s or colitis, lupus or whatever, woild folks with autoimmune diseases be at higher risk of getting the serious symptoms? Or would their bodies be too busy fighting off the diseases they have to then focus on covid and damaging organs?

A .ot of folks have an autoimmune disease but don’t even realize,it, and think that they are healthy with. NO issues to speak of, none that have diag owed anyways, I wonder if these are the ‘healthy folks with no preconditions’ that we hear of coming down with covid and xying?


8 posted on 09/25/2021 9:03:39 AM PDT by Bob434
[ Post Reply | Private Reply | To 1 | View Replies]

To: House Atreides

Old news.


9 posted on 09/25/2021 9:06:10 AM PDT by SaxxonWoods (Leave Us Alone.)
[ Post Reply | Private Reply | To 1 | View Replies]

It’s just that Covid-19 has never been isolated and we have no test for it, and 38 million cases of influenza ‘disappeared’ last year, so the scare tactics about Covid are old and busted.


10 posted on 09/25/2021 9:14:43 AM PDT by ransomnote (IN GOD WE TRUST)
[ Post Reply | Private Reply | To 1 | View Replies]

To: SaxxonWoods

“ Old news.”
****************
Well, it was new to me and likely is to many others also. I did a FR search on “CD47” as well as the title of the article and got no hits.


11 posted on 09/25/2021 9:15:00 AM PDT by House Atreides
[ Post Reply | Private Reply | To 9 | View Replies]

To: House Atreides

Very interesting. Maybe something developed can help both cancer and the covid bioweapon


12 posted on 09/25/2021 9:22:32 AM PDT by RummyChick
[ Post Reply | Private Reply | To 6 | View Replies]

To: House Atreides

I’ve read that 90% of those 65 and younger (probably older ones too) who truly suffer the most from covid are very obese. This needs to be discussed more.


13 posted on 09/25/2021 9:25:32 AM PDT by olivia3boys
[ Post Reply | Private Reply | To 1 | View Replies]

To: cableguymn

Would be much more useful if compared to the autopsy of a naturally immune person treated with Ivermectin as a prophylactic to see if these newly ‘discovered’ proteins exist to the same extent as someone ‘jabbed’.


14 posted on 09/25/2021 9:26:29 AM PDT by RideForever (One of the Control Group of the CoVID genetic experiment)
[ Post Reply | Private Reply | To 2 | View Replies]

To: House Atreides

House Atreides, is posing COVID crap all that you do? You might need a life.


15 posted on 09/25/2021 9:29:04 AM PDT by WMarshal ("Those who would give up essential liberty, to purchase a little temporary safety, deserve neither.")
[ Post Reply | Private Reply | To 1 | View Replies]

To: ransomnote

“It’s just that Covid-19 has never been isolated and we have no test for it…”
********************************************************************
Right… and the moon landing was fake and there is no such thing as a CD47 protein. It’s all a big trick the medical and molecular biology scientists are playing on us.

Seriously, I know that your jihad makes you feel compelled to comment, however inanely, but this thread really has nothing to do with vaccines. The information does however perhaps provide some clues to some possible additional treatment approaches for COVID-19 and other viruses that may employ similar defensive mechanisms.


16 posted on 09/25/2021 9:29:28 AM PDT by House Atreides
[ Post Reply | Private Reply | To 10 | View Replies]

To: House Atreides

Interesting.
Hubs and I got it last fall and had mild cases.
Co-workers, younger than us, got it and ended up in hospital. She was able to come back to work after a month but her husband is STILL on supplemental oxygen.
It baffles me that they got it so bad and we old fogies shook it off.
I have often wondered if we were exposed to variants of Covid from working around cattle, but who knows.


17 posted on 09/25/2021 9:29:52 AM PDT by Cloverfarm (Pray for the peace of Jerusalem ...)
[ Post Reply | Private Reply | To 1 | View Replies]

To: Cloverfarm

“… It baffles me that they got it so bad and we old fogies shook it off.…”
****************************************************
Well, having good genetics and coming from “good stock” likely helps.


18 posted on 09/25/2021 9:35:38 AM PDT by House Atreides
[ Post Reply | Private Reply | To 17 | View Replies]

To: ransomnote

Aspirin Use Is Associated With Decreased Mechanical Ventilation, Intensive Care Unit Admission, and In-Hospital Mortality in Hospitalized Patients With Coronavirus Disease 2019

https://journals.lww.com/anesthesia-analgesia/fulltext/2021/04000/aspirin_use_is_associated_with_decreased.2.aspx


19 posted on 09/25/2021 9:35:51 AM PDT by chuck allen
[ Post Reply | Private Reply | To 10 | View Replies]

To: I want the USA back

Sounds great. Unless you have an over active immune system like me and most my family. Stopping the do not eat me flag would give my immune system free reign to kill me. How about just sticking with ivermectin?


20 posted on 09/25/2021 9:35:53 AM PDT by D Rider ( )
[ Post Reply | Private Reply | To 4 | View Replies]


Navigation: use the links below to view more comments.
first 1-2021-24 next last

Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.

Free Republic
Browse · Search
General/Chat
Topics · Post Article

FreeRepublic, LLC, PO BOX 9771, FRESNO, CA 93794
FreeRepublic.com is powered by software copyright 2000-2008 John Robinson