Antibodies from original strain COVID-19 infection don't bind to variants (Spike-only antibodies fail)

Medical XPress / University of Illinois at Urbana-Champaign / Nature Communications ^ | Sept. 20, 2021 | Liz Ahlberg Touchstone / Timothy J. C. Tan et al

[21twelve]

The mRNA “vaccines” are based on computer modelling based on the virus. The original vaccine was dialed up in a few hours.

I’m guessing that these “booster” shots aren’t boosters in the old sense of the term (just using more of the same dead virus), but are really more like a software tweak in the model, which tweaks one’s DNA a bit differently to combat the new change in the virus.

I doubt anybody knows what effects continuous tweaking of one’s DNA will do.

[mewzilla]

If you’d like to get your geek on...

https://www.cdc.gov/flu/about/viruses/types.htm

[Rokke]

Good point.

[jacknhoo]

Ivermectin doesn’t care what virus strain it is.

[SoConPubbie]

my daughter caught COVID 2 times (never vaccinated) may be the reason why.

She lost 10 days of work and is already struggling financially, working in the restaurant business.

1. If she had been vaccinated she'd probably would have gotten COVID-19 more times since the vaccinated seem more likely to catch the variants (See Israel and UK).
2. With regards to her lost work and struggling financially and choice of careers, maybe she should consider a change of her career path?

[Nateman]

Nature does not stand still. Viruses are very adept at evolving due to their huge numbers. A variant resistant to a RNA jab becomes the next wave. Not only that but a variation that actually uses the Antibody as a Trojan Horse is very much a possibility because of the advantage it would give to the virus. It's called Antibody-dependent Enhancement (ADE) and it has happened with other viruses before.

[dfwgator]

Virus finds a way.

[maddog55]

Produced a d Directed by Fauci.

[grumpygresh]

Natural immunity is more than IgG immunity. There are T cells, IgM other cells. Natural immunity is 13x more effective than from vaccines.
Even if natural immunity is reduced with new variants, it’s even more pronounced for the mRNA injections

[packagingguy]

You are right, a scientist on a Rumble video said the same. There is an animal reservoir. It was posted here that it’s in white tail deer, so make sure your venison is well cooked!

[magna carta]

yes I hope she figures out a better career path. She was the more difficult child.

[logi_cal869]

And once again ‘modern medicine’ concedes utter idiocy about natural immunity.

[ifinnegan]

The point is the title is a lie.

[Organic Panic]

I’m doomed. Only fealty to Fauci and repenting for my heresy of the great and mighty Fauci will save me. Jab me Fauci. Good and hard.

[Organic Panic]

What I got from this.... Are new vaccines able to be made from people who were ‘vaccinated’ and got kung flu or is that for people who naturally recovered?

[Grandpa Drudge]

The authors speak to only testing for antibodies to the spike protein, then they say people who actually got COVID-19 have a lot of antibodies to the rest of the virus length.

Here's a neat video from LabCorp that explains the various components of the Covid-19 (SARS-CoV-2) corona virus.

video explanation of corona virus and vaccine differences

https://www.brainshark.com/1/player/labcorp?dm=5&nrs=1&sfsess=%7B!$Api.Session_ID%7D&sfurl=%7B!$Api.Partner_Server_URL_350%7D&fb=0&r3f1=09334d1e121f4755054f2c4e440e0d1f19454a2b17090d0152&custom=semi-quantitative_testing

First, this is a very simplified but very good explanation of the actual SARS-CoV-2 virus particle, and its main components.

1: The nucleocapsid (RNA and N-protein) which is the heart of the virus, that actually overtakes the infected human cell and replicates itself continuously and advances the infection.

2: The shell of the virus, that supports the E-Protein, M-Protein, and others (unnamed, but irrelevant to this presentation)

3: The all important Spike Glycoprotein (S), The spike protein is the actual mechanism the virus uses to attach itself to the ACE2 receptor of a human cell and capture that cell to advance the infection.

Second, the video explains three different "Qualitative" antibody assays, specifically:

1: SARS-CoV-2 nucleocapsid antibody assay (164068) which detects high affinity antibodies to the nucleocapsid (RNA and N-protein) of the actual virus.

2: SARS-CoV-2 antibody IgG Spike assay (164055) which detects Mature IgG antibodies to the Spike protein of the actual virus.

3: SARS-CoV-2 antibody IgM Spike assay (164034) which detects Mature IgM antibodies to the Spike protein of the actual virus.

Third, the video presents the new SARS-CoV-2 Semi-Quantitative Total Antibody, Spike assay, (164090):

The description of this (164090) is a little sketchy in this video, but from other documentation it is clear that it is specifically focused on the modified Spike protein generated by the mRNA vaccines, and its best purpose is to measure the level of antibodies to the vaccine generated Spike protein

Fourth, note in that video that the focus is primarily on the 164090 Spike protein (vaccine generated) assay, and does not focus on "Qualitative" assays, the only assays for natural infection recovery generated antibodies.

There are actually some very important points made in the video discussion of the new "Quantitative" assay (164090).

1: This assay focuses on the Spike (S) protein generated by the mRNA vaccine, and NOT on the nucleocapsid (RNA and N-protein) which is the heart of the virus.

2: The meaning of the number produced by the assay is not yet fully characterized beyond indicating whether the person has antibodies and CANNOT at this time interpreted to indicate immunity.

3: So why was it launched? It is being used in many studies, and will be correlated with a number of different nutralization assays and parameters, making it more flexible in the long term for a post vaccination world.

4: It's available now to all LabCorp customers.

My personal note: I interpreted LabCorp's advertising of this ($10) test as showing whether you had been previously infected and recoverd from Covid-19, and got the test. It clearly does NOT show whether you had been previously infected and recoverd from Covid-19, and that is stated clearly in my test report. I then tried to order the correct qualitative test (164068) and they refused, stating 164068 could ONLY be orderd by doctors.

So what does that mean, and why is it important?

All previous expectations of the mRNA vaccines aside, this video clearly indicates that current measures of antibodies to this vaccine generated spike protein CANNOT be interpreted to provide immunity against Covid-19 infection.

And you just got that straight from the horse's mouth (LabCorp)