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The Japanese Study: The SARS-CoV-2 Delta variant is poised to acquire complete resistance to wild-type spike vaccines (2021.08.22)
https://www.biorxiv.org/content/10.1101/2021.08.22.457114v1.full
1 posted on 09/14/2021 10:20:20 AM PDT by rxsid
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Ping!

Study Shows Vaccine Will ENHANCE Delta Infectivity

2 posted on 09/14/2021 10:20:40 AM PDT by rxsid (HOW CAN A NATURAL BORN CITIZEN'S STATUS BE "GOVERNED" BY GREAT BRITAIN? - Leo Donofrio (2009))
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To: rxsid
Who really knows?

Reminds me of the Dusty Springfield song with words ‘...wishing and hoping and thinking and praying... .’

Call me skeptical.

4 posted on 09/14/2021 10:28:26 AM PDT by hoe_cake
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To: rxsid

This seems likely to ultimately be population reduction posing as inoculation efforts.

Good thing the Nazis did t know about this trick.


5 posted on 09/14/2021 10:28:51 AM PDT by Rurudyne (Standup Philosopher)
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To: rxsid
The numbers we are seeing seemingly contradict the notion that widespread vaccination - coupled with natural immunity - would keep future outbreaks smaller and less deadly. Instead, many states with high vaccination rates- including ones like Vermont, Maine, Washington, and Oregon - are seeing higher case spikes than ever, along with a rise in deaths.

Things are not working out the way they were supposed to. Possibly, as this article suggests, these imperfect vaccines are backfiring and making the problem worse than it would have been without them. Rather than take a pause in the vaccinate-everyone mania, they are doubling-down and becoming more aggressive in mandating vaccinations and demonizing the unvaccinated.
8 posted on 09/14/2021 10:30:01 AM PDT by Steve_Seattle
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To: rxsid

Keep in mind natural immunity will prompt mutations as well.

Welcome to Earth.

It can fester and mutate in the animules as well.


10 posted on 09/14/2021 10:32:09 AM PDT by fruser1
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To: rxsid

Naturally-acquired immunity is clearly superior to vaccine-induced immunity.

However.

Speculation such as “is poised to acquire” is not a “study”, it’s an opinion.


11 posted on 09/14/2021 10:33:18 AM PDT by Jim Noble (The nation cannot be saved until the GOP is destroyed)
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To: rxsid

has Japan gone the ivermectin route?


16 posted on 09/14/2021 10:43:00 AM PDT by joshua c (Dump the LEFT. Cable tv, Big tech, national name brands)
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To: rxsid

What a flaming dumpster fire these vaccines are turning out go be. Just say no.


21 posted on 09/14/2021 10:48:20 AM PDT by BiglyCommentary
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To: rxsid

“Further, according to a team of researchers from the Washington University School of Medicine, if you’ve had COVID-19 — even a mild case — you’re likely to be immune for life, as is the case with recovery from many infectious agents.19”

the money quote—which jibs with everything we’ve learned about infectious pathogens and and our natural, God given, peak functioning, immune system’s defense against them.


22 posted on 09/14/2021 10:52:12 AM PDT by dadfly
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To: rxsid

For those who believe that Biden’s vaccine mandate is the right thing to do and that he has the authority to do it, let me propose a hypothetical. Assuming Biden is sincere and is looking out for Americans, once the precedent is set, what is to stop a future evil president from mandating a vaccine that will cause death and destruction in order to reduce overcrowding or kill off his political rivals? Did they ever think of that?


29 posted on 09/14/2021 11:05:42 AM PDT by Skeptical constituent
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To: rxsid

Thank you for the link to the actual study. So many people see a source and think it’s political. Even the CDC is apparently sort of publicly hedging bets and tiptoeing around the government’s shoving boosters up our skins. Vaccines are not the best way to get rid of this.

Having it go through the population to make the species stronger is the way. Some will die; people are simply not meant to live forever. Devastating on a personal level but no one gets out alive, and we all become stronger when we fight off enemies and keep going.


34 posted on 09/14/2021 11:19:55 AM PDT by Yaelle
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To: rxsid
The Last Post - Geert Vanden Bossche
36 posted on 09/14/2021 11:25:05 AM PDT by Stentor ( )
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To: rxsid

Most of what I read (except many comments from random freepers) tells me the basically same thing. So, I will keep doing the same thing that has worked for me for 18 months.


38 posted on 09/14/2021 11:36:56 AM PDT by SaxxonWoods ( comment might be sarcasm, or not. It depends. Often I'm not sure either.)
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To: rxsid
Study Shows Vaccine Will ENHANCE Delta Infectivity

This looks a WHOLE LOT like ADE…
39 posted on 09/14/2021 11:40:32 AM PDT by Jan_Sobieski (Sanctification)
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To: rxsid

Can the Vaxxed now sue for being talked into a rushed vaccine that INCREASES their chance of getting delta?


44 posted on 09/14/2021 12:00:55 PM PDT by Bob434
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To: rxsid

This study makes sense.

If we had herd immunized (not shut down or vaccinated) and treated with Z-packs, vitamins and Ivermectin, would we have been better off? Would the virus have run out of gas after 2 months?

I’m thinking, yes.


47 posted on 09/14/2021 12:13:51 PM PDT by mom.mom (...our flag was still there.)
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To: rxsid

I was waiting for some fried chicken yesterday and the guy next to me was rubbing and moving his arm.

He said “I just got my first Vaccine”

I said “I hope you survive”

he started getting all defensive about how it was his choice.

I told him I respected that, and it should be an individual choice.

Then I asked him how much he trusted the govt to be truthful and only do things in his best interest.


48 posted on 09/14/2021 12:28:02 PM PDT by algore ( )
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To: Fred Nerks

Ping to Vax proven ineffective...Japanese study.


49 posted on 09/14/2021 12:37:21 PM PDT by Candor7 ((Obama Fascism:http://www.americanthinker.com/2009/05/barack_obama_the_quintessentia_1.html) )
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To: rxsid

📌


58 posted on 09/14/2021 1:23:41 PM PDT by Varsity Flight ( "War by the prophesies set before you." I Timothy 1:18)
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To: rxsid

yes, but if you read that study through, it’s not just vaccinated. The previously infected reacts the same way, by producing autoantibodies.

However, the authors find the solution to a hypothetical D4 in the last part of the paper :

” When we analyzed the Delta-4+ pseudovirus, some sera from wild-type spike immunized mice showed enhanced infectivity” (that would be ‘naturally acquired”) and “Sera from the Delta-spike immunized mice did not exhibit enhanced infectivity at any concentration of sera. These data suggest that vaccines containing the Delta, but not wild-type, spike might be required to control the Delta subvariant that may emerge in the future.”

Bottom line is, wipe out Delta and other variants before they mutate further:

“These data suggested that the Delta variant completely escaped from anti-NTD neutralizing antibodies while maintaining functional enhancing antibody epitopes. Because the enhancing antibodies decrease the effect of anti-RBD neutralizing antibodies (Li et al., 2021; Liu et al., 2021b), there is a possibility that the Delta variant maintains the infectivity in the presence of anti-RBD neutralizing antibodies as a result of enhancing antibodies.”

“We analyzed these 16 anti-NTD neutralizing antibodies, and found that none of the anti-NTD neutralizing antibodies could recognize Delta spike (Figure 1A). In contrast, when we analyzed the binding of the anti-NTD infectivity-enhancing antibodoies (Li et al., 2021; Liu et al., 2021b), eight out of ten anti-NTD enhancing antibodies bound to Delta spike at levels comparable with wild-type spike “

” Anti-RBD neutralizing antibodies that bound to the Delta spike completely neutralized the infection of either Delta or wild-type pseudovirus (Figure 1C). All anti-NTD neutralizing antibodies we tested failed to recognize the Delta “

“s. Because the enhancing antibodies decrease the effect of anti-RBD neutralizing antibodies (Li et al., 2021; Liu et al., 2021b), there is a possibility that the Delta variant maintains the infectivity in the presence of anti-RBD neutralizing antibodies as a result of enhancing antibodies.”

“All anti-NTD monoclonal neutralizing antibodies from COVID-19 patients failed to bind to Delta spike whereas most of the enhancing antibodies maintained reactivity to Delta spike “


70 posted on 09/15/2021 10:47:50 PM PDT by blueplum ("...this moment is your moment: it belongs to you... " President Donald J. Trump, Jan 20, 2017) )
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