Posted on 09/02/2021 2:01:01 PM PDT by ConservativeMind
Viagra, used to treat sexual impotence, can strongly suppress abnormal heart rhythms known as arrythmias in sheep according to scientists.
In female sheep, the drug—also known as sildenafil—was able to suppress an arrythmia called Torsades de Pointes within 90 seconds by reducing the frequency of irregular heart rhythms caused by abnormal handling of calcium.
It also reduced the probability of Torsades de Pointes, which can lead to sudden cardiac death. However, the team believe the drug could treat other arrythmias as well.
Cardiac arrythmias often follow a heart attack, or result from heart disease. Though often benign , they can cause symptoms including palpitations, breathlessness, fainting and sometimes sudden death.
Treatments such as beta blockers and implantable defibrillators exist, though are not always effective.
Working on isolated sheep heart muscle cells known as myocytes, the research team were also able to measure their calcium stores- as well as their electrical properties.
Although calcium is a key driver of the heart's pumping action, its overload can be a root cause of arrythmias. Viagra was able to suppress the mechanism in the cell which causes calcium overload.
When a small amount calcium enters a myocyte, it triggers the Sarcoplasmic Reticulum (SR)—a calcium store—to release a larger quantity of calcium.
When there is heart disease, the SR can become overloaded with calcium which in turn makes the heart beat at the wrong time- when it is supposed to be resting between beats.
"In 2016, our study of patients with diabetes showed that incidental use of Viagra was linked with reduced heart attack risk and improved heart attack survival."
"In 2019, we found that Viagra can slow or even reverse the progression of heart failure in sheep and this work dramatically extends those important findings providing another tool with which to beat heart disease."
(Excerpt) Read more at medicalxpress.com ...
The wifee has already proclaimed her threat.
According to GoodRX.com, you can get 90 pills at the 100 mg level for $27.81 at the Kroger Pharmacy.
According to GoodRX.com, you can get 90 pills at the highest level (100 mg) for $27.81 at the Kroger Pharmacy.
Back in the 80’s...there was a drug called bretylium. In HUMAN studies...it suppressed or eliminated a very serious cardiac dysrhythmia known as ventricular febrillation. So successful it was called a “chemical defibrillator”...it was approved for human use in usa. Didn’t work. Off usa market for a long time now.
This study is done in isolated sheep heart muscle. This is a very long way from safe human use for the indication.
Only thing I could say is if it is used and the patient dies at least he will have a smile on his face if for a short time...(no pun intended)..
“In 2016, our study of patients with diabetes showed that incidental use of Viagra was linked with reduced heart attack risk and improved heart attack survival.”
Next point?
Lack of Boron in your diet will lead to calcium management problems.
Douglas Labs Ultra Preventative vitamins have Boron included, or you can buy as a separate supplement.
Don't wait until you have problems to begin taking Boron daily.
“It also happens to be effective on neuropathy of the feet, a condition I have”
I have neuropathy of the feet too. I’ve looked at everything to deal with the pain since I can’t get pain medication anymore. Nothing has worked.
Do you take it only as needed or is it a low dose that can be taken daily.
You win the Internet for today!
I read a study once which claimed a ridiculously high cure rate for irregular heartbeats of all kinds from administering the Amino Acid Taurine, the Amino acid Arginine, and Niacin. The article theorized those aminos became essential amino acids in the elderly due to a loss of the ability to synthesize enough of them, and some irregular heartbeats not due to deficiency of them were a deficiency of niacn.
I’m reading that cialix and viagra promote nitric oxide—which declines as we age. Nitric oxide is normally made by the veins and arteries and keeps them supple so blood flows normally through the blood vessels. Nitric oxide goes into steep decline as we age. that makes the blood vessels more brittle and therefor more vulnerable to cracking the inner blood vessel wall called the endothelium— which allows ldl to break past the inner wall and accumulate as plaque. These drugs were developed in the 1990’s as blood pressure medicines. However, their secondary uses made them household names. Now I’m reading that actually nitric oxide plays a much more significant role in the entire endicrine system for both men and women. That the loss of nitric oxide in the body as we age is part of the systemic break down that occurs with the aging process. That just as a matter of retaining good health its a good idea for both men and women to keep nitric oxide at levels we were at many decades before.
You are having a heart attack and the doctor give you viagra.
The doctor says to the nurse to monitor your vitals.
She does and starts to giggle....
Your blood pressure normalizes, you are going be alright.
Your vital is er...
I’m seeing my heart doctor tomorrow for a prescription for the magic blue pill! I really do have an irregular heartbeat!
I dunno, there might be some stiff competition for this thread if a duplicate one starts.
Don’t be too hard on yourself if a second one doesn’t measure up to the length of the first one.
I can hope.
Dobes have these issues, now.
:(
Second's always come up short...
It’s a sloppy deal.
No one likes sloppy seconds ...
IIRC, Viagra was originally developed as a heart medication. Once in use, other “beneficial” side effects were discovered.
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