DETAILS HERE:
https://medicalxpress.com/news/2021-08-covid-biomarker-blood-sphingosine-symptomatic.html
[EXCERPT]
“Just by looking at the data, you can clearly separate the different patient groups, even without doing technical statistical analyses,” said Alhaji Janneh, lead author and graduate student in the Department of Biochemistry and Molecular Biology.
In asymptomatic patients who tested positive for a SARS-CoV-2 antibody, the researchers found a slight increase in serum sphingosine levels—and only sphingosine—compared to patients who tested negative. Remarkably, in patients who developed COVID-19 symptoms, there was a 15-fold reduction in sphingosine levels. Conversely, almost 75% of asymptomatic patients had elevated AC levels while most symptomatic patients had no detectable AC. The presence of serum AC correlates with the increased levels of sphingosine.
“Can this be an alternative way to predict which patients are the most vulnerable to severe disease?” asked Ogretmen, who is also a professor in the Department of Biochemistry and Molecular Biology and the SmartState Endowed Chair in Lipidomics and Drug Discovery. “If we can separate asymptomatic patients from symptomatic patients, we can use limited remedies and resources for patients who are more vulnerable.”
Overall, there is a 99% probability of correctly determining which patients, who have tested positive for SARS-CoV-2 antibodies, will develop disease symptoms versus remain asymptomatic, using blood levels of sphingosine.
These striking results would not have been possible without the MUSC COVID-19 Biorepository and collaboration with the South Carolina Clinical & Translational Research Institute (SCTR). SCTR set up the biorepository to serve as a resource for COVID-19 research, and SCTR co-principal investigator Patrick Flume, M.D. is its director and one of the authors of the article.
Analyzing levels of various lipids from patient samples is expensive and requires sophisticated equipment, making this type of analysis prohibitive under most circumstances. However, the development of an ELISA-based assay—like those used to diagnose HIV infection—to detect levels of AC could provide a cost-effective alternative that could be widely implemented.
Are there nutritional supplements that will increase sphingosine and other sphingolipid levels?
This is really interesting! Thanks.
One of my neighbors has a relative who is a nurse.
She said people with conditions like diabetes and heart problems were thought by the nurses at the local hospital to be highly susceptible.
Could a sphingosine nasal spray prevent COVID-19?
https://www.drugtargetreview.com/news/72711/could-a-sphingosine-nasal-spray-prevent-covid-19/
The team from the University of Cincinnati (UC), US, established that sphingosine – a lipid naturally found in the human body, which is key for cellular lipid metabolism – is important in the local immune defences of epithelial cells, which line the surfaces of the body (eg, skin, blood vessels, urinary tract and organs) and protect them from pathogens.
The biomarker - old, white female that loves multiple cats.
Oops. I thought it was the biomarker for those that feared COVID. Carry on.
In the end the fate of individuals in this COVID pandemic, as in all pandemics, has everything to do with individual genetics and little with masks or lockdowns.
Man or Mouse ?
Nice find.
They are making everyone suffer?
Let’s see if this work gets recognized and extended or ignored as if it never happened.
Drink milk.
In that regard I am a 70+ year old kid, having never lost my appreciation for milk.
https://www.sciencemag.org/news/2014/02/black-death-left-mark-human-genome
The Black Death didn’t just wipe out millions of Europeans during the 14th century. It left a mark on the human genome, favoring those who carried certain immune system genes, according to a new study. Those changes may help explain why Europeans respond differently from other people to some diseases and have different susceptibilities to autoimmune disorders.
Those with the right genetic background survived. The survival genetic information existed. The plague killed those that didn’t have it. There most likely was environmental and nutritional factors. It is selection not mutation of existing gene information. Genetic selection is a much better word than mutation. We learned this basis stuff in science 101 with Mendel.
I call this devolution, we lost genetic information but there is some theory that all the junk DNA still has it and is still available if needed. Tremendous design.
Interesting.
GREAT info! Thanks!
More about Sphingosine :
Sphingosine-1-Phosphate Metabolism in the Regulation of Obesity/Type 2 Diabetes
https://pubmed.ncbi.nlm.nih.gov/32668665/
(Several other articles at link)
Sphingosine as an Inhibitor of Blood Clotting
https://science.sciencemag.org/content/125/3256/1041
Cardiovascular effects of sphingosine-1-phosphate (S1P)
https://pubmed.ncbi.nlm.nih.gov/23563656/
Basically, more fake research from the same people who brought us the fake plandemic to begin with.
They are talking about delta variants and “Safe, effective vaccines’ and identifying COvid -19 with a test that doesn’t identify either the virus or the illness in people.
This fake test will allow them to cherry pick who ‘has’ to get the ‘vaccine’. They’l likely develop a test for this chemical that is itself toxic. I hate to see the merry-go-round continuing to spin, and people hopping on, because it sounds so much like science.
Fauci/NIH/CDC bought scientists and labs/universities with federal funds and they crank out bad data about ‘safe’ and ‘effective’ vaccines but create a new fake chemical ‘test’ to explain why their toxic bioweapons don’t work.
I guess the plandemic continues as long as people listen to it.
“…Their results, published online on July 9 in Scientific Reports, show that reduced levels of a specific lipid, sphingosine, are significantly associated with developing COVID-19 symptoms….”
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I wanted to name our first son Sphingosine Atreides but my wife vetoed the idea.
Just kidding but I’m happy to see research such as this.